公开(公告)号：EP1451212A2

公开(公告)日：2004-09-01

申请号：EP02780462.4

申请日：2002-10-10

申请人： Incyte Genomics, Inc.

发明人： BECHA, Shanya, D. ,  BHATIA, Umesh ,  BLAKE, Julie, J. ,  BOROWSKY, Mark, L. ,  BURRILL, John, D. ,  CHANG, Hsin-Ru ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J., A. ,  HO, Anne ,  ISON, Craig, H. ,  KABLE, Amy, E. ,  KHARE, Reena ,  LAL, Preeti, G. ,  LEE, Sally ,  LEE, Ernestine A. ,  LEE, Soo Yeun ,  LEHR-MASON, Patricia M. ,  LI, Joana X. ,  LINDQUIST, Erika A. ,  LUO, Wen ,  MARQUIS, Joseph P. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas W. ,  SPRAGUE, William W. ,  SWARNAKAR, Anita ,  TANG, Y. Tom ,  WARREN, Bridget A. ,  YANG, Junming ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh ,  ZHENG, Wenjin

IPC分类号： C07K14/00 ,  C12P21/06 ,  A61K38/00

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Various embodiments of the invention provide human structural and cytoskeleton-associated proteins (SCAP) and polynucleotides which identify and encode SCAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SCAP.

公开(公告)号：EP1430130A2

公开(公告)日：2004-06-23

申请号：EP02726569.3

申请日：2002-02-07

申请人： Incyte Genomics, Inc.

发明人： THORNTON, Michael, B. ,  HAFALIA, April, J., A. ,  LU, Dyung, Aina, M. ,  ARVIZU, Chandra, S. ,  SWARNAKAR, Anita ,  LU, Yan ,  WARREN, Bridget, A. ,  BAUGHN, Mariah, R. ,  TANG, Y., Tom ,  LEE, Ernestine, A. ,  YAO, Monique, G. ,  RAMKUMAR, Jayalaxmi ,  KHAN, Farrah, A. ,  GANDHI, Ameena, R. ,  DING, Li ,  YUE, Henry ,  GIETZEN, Kimberly, J. ,  CHAWLA, Narinder, K. ,  THANGAVELU, Kavitha ,  ELLIOT, Vicki S. ,  MARQUIS, Joseph P.

IPC分类号： C12N15/12

CPC分类号： C07K14/4702 ,  C07K14/47

摘要： The invention provides human nucleic acis-associated protein (NAAP) and polynucleotides which identify and encode NAAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

公开(公告)号：EP1478745A2

公开(公告)日：2004-11-24

申请号：EP02731940.9

申请日：2002-05-23

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  AZIMZAI, Yalda ,  DING, Li ,  LEE, Ernestine, A. ,  HAFALIA, April, J., A. ,  BECHA, Shanya, D. ,  TANG, Y., Tom ,  LAL, Preeti, G. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  RAMKUMAR, Jayalaxmi ,  ELLIOTT, Vicki, S. ,  ARVIZU, Chandra, S. ,  LUO, Wen ,  SWARNAKAR, Anita ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  GANDHI, Ameena R. ,  YAO, Monique G. ,  KHAN, Farrah A. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas W. ,  MARQUIS, Joseph P. ,  CHIEN, David ,  JIN, Pei

IPC分类号： C12N9/20 ,  C12N9/14 ,  C12N15/00 ,  C12N5/00 ,  C12N1/20 ,  C07K1/00 ,  C07H21/04 ,  C07H21/02 ,  C12Q1/68

CPC分类号： C12N9/1205 ,  C12N9/16

摘要： The invention provides human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明提供了识别和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1368472A2

公开(公告)日：2003-12-10

申请号：EP02704382.7

申请日：2002-02-08

申请人： Incyte Genomics, Inc.

发明人： LAL, Preeti, G. ,  BAUGHN, Mariah, R. ,  YAO, Monique, G. ,  CHAWLA, Narinder, K. ,  ELLIOT, Vicki, S. ,  XU, Yuming ,  HONCHELL, Cynthia, D. ,  YUE, Henry ,  DING, Li ,  GIETZEN, Kimberly, J. ,  ISON, Craig, H. ,  LU, Dyung, Aina, M. ,  HAFALIA, April, J., A. ,  GANDHI, Ameena, R. ,  THANGAVELU, Kavitha ,  SANJANWALA, Madhusudan, M. ,  TANG, Y., Tom ,  RAMKUMAR, Jayalaxmi ,  GRIFFIN, Jennifer, A. ,  SWARNAKAR, Anita ,  AZIMZAI, Yalda ,  KAREHT, Stephanie K. ,  BURFORD, Neil ,  LEE, Ernestine A. ,  LU, Yan ,  TRAN, Uyen K. ,  MARQUIS, Joseph P.

IPC分类号： C12N15/12 ,  C12N5/10 ,  C12Q1/68 ,  C07K14/47 ,  C07K16/18 ,  G01N33/50 ,  G01N33/68 ,  A01K67/027 ,  A61K38/17 ,  A61K39/395

CPC分类号： C12N9/6421 ,  A61K38/00 ,  C07K14/47

摘要： The invention provides full-length human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1480994A1

公开(公告)日：2004-12-01

申请号：EP02792392.9

申请日：2002-12-12

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  BHATIA, Umesh ,  BLAKE, Julie, J. ,  BURRILL, John, D. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  HO, Anne ,  JACKSON, Alan, A. ,  JIANG, Xin ,  KABLE, Amy, E. ,  KEARNEY, Liam ,  KHARE, Reena ,  LEE, Ernestine, A. ,  LEE, Sally ,  LU, Dyung Aina M. ,  MARQUIS, Joseph P. ,  LEHR-MASON, Patricia M. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas W. ,  SPRAGUE, William W. ,  TRAN, Uyen K. ,  CHAWLA, Narinder K. ,  WARREN, Bridget A. ,  YUE, Henry ,  ZHENG, Wenjin

IPC分类号： C07H21/04 ,  C12N15/00 ,  C12N15/85 ,  C12N15/86 ,  C07K5/00 ,  C07K14/00 ,  A61K38/00

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1434860A2

公开(公告)日：2004-07-07

申请号：EP02783990.1

申请日：2002-09-26

申请人： Incyte Genomics, Inc.

发明人： YANG, Junming ,  LU, Dyung Aina, M. ,  YUE, Henry ,  ELLIOTT, Vicki, S. ,  WARREN, Bridget, A. ,  DUGGAN, Brendan, M. ,  FORSYTHE, Ian, J. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  GORVAD, Anne, E. ,  TRAN, Uyen, K. ,  LI, Joana, X. ,  YAO, Monique, G. ,  ISON, Craig, H. ,  GRIFFIN, Jennifer, A. ,  CHANG, Hsin-Ru ,  EMERLING, Brooke, M. ,  TANG, Y. Tom ,  LAL, Preeti G. ,  KABLE, Amy E. ,  MARQUIS, Joseph P. ,  JIANG, Xin ,  JACKSON, Alan A. ,  ZEBARJADIAN, Yeganeh ,  SWARNAKAR, Anita ,  WILSON, Amy D. ,  JIN, Pei ,  RICHARDSON, Thomas W. ,  BHATIA, Umesh ,  BURRILL, John C. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin ,  GAO, Jing ,  LEE, Soo Yeun

IPC分类号： C12N9/00 ,  C12N9/14 ,  C12N9/16 ,  C07K16/00 ,  C07K1/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/20

摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

公开(公告)号：EP1423415A2

公开(公告)日：2004-06-02

申请号：EP02793765.5

申请日：2002-08-16

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  GRIFFIN, Jennifer, A. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  YAO, Monique, G. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas, W. ,  BECHA, Shanya, D. ,  LEE, Ernestine, A. ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  BAUGHN, Mariah, R. ,  LI, Joana, X. ,  DUGGAN, Brendan, M. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  BOROWSKY, Mark L. ,  ISON, Craig H. ,  THANGAVELU, Kavitha ,  XU, Yuming ,  LEE, Sally ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  AZIMZAI, Yalda ,  HAFALIA, April J.A. ,  DING, Li ,  NGUYEN, Danniel B. ,  HONCHELL, Cynthia D. ,  LUO, Wen ,  CHWALA, Narinder K. ,  MARQUIS, Joseph P. ,  JACKSON, Jennifer L. ,  TRAN, Uyen K.

IPC分类号： C07K14/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C07K14/47 ,  G01N2500/04

摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与INTSIG的异常表达相关的病症的方法。

公开(公告)号：EP1387888A2

公开(公告)日：2004-02-11

申请号：EP01992356.4

申请日：2001-12-19

申请人： Incyte Genomics, Inc.

发明人： BAUGHIN, Mariah, R. ,  LU, Yan ,  ARVIZU, Chandra S. ,  RAMKUMAR, Jayalaxmi ,  YAO, Monique, G. ,  POLICKY, Jennifer, L. ,  CHAWLA, Narinder, K. ,  TRIBOULEY, Katherine, M. ,  YUE, Henry ,  BATRA, Sjeev ,  DING, Li ,  LAL, Preeti, G. ,  BOROWSKY, Mark, L. ,  LU, Dyung, Aina, M. ,  GANDHI, Ameena, R. ,  GRIFFIN, Jennifer, A. ,  XU, Yuming ,  AZIMZAI, Yalda ,  GIETZEN, Kimberly, J. ,  TANG, Y. Tom ,  WARREN, Bridget A. ,  MASON, Patricia M. ,  BURFORD, Neil ,  HAFALIA, April J.A. ,  LEE, Ernestine A. ,  YANG, Junming ,  GORVAD, Ann E. ,  EMERLING, Brooke M. ,  MARQUIS, Joseph P. ,  LEE, Soo Yeun ,  SWARNAKAR, Anita ,  REDDY, Roopa ,  JIANG, Xin ,  JACKSON, Alan, A.

IPC分类号： C12N15/12 ,  C07K14/47 ,  A01K67/027 ,  C12N5/10 ,  C07K16/18 ,  C12Q1/68 ,  G01N33/68

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  G01N33/6875 ,  G01N2500/00 ,  Y02A50/55 ,  Y02A50/58

摘要： The invention provides human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. The invention also provides expression vectors. host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.