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1.发明授权PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES 有权用于预防药物组合物及其与骨代谢ALPHA ARYLMETHOXYACRYLAT衍生物病证治疗
公开(公告)号：EP1784173B1
公开(公告)日：2012-01-18
申请号：EP05756853.7
申请日：2005-06-22
发明人： KIM, Bum Tae , MIN, Yong Ki , LEE, Yeon Soo , HEO, Jung Nyoung , LEE, Hyuk; , PARK, No Kyun , KIM, Jung-Keun, Hyojachon Hyundai Apt. 114-302 , KIM, Se-Won , KO, Seon-Yle
IPC分类号： A61K31/192 , A61P19/10
CPC分类号： A61K31/192
摘要： The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases.
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2.发明公开PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES 有权用于预防药物组合物及其与骨代谢ALPHA ARYLMETHOXYACRYLAT衍生物病证治疗
公开(公告)号：EP1784173A1
公开(公告)日：2007-05-16
申请号：EP05756853.7
申请日：2005-06-22
发明人： KIM, Bum Tae , MIN, Yong Ki , LEE, Yeon Soo , HEO, Jung Nyoung , LEE, Hyuk; , PARK, No Kyun , KIM, Jung-Keun, Hyojachon Hyundai Apt. 114-302 , KIM, Se-Won, Dujeong 5-cha Prugio Apt. 502-1304 , KO, Seon-Yle
IPC分类号： A61K31/192
CPC分类号： A61K31/192
摘要： The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases.
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公开(公告)号：EP3620457A1
公开(公告)日：2020-03-11
申请号：EP18794872.4
申请日：2018-05-02
发明人： CHO, Sung Yun , LEE, Chang Hoon , MIN, Yong Ki , HWANG, Jong Yeon
IPC分类号： C07D403/14 , A61K31/506 , A61K31/4725 , C07D401/14 , C07D239/48 , A61K31/505 , A23L33/10 , C07D403/04 , C07D413/14
摘要： The present invention relates to a pyrimidine derivative compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating cancer comprising the same as an active ingredient. The pyrimidine derivative compound, the optical isomer thereof, or the pharmaceutically acceptable salt thereof according to the present invention has an excellent selective inhibitory effect especially against TYRO 3 among TAM receptor inhibitory effects, and thus can be used as an excellent composition of preventing or treating cancer without adverse effects resulting from the inhibition of Axl and Mer.
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4.发明公开COMPOSITION FOR THE PREVENTION OR TREATMENT OF BONE DISEASES COMPRISING COLFORSIN DAROPATE 有权组成预防和骨病治疗COLFORSIN，DAROPAT
公开(公告)号：EP2455079A2
公开(公告)日：2012-05-23
申请号：EP10800063.9
申请日：2010-07-16
申请人： Korea Research Institute of Bioscience and Biotechnology , Korea Research Institute Of Chemical Technology
IPC分类号： A61K31/352 , A61P19/10 , A61P19/02 , A23L1/30
CPC分类号： A61K31/352 , A23L33/10 , A61K31/35
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of bone diseases comprising colforsin daropate, and more particularly, the present invention relates to a pharmaceutical composition for the prevention or treatment of bone diseases such as bone fracture and osteoporosis, which inhibits osteoclast differentiation and bone resorption caused by osteoclasts and promotes osteoblast differentiation and the activity of osteoblasts, and a health functional food composition comprising colforsin daropate.
摘要翻译： 本发明涉及一种用于预防或治疗骨疾病的药物组合物，包含colforsin daropate，并且更具体地，本发明涉及用于预防或治疗骨疾病的药物组合物：如骨骨折和骨质疏松症，其抑制破骨细胞 分化和破骨细胞骨再吸收和所致促进成骨细胞分化和成骨细胞的活性，以及功能保健食品组合物，包括colforsin daropate。
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5.发明授权COMPOSITION FOR THE PREVENTION OR TREATMENT OF BONE DISEASES COMPRISING COLFORSIN DAROPATE 有权组成预防和骨病治疗COLFORSIN，DAROPAT
公开(公告)号：EP2455079B1
公开(公告)日：2015-03-18
申请号：EP10800063.9
申请日：2010-07-16
申请人： Korea Research Institute of Bioscience and Biotechnology , Korea Research Institute Of Chemical Technology
CPC分类号： A61K31/352 , A23L33/10 , A61K31/35
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6.发明公开
公开(公告)号：EP2167490A1
公开(公告)日：2010-03-31
申请号：EP08766243.3
申请日：2008-06-12
发明人： KIM, Bum Tae , MIN, Yong Ki , HEO, Jung Nyoung , LEE, Hyuk , CHANG, Sung Youn , PARK, No Kyun , SONG, Si-Whan , OH, Jung-Ja
IPC分类号： C07D401/14
CPC分类号： C07D413/12 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14 , C07D417/12 , C07D513/04
摘要： A triazole derivative of formula 1 or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof is superior to the conventional antifungal drugs in antifungal activity against a wide spectrum of pathogenic fungi, and has advantageously low toxicity.
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7.发明公开
公开(公告)号：EP1654254A1
公开(公告)日：2006-05-10
申请号：EP04748524.8
申请日：2004-08-09
发明人： KIM, Bum Tae , MIN, Yong Ki , LEE, Yeon Soo , PARK, No Kyun , KIM, Woo Jung
IPC分类号： C07D403/06
CPC分类号： C07D403/06 , C07D231/12 , C07D233/56 , C07D249/08
摘要： An azole derivative of formula (I) having a fluorovinyl moiety or a pharmaceutically acceptable salt thereof is superior to the conventional antifungal drugs in antifungal activity against a wide spectrum of pathogenic fungi, and has advantageously low toxicity.
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