公开(公告)号：EP1485474A2

公开(公告)日：2004-12-15

申请号：EP02795774.5

申请日：2002-12-06

申请人： Incyte Genomics, Inc.

发明人： KABLE, Amy, E. ,  CHIEN, David ,  WILSON, Amy, D. ,  SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J., A. ,  EMERLING, Brooke, M. ,  RAMKUMAR, Jayalaxmi ,  JIN, Pei ,  GRIFFIN, Jennifer, A. ,  MARQUIS, Joseph, P. ,  BAUGHN, Mariah, R. ,  CHAWLA, Narinder, K. ,  LEHR-MASON, Patricia, M. ,  KHARE, Reena ,  LEE, Sally ,  HAWKINS, Phillip, R. ,  BECHA, Shanya, D. ,  LEE, Soo, Yeun ,  ZEBARJADIAN, Yeganeh

IPC分类号： C12N9/16 ,  A61K38/00 ,  A61K38/46

CPC分类号： C12N9/1205 ,  C12N9/16

摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

公开(公告)号：EP1466005A1

公开(公告)日：2004-10-13

申请号：EP02792417.4

申请日：2002-12-17

申请人： Incyte Genomics, Inc.

发明人： MARQUIS, Joseph, P. ,  LAL, Preeti, G. ,  GRIFFIN, Jennifer, A. ,  ELLIOTT, Vicki, S. ,  KHARE, Reena ,  BAUGHN, Mariah, R. ,  HAFALIA, April, J.A. ,  BECHA, Shanya, D. ,  LEHR-MASON, Patricia, M. ,  LEE, Soo, Yeun

IPC分类号： C12P21/06 ,  C12N1/20 ,  C12N9/00 ,  C12N9/24 ,  C12N15/00

CPC分类号： C12N9/00 ,  C07K14/4726

摘要： Various embodiments of the invention provide human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.

公开(公告)号：EP1434788A2

公开(公告)日：2004-07-07

申请号：EP02766420.0

申请日：2002-09-26

申请人： Incyte Genomics, Inc.

发明人： AZIMZAI, Yalda ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  GANDHI, Ameena, R. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  ISON, Craig, H. ,  KABLE, Amy, E. ,  KALAFUS, Daniel, P. ,  LEHR-MASON, Patricia, M. ,  LU, Dyung Aina, M. ,  MARQUIS, Joseph, P. ,  NGUYEN, Danniel, B. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas W. ,  KAREHT, Stephanie K. ,  SWARNAKAR, Anita ,  TANG, Y. Tom ,  TRAN, Uyen K. ,  WARREN, Bridget A. ,  XU, Yuming ,  YAO, Monique G. ,  YUE, Huibin ,  YUE, Henry

IPC分类号： C07K1/00 ,  A61K39/00 ,  C12Q1/00 ,  G01N33/53

CPC分类号： A01K67/00 ,  A61K38/00 ,  A61K38/17 ,  A61K39/00 ,  A61K39/395 ,  A61K45/00 ,  C07K1/00 ,  C07K14/47 ,  C07K14/475 ,  C07K16/18 ,  C12M1/00 ,  C12N1/00 ,  C12N5/10 ,  C12N15/02 ,  C12N15/09 ,  C12P21/02 ,  C12Q1/00 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50 ,  G01N33/53 ,  G01N37/00

摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides whichidentify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.

公开(公告)号：EP1578902A2

公开(公告)日：2005-09-28

申请号：EP02761662.2

申请日：2002-09-12

申请人： Incyte Genomics, Inc.

发明人： HONCHELL, Cynthia, D. ,  WARREN, Bridget, A. ,  BOROWSKY, Mark, L. ,  GRIFFIN, Jennifer, A. ,  LI, Joana, X. ,  LEE, Soo, Yeun ,  YUE, Henry ,  FORSYTHE, Ian, J. ,  MARQUIS, Joseph, P. ,  GIETZEN, Kimberly, J. ,  BAUGHN, Mariah, R. ,  TRAN, Uyen, K. ,  LEHR-MASON, Patricia, M. ,  TANG, Y., Tom ,  RAMKUMAR, Jayalaxmi ,  EMERLING, Brooke, M. ,  LEE, Ernestine, A. ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J.A. ,  DUGGAN, Brendan M. ,  CHAWLA, Narinder K. ,  KABLE, Amy E. ,  CHANG, Hsin-Ru ,  KHARE, Reena ,  BECHA, Shanya D. ,  JIN, Pei ,  LEE, Sally

IPC分类号： C12N1/00

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/47 ,  C07K14/475 ,  C07K14/78 ,  C07K2319/00

摘要： Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1456655A2

公开(公告)日：2004-09-15

申请号：EP02804422.0

申请日：2002-11-13

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  YANG, Junming ,  GIETZEN, Kimberly, J. ,  LEE, Soo, Yeun ,  TANG, Y. , Tom ,  AZIMZAI, Yalda ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  BARROSO, Ines ,  BECHA, Shanya, D. ,  YUE, Henry ,  LEHR-MASON, Patricia, M. ,  THANGAVELU, Kavitha ,  LEE, Sally ,  EMERLING, Brooke, M. ,  KABLE, Amy, E. ,  KHARE, Reena ,  BAUGHN, Mariah, R. ,  GANDHI, Ameena, R. ,  TRAN, Uyen, K. ,  RICHARDSON, Thomas, W. ,  MARQUIS, Joseph, P. ,  LAL, Preeti, G. ,  FORSYTHE, Ian,J. ,  LEE, Ernestine, A. ,  SWARNAKAR, Anita ,  KALLICK, Deborah, A. ,  GRIFFIN, Jennifer, A. ,  ELLIOTT, Vicki, S. ,  GORVAD, Ann, E. ,  HALFALIA, April, J.A. ,  ISON, Craig, H. ,  JIN, Pei ,  JIANG, Xin ,  JACKSON, Alan, A. ,  BHATIA, Umesh ,  BURRILL, John, D. ,  BLAKE, Julie, J. ,  HO, Anne ,  ZHENG, Wenijn ,  GAO, Jing

IPC分类号： G01N33/53 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/705 ,  C07K14/47

摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与REMAP异常表达相关的病症的方法。

公开(公告)号：EP1434796A2

公开(公告)日：2004-07-07

申请号：EP02776174.1

申请日：2002-10-03

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  TRAN, Uyen, K. ,  DUGGAN, Brendan, M. ,  THANGAVELU, Kavitha ,  YANG, Junming ,  XU, Yuming ,  TANG, Tom, Y. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  FORSYTHE, Ian, J. ,  BECHA, Shanya, D. ,  YAO, Monique, G. ,  EMERLING, Brooke, M. ,  GRIFFIN, Jennifer, A. ,  LAL, Preeti, G. ,  ZEBARJADIAN, Yeganeh ,  BAUGHN, Mariah, R. ,  LEE, Ernestine A. ,  LEE, Soo Yeun ,  RAMKUMAR, Jayalaxmi ,  GORVAD, Ann E. ,  KABLE, Amy E. ,  LU, Dyung Aina M. ,  BOROWSKY, Mark L.

IPC分类号： C07K14/475 ,  A61K38/18

CPC分类号： C07K14/47 ,  A01K2217/05 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。

公开(公告)号：EP1423415A2

公开(公告)日：2004-06-02

申请号：EP02793765.5

申请日：2002-08-16

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  GRIFFIN, Jennifer, A. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  YAO, Monique, G. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas, W. ,  BECHA, Shanya, D. ,  LEE, Ernestine, A. ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  BAUGHN, Mariah, R. ,  LI, Joana, X. ,  DUGGAN, Brendan, M. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  BOROWSKY, Mark L. ,  ISON, Craig H. ,  THANGAVELU, Kavitha ,  XU, Yuming ,  LEE, Sally ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  AZIMZAI, Yalda ,  HAFALIA, April J.A. ,  DING, Li ,  NGUYEN, Danniel B. ,  HONCHELL, Cynthia D. ,  LUO, Wen ,  CHWALA, Narinder K. ,  MARQUIS, Joseph P. ,  JACKSON, Jennifer L. ,  TRAN, Uyen K.

IPC分类号： C07K14/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C07K14/47 ,  G01N2500/04

摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与INTSIG的异常表达相关的病症的方法。

公开(公告)号：EP1521822A2

公开(公告)日：2005-04-13

申请号：EP02773383.1

申请日：2002-09-13

申请人： Incyte Genomics, Inc.

发明人： SPRAGUE, William, W. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  TANG, Y., Tom ,  ELLIOTT, Vicki, S. ,  MARQUIS, Joseph, P. ,  LI, Joana, X. ,  GRIFFIN, Jennifer, A. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  LU, Dyung Aina, M. ,  EMERLING, Brooke, M. ,  DUGGAN, Brendan, M. ,  RICHARDSON, Thomas, W. ,  LEE, Soo, Yeun ,  RAMKUMAR, Jayalaxmi ,  BECHA, Shanya, D. ,  LEHR-MASON, Patricia, M. ,  SWARNAKAR, Anita ,  TRAN, Uyen K. ,  KABLE, Amy E. ,  HAFALIA, April J.A. ,  KHARE, Reena

IPC分类号： C12N9/00 ,  C07H21/04

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12N9/6421

摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.

公开(公告)号：EP1434785A2

公开(公告)日：2004-07-07

申请号：EP02780461.6

申请日：2002-10-11

申请人： Incyte Genomics, Inc.

发明人： RAMKUMAR, Jayalaxmi ,  GORVAD, Ann, E. ,  BAUGHN, Mariah, R. ,  EMERLING, Brooke, M. ,  YANG, Junming ,  LEE,soo,Yeun ,  TRAN, Uyen, K. ,  BECHA, Shanya, D. ,  DUGGAN, Brendan, M. ,  LEE, Ernestine, A. ,  GRIFFIN, Jennifer, A. ,  LI,Joana, X. ,  SPRAGUE, William, W. ,  HAFALIA, April, J.A. ,  CHAWLA, Narinder, K. ,  LEHR-MASON, Patricia, M. ,  KABLE, Amy, E. ,  YUE, Henry ,  MARQUIS, Joseph, P. ,  YAO, Monique G. ,  RICHARDSON, Thomas W. ,  TANG, Tom Y. ,  JIN, Pei ,  CHIEN, David ,  BHATIA, Umesh ,  BURRILL, John D. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C07H21/04 ,  C12N1/20 ,  C12N9/00

CPC分类号： A01K67/00 ,  A61K38/00 ,  A61K38/17 ,  A61K39/395 ,  A61K45/00 ,  C07H21/04 ,  C07K14/47 ,  C07K16/18 ,  C07K16/40 ,  C12M1/00 ,  C12N1/20 ,  C12N5/10 ,  C12N9/00 ,  C12N15/02 ,  C12N15/09 ,  C12N15/52 ,  C12P21/02 ,  C12Q1/68 ,  G01N1/00 ,  G01N33/15 ,  G01N33/50 ,  G01N33/53 ,  G01N33/566

摘要： Various embodiments of the invention provide human protein modification and maintenance molecules(PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.

公开(公告)号：EP1417224A2

公开(公告)日：2004-05-12

申请号：EP02763529.1

申请日：2002-08-15

申请人： Incyte Genomics, Inc.

发明人： TANG, Tom, Y. ,  WARREN, Bridget, A. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  YUE, Henry ,  HONCHELL, Cynthia, D. ,  LEHR-MASON, Patricia, M. ,  BURFORD, Neil ,  XU, Yuming ,  BAUGHN, Mariah, R. ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  LEE, Ernestine, A. ,  FORSYTHE, Ian, J. ,  RICHARDSON, Thomas, W. ,  LEE, Sally ,  THANGAVELU, Kavitha ,  YUE, Huibin ,  EMERLING, Brooke, M. ,  CHAWLA, Narinder K. ,  AZIMZAI, Yalda ,  SANJANWALA, Bharati ,  HAFALIA, April J.A. ,  BOROWSKY, Mark L. ,  NGUYEN, Danniel B. ,  ISON, Craig H. ,  ASTROMOFF, Anna ,  DING, Li ,  LEE, Soo Yeun ,  BECHA, Shanya D. ,  RAMKUMAR, Jayalaxmi ,  GANDHI, Ameena r. ,  JIN, Pei ,  FU, Glenn K. ,  SWARNAKAR, Anita

IPC分类号： C07K14/00 ,  C12P21/06 ,  A61K38/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/705 ,  C12N9/1205 ,  C12N9/16 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。