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1.发明公开CELL USABLE IN SERUM-FREE CULTURE AND SUSPENSION CULTURE AND PROCESS FOR PRODUCING VIRUS FOR VACCINE BY USING THE CELL 有权在病毒生产无血清培养合适的细胞培养物悬浮液和方法作为疫苗使用细胞
公开(公告)号：EP1260581A1
公开(公告)日：2002-11-27
申请号：EP01908228.8
申请日：2001-03-02
IPC分类号： C12N5/06 , C12N7/00 , C07K14/005 , A61K39/12
CPC分类号： C12N5/0686 , A61K39/12 , C12N7/00 , C12N2500/92 , C12N2510/02 , C12N2710/16634 , C12N2760/16134 , C12N2760/16234 , C12N2760/18434 , C12N2760/18734 , C12N2770/36234
摘要： A novel MDCK-derived cell line (B-702) is provided that can be grown in the absence of fetal calf serum and in suspension culture for allowing a tank culture on the production scale and needs no carrier in suspension culture, as well as a process for producing virus for vaccine by using said cell line in a low-cost, highly safe and stable manner.
摘要翻译： 本发明提供一种新颖的MDCK衍生细胞系（B-702）也可以在不存在胎牛血清和在悬浮培养物中生长，以允许在生产规模的罐培养，无需载体在悬浮培养中，以及一个 用于通过使用所述细胞系在一个低成本，高安全性和稳定的方式制备用于疫苗病毒的过程。
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2.发明授权CELL USABLE IN SERUM-FREE CULTURE AND SUSPENSION CULTURE AND PROCESS FOR PRODUCING VIRUS FOR VACCINE BY USING THE CELL 有权在病毒生产无血清培养合适的细胞培养物悬浮液和方法作为疫苗使用细胞
公开(公告)号：EP1260581B1
公开(公告)日：2010-07-07
申请号：EP01908228.8
申请日：2001-03-02
IPC分类号： C12N5/07 , C12N7/00 , C07K14/005 , A61K39/12
CPC分类号： C12N5/0686 , A61K39/12 , C12N7/00 , C12N2500/92 , C12N2510/02 , C12N2710/16634 , C12N2760/16134 , C12N2760/16234 , C12N2760/18434 , C12N2760/18734 , C12N2770/36234
摘要： A novel MDCK cell-induction line (B-702) which can be cultured without using fetal bovine serum, has been suspended to enable tank culture on the production scale and requires no support in the suspended state; and a process for economically, highly safely and stably producing a virus for a vaccine by using the above cell.
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