专利检索 ap:("Icahn School of Medicine at Mount Sinai" OR "Universiteit Gent") AND inv:"GARCIA-SASTRE, Adolfo" 第 1 页

1.

发明公开
IMDQ-PEG-CHOL ADJUVANT AND USES THEREOF 审中-公开

公开(公告)号：EP4225366A1

公开(公告)日：2023-08-16

申请号：EP21878555.8

申请日：2021-10-07

申请人： Icahn School of Medicine at Mount Sinai , Universiteit Gent

发明人： GARCIA-SASTRE, Adolfo , SCHOTSAERT, Michael , CHOI, Angela , DE GEEST, Bruno , DE VRIEZE, Jana

IPC分类号： A61K39/39 , A61K47/60 , A61K31/4745 , A61K31/80

2.

发明公开
RECOMBINANT VACCINE AGAINST COVID-19 TO PRODUCE CELLULAR RESPONSE IN INDIVIDUALS WITH PRE-EXISTING IMMUNITY 审中-实审

公开(公告)号：EP4404961A1

公开(公告)日：2024-07-31

申请号：EP22869532.6

申请日：2022-09-20

申请人： Laboratorio Avi-Mex, S.A. De C.V. , Consejo Nacional De Humanidades, Ciencias Y Tecnologías , Icahn School of Medicine at Mount Sinai

发明人： LOZANO DUBERNARD, Bernardo , SOTO PRIANTE, Ernesto , SARFATI MIZRAHI, David , CHAGOYA CORTES, Hector Elias , LOPEZ MACIAS, Constantino III Roberto , PALESE, Peter , GARCIA-SASTRE, Adolfo , KRAMMER, Florian , SUN, Weina , TORRES ROJAS, Martha

IPC分类号： A61K39/215 , A61K31/51 , A61K39/17 , C12N7/01 , C12N15/50 , C12N15/86

CPC分类号： C12N15/86 , C07K14/005 , C12N2770/2002220130101 , C12N2770/2003420130101 , C12N2760/1814320130101 , A61K39/12 , A61K2039/57220130101 , A61K2039/57520130101

3.

发明公开
RECOMBINANT VACCINE AGAINST COVID-19 BASED ON A PARAMYXOVIRUS VIRAL VECTOR 审中-公开

公开(公告)号：EP4151232A1

公开(公告)日：2023-03-22

申请号：EP21804807.2

申请日：2021-02-22

申请人： Laboratorio Avi-Mex, S.A. De C.V. , Icahn School of Medicine at Mount Sinai

发明人： LOZANO-DUBERNARD, Bernardo , SOTO-PRIANTE, Ernesto , SARFATI-MIZRAHI, David , CASTRO-PERALTA, Felipa , PAZ-DE LA ROSA, Georgina , PALESE, Peter , GARCIA-SASTRE, Adolfo , KRAMMER, Florian , SUN, Weina

IPC分类号： A61K39/215 , C12N15/86 , A61P31/14

摘要： An active or inactivated recombinant vaccine against COVID-19 is described that comprises a Newcastle disease viral vector and a pharmaceutically acceptable carrier, adjuvant and/or excipient, characterized in that the viral vector is a virus capable of generating a cellular immune response that has a SARS-CoV-2 exogenous nucleotide sequence inserted.

4.

发明公开
RECOMBINANT NEWCASTLE DISEASE VIRUS EXPRESSING SARS-COV-2 SPIKE PROTEIN AND USES THEREOF 审中-公开

公开(公告)号：EP4146674A2

公开(公告)日：2023-03-15

申请号：EP21800838.1

申请日：2021-05-06

申请人： Icahn School of Medicine at Mount Sinai

发明人： SUN, Weina , KRAMMER, Florian , GARCIA-SASTRE, Adolfo , PALESE, Peter

IPC分类号： C07K14/165 , C07K14/005

5.

发明公开
VEGFR-3-ACTIVATING AGENTS AND ONCOLYTIC VIRUSES AND USES THEREOF FOR THE TREATMENT OF CANCER 审中-公开

公开(公告)号：EP4110803A1

公开(公告)日：2023-01-04

申请号：EP21760173.1

申请日：2021-02-26

申请人： Icahn School of Medicine at Mount Sinai

发明人： SKOBE, Mihaela , EDWARDS, Andrew, Kenneth , FERNANDEZ-RODRIGUEZ, Ruben , GARCIA-SASTRE, Adolfo , MENA, Ignacio , CUADRADO CASTAÑO, Sara

IPC分类号： C07K14/71 , A61P35/00 , A61K35/768

6.

发明授权
VACCINES FOR USE IN THE PROPHYLAXIS AND TREATMENT OF INFLUENZA VIRUS DISEASE 有权

公开(公告)号：EP2536425B1

公开(公告)日：2019-06-19

申请号：EP11745345.6

申请日：2011-02-18

申请人： Icahn School of Medicine at Mount Sinai

发明人： GARCIA-SASTRE, Adolfo , PALESE, Peter , WANG, Taia, T. , TAN, Gene, S.

IPC分类号： A61K38/16 , A61K38/00 , A61K39/12 , C07K14/005 , C07K14/11 , A61K39/00

7.

发明公开
INFLUENZA VIRUS HEMAGGLUTININ PROTEINS AND USES THEREOF 审中-公开

公开(公告)号：EP3471767A1

公开(公告)日：2019-04-24

申请号：EP17813990.3

申请日：2017-06-14

申请人： Icahn School of Medicine at Mount Sinai

发明人： PALESE, Peter , GARCIA-SASTRE, Adolfo , KRAMMER, Florian , ERMLER, Megan

IPC分类号： A61K39/12 , A61K39/145 , C07K14/005 , C12N7/00

8.

发明授权
CHIMERIC NEWCASTLE DISEASE VIRUSES AND USES THEREOF 有权

公开(公告)号：EP2987856B1

公开(公告)日：2018-07-25

申请号：EP15162322.0

申请日：2010-02-05

申请人： Icahn School of Medicine at Mount Sinai , Memorial Sloan Kettering Cancer Center

发明人： ZAMARIN, Dmitriy , GARCIA-SASTRE, Adolfo , PALESE, Peter , FONG, Yuman

IPC分类号： C12N7/00 , A61K35/76 , C07K14/125 , C07K14/11

CPC分类号： C12N7/00 , A61K35/13 , A61K39/0011 , A61K39/17 , C07K14/005 , C12N2760/16122 , C12N2760/18121 , C12N2760/18122 , C12N2760/18132 , C12N2760/18143 , C12N2760/18171

摘要： The invention provides chimeric Newcastle disease viruses (NDV) engineered to express a heterologous interferon antagonist, a modified F protein, and a cytokine. Further provided are pharmaceutical compositions comprising such chimeric viruses, methods for producing said pharmaceutical compositions and their use in a method for treating cancer in a subject. Provided are also cells and non-human embryonated eggs comprising the chimeric NDV viruses of the invention.

9.

发明公开
METHODS AND COMPOSITIONS FOR BAT IPSC PREPARATION AND USE 审中-实审

公开(公告)号：EP4408977A2

公开(公告)日：2024-08-07

申请号：EP22873913.2

申请日：2022-09-26

申请人： Icahn School of Medicine at Mount Sinai

发明人： ZWAKA, Thomas P. , DEJOSEZ ZWAKA, Marion , GARCIA-SASTRE, Adolfo

IPC分类号： C12N5/0735 , C12N5/02 , C12N15/85

CPC分类号： C12N5/0696 , C12N2501/60220130101 , C12N2501/60320130101 , C12N2501/60420130101 , C12N2501/60620130101 , C12N2506/130720130101 , C12N2501/11520130101 , C12N2501/12520130101 , C12N2501/23520130101 , C12N2533/5420130101 , C12N2502/132320130101 , C12N2513/0020130101 , C12N2501/4220130101 , C12N2501/4120130101 , C12N7/00 , C12N2770/2002120130101 , C12N2770/2005120130101 , C12N2740/1302120130101 , C12N2770/2003420130101 , C12N2770/3612120130101

10.

发明公开
USE OF MULTI-KINASE INHIBITORS TO TREAT RNA VIRUS INFECTIONS 审中-公开

公开(公告)号：EP4161922A1

公开(公告)日：2023-04-12

申请号：EP21822105.9

申请日：2021-06-08

申请人： Icahn School of Medicine at Mount Sinai

发明人： REDDY, Premkumar , GARCIA-SASTRE, Adolfo , REDDY, M., V. Ramana , WHITE, Kris

IPC分类号： C07D417/06 , C07D279/14 , C07D279/10 , C07D279/16 , A61P31/14 , A61P31/16