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公开(公告)号：EP2516567A1
公开(公告)日：2012-10-31
申请号：EP10842733.7
申请日：2010-12-21
发明人： WEN, Jie , TATON, Kristin , LAWIN, Laurie , KNOPKE, William , GUIRE, Eric , GUIRE, Patrick
IPC分类号： C09D173/02 , C09D133/02 , C09D139/06 , C08J7/06 , C09D135/08
CPC分类号： C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.
摘要翻译： 本发明描述了包含聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团的新型涂布剂，所述非共价连接基团选择为与涂布所述涂布剂的基材相互作用。 涂层剂可用于提供可进一步官能化（例如，通过施加附加涂层）或为表面提供所需性能的涂层。
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2.发明公开BRUSH POLYMER COATING BY IN SITU POLYMERIZATION FROM PHOTOREACTIVE SURFACE 审中-公开刷聚合物涂层原位聚合法制备一个光反应的表面
公开(公告)号：EP2403836A2
公开(公告)日：2012-01-11
申请号：EP10749167.2
申请日：2010-03-02
发明人： WEN, Jie , LAWIN, Laurie, R. , GUIRE, Patrick
IPC分类号： C07D239/10 , C09D201/00 , C08G61/12
CPC分类号： A61L29/085 , A61F2/30767 , A61F2/3094 , A61F2002/30673 , A61L27/00 , A61L27/34 , A61L27/50 , A61L31/10 , A61L2430/24 , C09D4/00 , Y10T428/31855 , Y10T428/31935
摘要： The invention provides compositions that include crosslinking agents having multiple photoactivatable groups, such as diaryl ketones, or a diaryl ketone, such as benzophenone, and at least one polymerizable monomer, such as a zwitterionic monomer. The compositions are useful as surface coating agents that provide brush type polymeric coatings. These polymeric coatings can be used on medical devices, such as artificial joints, to reduce wear and tear between the components of the joint and thus reduce or eliminate debris generated by friction between the joint components.
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公开(公告)号：EP2344212A1
公开(公告)日：2011-07-20
申请号：EP09815046.9
申请日：2009-09-15
CPC分类号： A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/404 , A61L2300/624 , A61L2400/12 , A61L2420/04
摘要： The invention describes nanotextured super hydrophobic coatings that contain active agents which can elute from the coating over a period of time.
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公开(公告)号：EP2118189A1
公开(公告)日：2009-11-18
申请号：EP08743567.3
申请日：2008-02-27
发明人： LAWIN, Laurie, R. , GUIRE, Patrick , WEN, Jie , TATON, Kristin
IPC分类号： C08K3/00 , C08K3/36 , C08K5/00 , C08K7/00 , C08K7/24 , C08K7/26 , C08K9/00 , C08K9/06 , C09D201/00
CPC分类号： C09D125/10 , C08K3/08 , C08K3/22 , C08K5/1525 , C08K9/06 , C09D5/00 , C09D7/62 , C09D7/67 , C09D7/68 , C09D7/69 , C09D125/06 , Y10T428/25 , Y10T428/254 , Y10T428/31551 , Y10T428/31569
摘要： The invention describes compositions that include a polymer having a water contact angle of between about 120° and about 150° or greater adhered to a 1 nm to about a 25 micron diameter sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
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公开(公告)号：EP2171135A2
公开(公告)日：2010-04-07
申请号：EP08780890.3
申请日：2008-06-20
发明人： NAQVI, Tahmina , WEN, Jie , GUIRE, Patrick
IPC分类号： D01D5/00 , D01F1/10 , D01F6/22 , D01F6/26 , D01F6/62 , D06M15/285 , A61L27/34 , A61L29/08 , A61L31/10 , C12M3/00 , C08F8/00
CPC分类号： C12N5/0068 , A61L27/16 , A61L27/34 , A61L27/50 , A61L27/54 , A61L29/041 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/048 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/00 , A61L2400/12 , C12M23/08 , C12M23/20 , C12M25/14 , C12N2533/30 , C12N2537/10 , C12N2539/00 , D01D5/0007 , D01F1/10 , D01F6/22 , D01F6/26 , D01F6/625 , D06M15/285 , D06M2400/01 , G01N33/48 , C08L33/26
摘要： A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.
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6.发明授权
公开(公告)号：EP1891022B1
公开(公告)日：2012-04-04
申请号：EP06773090.3
申请日：2006-06-13
发明人： GUIRE, Patirck , TATON, Kristin , WEN, Jie
IPC分类号： C07D251/34 , C07C275/10 , C07C49/784 , C07C49/786 , C08L37/00 , C08L67/00
CPC分类号： C07D251/30 , C07C275/10 , C07D251/34 , C09D139/08
摘要： The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
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公开(公告)号：EP2516567B1
公开(公告)日：2016-08-03
申请号：EP10842733.7
申请日：2010-12-21
发明人： WEN, Jie , TATON, Kristin , LAWIN, Laurie , KNOPKE, William , GUIRE, Eric , GUIRE, Patrick
IPC分类号： C09D173/02 , C09D133/02 , C09D139/06 , C08J7/06 , C09D135/08 , C09D201/02 , C09D131/00
CPC分类号： C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
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公开(公告)号：EP2331644A1
公开(公告)日：2011-06-15
申请号：EP09812195.7
申请日：2009-09-03
发明人： BLOOMQUIST, Timothy, A. , JOSEPHSON, Mark, W. , LAWIN, Laurie, R. , TATON, Kristin, S. , WEN, Jie
IPC分类号： C09D159/00 , A61L29/08 , A61L31/08
摘要： The invention describes novel compositions of crosslinkers that include at least two pendent photoactivatable groups, such as benzophenone moieties, and an initiator, such as acetophenone.
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公开(公告)号：EP2160484A2
公开(公告)日：2010-03-10
申请号：EP08771639.5
申请日：2008-06-20
发明人： WEN, Jie , GUIRE, Patrick
IPC分类号： D01D5/00 , D01F1/10 , D01F6/62 , D06M15/263 , D06M15/273 , D06M15/285 , A61L27/34 , A61L29/08 , A61L31/10 , C12M3/00 , C08F8/00
CPC分类号： D01D5/003 , A61L27/50 , A61L29/14 , A61L31/14 , A61L2400/12 , B05D3/067 , B29C35/08 , C12M23/20 , D01D5/0007 , D01F1/10 , D01F6/625 , D06M15/263 , D06M15/273 , D06M15/285 , D06M2400/01
摘要： A nanofiber is formed by combining one or more natural or synthetic polymeric materials and one or more than one cross-linking agents having at least two latent reactive activatable groups. The latent reactive activatable nanofiber may be used to modify the surface of a substrate by activating at least one of the latent reactive activatable groups to bond the nanofiber to the surface by the formation of a covalent bond between the surface of the substrate and the latent reactive activatable group. Some of the remaining latent reactive activatable group(s) are left accessible on the surface of the substrate, and may be used for further surface modification of the substrate. Biologically active materials may be immobilized on the nanofiber modified surface by reacting with the latent reactive groups that are accessible on the surface of the substrate.
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