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1.发明授权VECTEURS NAVETTES POUR L'INTRODUCTION D'ADN DANS DES MYCOBACTERIES ET UTILISATION DE CES BACTERIES COMME VACCINS 失效将DNA EINSCHAEUSE矢量，分枝杆菌或使用细菌作为疫苗
公开(公告)号：EP0760859B1
公开(公告)日：2003-11-19
申请号：EP95920967.7
申请日：1995-05-19
CPC分类号： C12N9/0004 , C12N9/88 , C12N15/52 , C12N15/74 , C12Y116/01001
摘要： Shuttle vectors for the introduction of DNA into mycobacteria comprising at least one functional replication origin in said mycobacteria, another functional replication origin in other bacteria, an enzymatic cleavage site providing for the insertion of DNA coding for a protein susceptible of being expressed in the mycobacteria, characterized in that the vectors also carry a gene which makes the mycobacteria resistant to a compound containing a heavy metal.
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2.发明公开VECTEURS NAVETTES POUR L'INTRODUCTION D'ADN DANS DES MYCOBACTERIES ET UTILISATION DE CES BACTERIES COMME VACCINS 失效将DNA EINSCHAEUSE矢量，分枝杆菌或使用细菌作为疫苗
公开(公告)号：EP0760859A1
公开(公告)日：1997-03-12
申请号：EP95920967.0
申请日：1995-05-19
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , INSTITUT PASTEUR , INSTITUT PASTEUR DE LILLE
CPC分类号： C12N9/0004 , C12N9/88 , C12N15/52 , C12N15/74 , C12Y116/01001
摘要： Shuttle vectors for the introduction of DNA into mycobacteria comprising at least one functional replication origin in said mycobacteria, another functional replication origin in other bacteria, an enzymatic cleavage site providing for the insertion of DNA coding for a protein susceptible of being expressed in the mycobacteria, characterized in that the vectors also carry a gene which makes the mycobacteria resistant to a compound containing a heavy metal.
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