公开(公告)号：EP1456655A2

公开(公告)日：2004-09-15

申请号：EP02804422.0

申请日：2002-11-13

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  YANG, Junming ,  GIETZEN, Kimberly, J. ,  LEE, Soo, Yeun ,  TANG, Y. , Tom ,  AZIMZAI, Yalda ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  BARROSO, Ines ,  BECHA, Shanya, D. ,  YUE, Henry ,  LEHR-MASON, Patricia, M. ,  THANGAVELU, Kavitha ,  LEE, Sally ,  EMERLING, Brooke, M. ,  KABLE, Amy, E. ,  KHARE, Reena ,  BAUGHN, Mariah, R. ,  GANDHI, Ameena, R. ,  TRAN, Uyen, K. ,  RICHARDSON, Thomas, W. ,  MARQUIS, Joseph, P. ,  LAL, Preeti, G. ,  FORSYTHE, Ian,J. ,  LEE, Ernestine, A. ,  SWARNAKAR, Anita ,  KALLICK, Deborah, A. ,  GRIFFIN, Jennifer, A. ,  ELLIOTT, Vicki, S. ,  GORVAD, Ann, E. ,  HALFALIA, April, J.A. ,  ISON, Craig, H. ,  JIN, Pei ,  JIANG, Xin ,  JACKSON, Alan, A. ,  BHATIA, Umesh ,  BURRILL, John, D. ,  BLAKE, Julie, J. ,  HO, Anne ,  ZHENG, Wenijn ,  GAO, Jing

IPC分类号： G01N33/53 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/705 ,  C07K14/47

摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与REMAP异常表达相关的病症的方法。

公开(公告)号：EP1434860A2

公开(公告)日：2004-07-07

申请号：EP02783990.1

申请日：2002-09-26

申请人： Incyte Genomics, Inc.

发明人： YANG, Junming ,  LU, Dyung Aina, M. ,  YUE, Henry ,  ELLIOTT, Vicki, S. ,  WARREN, Bridget, A. ,  DUGGAN, Brendan, M. ,  FORSYTHE, Ian, J. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  GORVAD, Anne, E. ,  TRAN, Uyen, K. ,  LI, Joana, X. ,  YAO, Monique, G. ,  ISON, Craig, H. ,  GRIFFIN, Jennifer, A. ,  CHANG, Hsin-Ru ,  EMERLING, Brooke, M. ,  TANG, Y. Tom ,  LAL, Preeti G. ,  KABLE, Amy E. ,  MARQUIS, Joseph P. ,  JIANG, Xin ,  JACKSON, Alan A. ,  ZEBARJADIAN, Yeganeh ,  SWARNAKAR, Anita ,  WILSON, Amy D. ,  JIN, Pei ,  RICHARDSON, Thomas W. ,  BHATIA, Umesh ,  BURRILL, John C. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin ,  GAO, Jing ,  LEE, Soo Yeun

IPC分类号： C12N9/00 ,  C12N9/14 ,  C12N9/16 ,  C07K16/00 ,  C07K1/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/20

摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.