公开(公告)号：EP1372706A2

公开(公告)日：2004-01-02

申请号：EP02713807.2

申请日：2002-03-11

申请人： ID Biomedical Corporation of Quebec ,  Jones, David

发明人： BURT, David, S. ,  LOWELL, George, H. ,  WHITE, Gregory, L. ,  JONES, David ,  RIOUX, Clement

IPC分类号： A61K39/02 ,  A61K39/108 ,  A61K39/12 ,  A61K39/095 ,  A61K39/116 ,  A61K39/385 ,  C07H1/00 ,  C07K1/00

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  A61K39/36 ,  A61K39/39 ,  A61K2039/543 ,  A61K2039/55516 ,  A61K2039/55572 ,  A61K2039/70 ,  C12N2760/16134 ,  C12N2760/16151

摘要： An adjuvant complex composed of bacterial outer membrane protein proteosomes complexed to bacterial liposaccharide is prepared to contain the component parts under a variety of conditions. The complex can be formulated with antigenic material to form immunogenic compositions, vaccines and immunotherapeutics. An induced immune response includes protective antibodies and/or type 1 cytokines is shown for a variety of protocols.

公开(公告)号：EP1372706B1

公开(公告)日：2010-12-01

申请号：EP02713807.2

申请日：2002-03-11

申请人： ID Biomedical Corporation of Quebec

发明人： BURT, David, S. ,  LOWELL, George, H. ,  WHITE, Gregory, L. ,  JONES, David ,  RIOUX, Clement

IPC分类号： A61K39/39

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  A61K39/36 ,  A61K39/39 ,  A61K2039/543 ,  A61K2039/55516 ,  A61K2039/55572 ,  A61K2039/70 ,  C12N2760/16134 ,  C12N2760/16151

摘要： An adjuvant complex composed of bacterial outer membrane protein proteosomes complexed to bacterial liposaccharide is prepared to contain the component parts under a variety of conditions. The complex can be formulated with antigenic material to form immunogenic compositions, vaccines and immunotherapeutics. An induced immune response includes protective antibodies and/or type 1 cytokines is shown for a variety of protocols.