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公开(公告)号：EP2785848A2
公开(公告)日：2014-10-08
申请号：EP12799032.3
申请日：2012-11-30
IPC分类号： C12P5/02 , C12N9/00 , C07C11/167
CPC分类号： C12P5/026 , C12N9/0004 , C12N9/88 , C12N15/52 , C12Y401/01033 , C12Y402/03027 , Y02E50/343
摘要： This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.
摘要翻译： 该文件描述了通过在丁二烯合成底物中形成两个乙烯基来生产丁二烯的生物化学途径。 本文所述的这些途径依赖酶如甲羟戊酸二磷酸脱羧酶，异戊二烯合酶和脱水酶用于最后的酶促步骤。
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公开(公告)号：EP2861745A2
公开(公告)日：2015-04-22
申请号：EP13739305.4
申请日：2013-06-12
IPC分类号： C12P5/02 , C12N9/00 , C07C11/167 , C12N9/02
CPC分类号： C12N9/0004 , C12P5/026 , C12Y401/01033 , C12Y402/01127 , C12Y402/03027 , Y02E50/343
摘要： This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.
摘要翻译： 该文献描述了通过在丁二烯合成底物中形成两个乙烯基来生产丁二烯的生化途径。 本文描述的这些途径依赖于酶，例如甲羟戊酸二磷酸脱羧酶，异戊二烯合酶和用于最终酶促步骤的脱水酶。
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3.发明公开METHODS OF PRODUCING 7-CARBON CHEMICALS FROM LONG CHAIN FATTY ACIDS VIA OXIDATIVE CLEAVAGE 审中-公开PROCESS FOR通过氧化裂解PRODUCING 7 - 碳CHEMICALS长链脂肪酸
公开(公告)号：EP2938732A1
公开(公告)日：2015-11-04
申请号：EP13824254.0
申请日：2013-12-23
CPC分类号： C12P7/46 , C12P7/18 , C12P7/42 , C12P7/44 , C12P13/001 , C12P13/005
摘要： This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the fatty acid synthesis pathway and oxidative cleavage of long chain acyl-[acp] intermediates by a monooxgenase (e.g., cytochrome P450) such as that encoded by BioI from microorganisms such as Bacillus subtillis.
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