公开(公告)号：EP2516567B1

公开(公告)日：2016-08-03

申请号：EP10842733.7

申请日：2010-12-21

申请人： Innovative Surface Technologies, Inc.

发明人： WEN, Jie ,  TATON, Kristin ,  LAWIN, Laurie ,  KNOPKE, William ,  GUIRE, Eric ,  GUIRE, Patrick

IPC分类号： C09D173/02 ,  C09D133/02 ,  C09D139/06 ,  C08J7/06 ,  C09D135/08 ,  C09D201/02 ,  C09D131/00

CPC分类号： C08F8/42 ,  A61L29/06 ,  A61L29/085 ,  A61L29/14 ,  A61L29/16 ,  A61L31/022 ,  A61L31/06 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/0005 ,  A61L2300/404 ,  A61L2300/42 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  B05D3/06 ,  C08F8/28 ,  C08F8/30 ,  C08F267/04 ,  C09D131/00 ,  C09D135/00 ,  Y10T428/31507 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31598 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31721 ,  Y10T428/3175 ,  Y10T428/31797 ,  Y10T428/31855 ,  Y10T428/31884 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31928 ,  C08F222/06

公开(公告)号：EP2988730A1

公开(公告)日：2016-03-02

申请号：EP14788719.4

申请日：2014-04-25

申请人： Innovative Surface Technologies, Inc.

发明人： TATON, Kristin ,  LAWIN, Laurie ,  GUIRE, Patrick

IPC分类号： A61K9/00

CPC分类号： A61L29/085 ,  A61L27/34 ,  A61L27/54 ,  A61L29/06 ,  A61L29/106 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/602 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  C08L83/04

摘要： The present disclosure relates to multilayer coatings that include a hydrophobic encasing layer and allow controlled release of a water soluble drug. The encasing layer encases water soluble, or hydrophilic, drugs with a flexible layer and comes in good intimate contact with the water soluble drug layer. Thus, the encasing layer conforms to the water soluble drug and can control the release of the drug. Advantageously, major cuts or fissures in the coating do not cause the water soluble drug to leak or burst out; rather, the encasing layer continues to provide modulated release of the drug. The present disclosure also includes methods of making the multilayer coatings, methods of using the multilayer coatings, and articles that include the multilayer coatings.

公开(公告)号：EP2516567A1

公开(公告)日：2012-10-31

申请号：EP10842733.7

申请日：2010-12-21

申请人： Innovative Surface Technologies, Inc.

发明人： WEN, Jie ,  TATON, Kristin ,  LAWIN, Laurie ,  KNOPKE, William ,  GUIRE, Eric ,  GUIRE, Patrick

IPC分类号： C09D173/02 ,  C09D133/02 ,  C09D139/06 ,  C08J7/06 ,  C09D135/08

CPC分类号： C08F8/42 ,  A61L29/06 ,  A61L29/085 ,  A61L29/14 ,  A61L29/16 ,  A61L31/022 ,  A61L31/06 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/0005 ,  A61L2300/404 ,  A61L2300/42 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  B05D3/06 ,  C08F8/28 ,  C08F8/30 ,  C08F267/04 ,  C09D131/00 ,  C09D135/00 ,  Y10T428/31507 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31598 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31721 ,  Y10T428/3175 ,  Y10T428/31797 ,  Y10T428/31855 ,  Y10T428/31884 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31928 ,  C08F222/06

摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.

摘要翻译： 本发明描述了包含聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团的新型涂布剂，所述非共价连接基团选择为与涂布所述涂布剂的基材相互作用。 涂层剂可用于提供可进一步官能化（例如，通过施加附加涂层）或为表面提供所需性能的涂层。