公开(公告)号：EP0566427A3

公开(公告)日：1994-06-15

申请号：EP93302969.6

申请日：1993-04-16

申请人： KYOCERA CORPORATION

发明人： Hamamoto, Schoici, Kyocera Corp, Kyoto Karasuma Of ,  Amino, Hirokazu, c/o Kyocera Corporation, Mitsui ,  Ishida, Noriyuki, c/o Kyocera Corporation, Mitsui ,  Tamura, Yasunori, c/o Kyocera Corporation ,  Nishio, Yoichi, c/o Kyocera Corp., Mitsui Seimei

IPC分类号： A61F2/30 ,  A61L27/00 ,  B22F7/00 ,  A61F2/28

CPC分类号： A61F2/30907 ,  A61C8/0012 ,  A61F2/28 ,  A61F2/30 ,  A61F2/30734 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/367 ,  A61F2/44 ,  A61F2002/30112 ,  A61F2002/30158 ,  A61F2002/30261 ,  A61F2002/30433 ,  A61F2002/30441 ,  A61F2002/30785 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/30929 ,  A61F2002/30971 ,  A61F2002/3605 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0026 ,  A61F2230/0082 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/56

摘要： A prosthesis for the replacement of hard tissues of human bones and joints, comprising a porous lamination component of metal thin sheets, each having a plurality of through holes and a thickness of 150 µm or less, and being unharmful to the living body, the porous lamination component being formed such that the sheets are laid over one another and are then diffusion-bonded therebetween into one body by heating so that the through holes communicate with one another in the direction of the thickness thereof, and the prosthesis being entirely or partially composed of the porous lamination component. The present invention also relates to a method of making such a prosthesis. The present invention can provide prostheses which are not required to be replaced again, thereby imposing a less burden to patients.

公开(公告)号：EP0566427A2

公开(公告)日：1993-10-20

申请号：EP93302969.6

申请日：1993-04-16

申请人： KYOCERA CORPORATION

发明人： Hamamoto, Schoici, Kyocera Corp, Kyoto Karasuma Of ,  Amino, Hirokazu, c/o Kyocera Corporation, Mitsui ,  Ishida, Noriyuki, c/o Kyocera Corporation, Mitsui ,  Tamura, Yasunori, c/o Kyocera Corporation ,  Nishio, Yoichi, c/o Kyocera Corp., Mitsui Seimei

IPC分类号： A61F2/30 ,  A61L27/00 ,  B22F7/00 ,  A61F2/28

CPC分类号： A61F2/30907 ,  A61C8/0012 ,  A61F2/28 ,  A61F2/30 ,  A61F2/30734 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/367 ,  A61F2/44 ,  A61F2002/30112 ,  A61F2002/30158 ,  A61F2002/30261 ,  A61F2002/30433 ,  A61F2002/30441 ,  A61F2002/30785 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/30929 ,  A61F2002/30971 ,  A61F2002/3605 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0026 ,  A61F2230/0082 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/56

摘要： A prosthesis for the replacement of hard tissues of human bones and joints, comprising a porous lamination component of metal thin sheets, each having a plurality of through holes and a thickness of 150 µm or less, and being unharmful to the living body, the porous lamination component being formed such that the sheets are laid over one another and are then diffusion-bonded therebetween into one body by heating so that the through holes communicate with one another in the direction of the thickness thereof, and the prosthesis being entirely or partially composed of the porous lamination component. The present invention also relates to a method of making such a prosthesis.
The present invention can provide prostheses which are not required to be replaced again, thereby imposing a less burden to patients.

摘要翻译： 一种用于更换人骨和关节的硬组织的假体，包括金属薄片的多孔层压部件，每个具有多个通孔并且厚度为150μm或更小，并且对生物体不伤害， 多孔层压部件被形成为使得片材彼此铺设并且然后通过加热将它们扩散粘合成一体，使得通孔在其厚度方向上彼此连通，并且假体完全或部分地 由多孔层压部件组成。 本发明还涉及一种制造这种假体的方法。 本发明可以提供不需要再次更换的假体，从而对患者施加较少的负担。

公开(公告)号：EP0566427B1

公开(公告)日：2000-03-15

申请号：EP93302969.6

申请日：1993-04-16

申请人： KYOCERA CORPORATION

发明人： Hamamoto, Schoici, Kyocera Corp, Kyoto Karasuma Of ,  Amino, Hirokazu, c/o Kyocera Corporation, Mitsui ,  Ishida, Noriyuki, c/o Kyocera Corporation, Mitsui ,  Tamura, Yasunori, c/o Kyocera Corporation ,  Nishio, Yoichi, c/o Kyocera Corp., Mitsui Seimei

IPC分类号： A61F2/30 ,  A61L27/00 ,  B22F7/00 ,  A61F2/28

CPC分类号： A61F2/30907 ,  A61C8/0012 ,  A61F2/28 ,  A61F2/30 ,  A61F2/30734 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/367 ,  A61F2/44 ,  A61F2002/30112 ,  A61F2002/30158 ,  A61F2002/30261 ,  A61F2002/30433 ,  A61F2002/30441 ,  A61F2002/30785 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/30929 ,  A61F2002/30971 ,  A61F2002/3605 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0026 ,  A61F2230/0082 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/56

摘要： A prosthesis for the replacement of hard tissues of human bones and joints, comprising a porous lamination component of metal thin sheets, each having a plurality of through holes and a thickness of 150 mu m or less, and being unharmful to the living body, the porous lamination component being formed such that the sheets are laid over one another and are then diffusion-bonded therebetween into one body by heating so that the through holes communicate with one another in the direction of the thickness thereof, and the prosthesis being entirely or partially composed of the porous lamination component. The present invention also relates to a method of making such a prosthesis. The present invention can provide prostheses which are not required to be replaced again, thereby imposing a less burden to patients.

公开(公告)号：EP0621018A1

公开(公告)日：1994-10-26

申请号：EP93305669.9

申请日：1993-07-19

申请人： KYOCERA CORPORATION

发明人： Hamamoto, Schoici, Kyocera Corp., Eisen Karasuma ,  Amino, Hirokazu, Kyocera Corp., Mitsui Seimei ,  Ishida, Noriyuki, Kyocera Corp., Mitsui Seimei ,  Tamura, Yasunori, c/o Kyocera Corporation ,  Nishio, Yoichi, Kyocera Corp., Mitsui Seimei ,  Ichimiya, Masaru, c/o Kyocera Corporation

IPC分类号： A61F2/28 ,  A61F2/32

CPC分类号： A61F2/30907 ,  A61C8/0012 ,  A61F2/28 ,  A61F2/30 ,  A61F2/30734 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/367 ,  A61F2/44 ,  A61F2002/30112 ,  A61F2002/30158 ,  A61F2002/30261 ,  A61F2002/30433 ,  A61F2002/30441 ,  A61F2002/30785 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/30929 ,  A61F2002/30971 ,  A61F2002/3605 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0026 ,  A61F2230/0082 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/56

摘要： A prosthesis for the replacement of hard tissues of human bones and joints, comprises a porous lamination component of metal thin sheets, each having a plurality of through holes and a thickness of 150 µm or less, and being of a metal unharmful to the living body selected from titanium alloy, Co-Cr-Mo alloy or Fe-Ni-Cr alloy, the porous lamination component being formed such that the sheets are laid over one another and are then diffusion-bonded therebetween into one body by heating so that the through holes communicate with one another in the direction of the thickness thereof, especially wherein a single hole formed in at least one of a pair of said thin sheets being vertically adjacent to each other communicates with a plurality of holes formed in the other of the pair in the plan view direction of said thin sheets, and the prosthesis is entirely or partially composed of the porous lamination component. Such prostheses are not required to be replaced again, thereby imposing a lesser burden on patients.

摘要翻译： 用于替代人骨和关节的硬组织的假体包括金属薄片的多孔层压部件，每个多孔层压部件具有多个通孔，厚度为150μm或更小，并且是对生命无害的金属 主体选自钛合金，Co-Cr-Mo合金或Fe-Ni-Cr合金，多孔层压部件形成为使得片材彼此铺设，然后通过加热将它们扩散粘结成一体， 通孔在其厚度方向上彼此连通，特别是其中形成在彼此垂直相邻的一对所述薄片中的至少一个中形成的单个孔与形成在该对中的另一个中的多个孔连通 在所述薄片的平面视图方向上，并且所述假体完全或部分地由所述多孔层压部件构成。 这样的假体不需要再次替换，从而对患者施加较小的负担。

公开(公告)号：EP0591976B1

公开(公告)日：2000-03-29

申请号：EP93116261.4

申请日：1993-10-07

申请人： KYOCERA CORPORATION

发明人： Okimatsu, Hideaki, c/o Kyocera Corporation ,  Tamura, Yasunori, c/o Kyocera Corporation

IPC分类号： A61L27/00 ,  A61L31/00 ,  A61F2/28

CPC分类号： A61L31/022 ,  A61F2/28 ,  A61F2/30907 ,  A61F2/30965 ,  A61F2002/30263 ,  A61F2002/30968 ,  A61F2230/0084 ,  A61F2310/00023 ,  A61L27/04 ,  A61L27/06 ,  A61L27/56 ,  A61L31/146 ,  Y10T428/12035

摘要： A porous living body repairing member obtained by compressionmolding a metal fiber material into a desired shape, sintering the fiber mesh body, or thereafter, imparting a compressive stress of not more than 4.00 to 40.0 MPa to provide a porous living body repairing member having a compressive elasticity of not more than 2000 MPa and a permanent deformation of not more than 1 % under a stress below the compressive yield stress. When the porous living body repairing member is used at a high compressive load site such as man's lumbar body, permanent deformation hardly occours. When said member is transplanted within the living body, its stress to the bone is well transmitted, and it acts advantageously to the bone ingrowth in the pore. At the same time, bone absorption around the repairing member is not developed.

公开(公告)号：EP0621018B1

公开(公告)日：1999-09-15

申请号：EP93305669.9

申请日：1993-07-19

申请人： KYOCERA CORPORATION

发明人： Hamamoto, Schoici, Kyocera Corp., Eisen Karasuma ,  Amino, Hirokazu, Kyocera Corp., Mitsui Seimei ,  Ishida, Noriyuki, Kyocera Corp., Mitsui Seimei ,  Tamura, Yasunori, c/o Kyocera Corporation ,  Nishio, Yoichi, Kyocera Corp., Mitsui Seimei ,  Ichimiya, Masaru, c/o Kyocera Corporation

IPC分类号： A61F2/28 ,  A61F2/32

CPC分类号： A61F2/30907 ,  A61C8/0012 ,  A61F2/28 ,  A61F2/30 ,  A61F2/30734 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/367 ,  A61F2/44 ,  A61F2002/30112 ,  A61F2002/30158 ,  A61F2002/30261 ,  A61F2002/30433 ,  A61F2002/30441 ,  A61F2002/30785 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/30929 ,  A61F2002/30971 ,  A61F2002/3605 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0026 ,  A61F2230/0082 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/56

摘要： A prosthesis for the replacement of hard tissues of human bones and joints, comprising a porous lamination component of metal thin sheets, each having a plurality of through holes and a thickness of 150 mu m or less, and being unharmful to the living body, the porous lamination component being formed such that the sheets are laid over one another and are then diffusion-bonded therebetween into one body by heating so that the through holes communicate with one another in the direction of the thickness thereof, and the prosthesis being entirely or partially composed of the porous lamination component. The present invention also relates to a method of making such a prosthesis. The present invention can provide prostheses which are not required to be replaced again, thereby imposing a less burden to patients.

公开(公告)号：EP0591976A1

公开(公告)日：1994-04-13

申请号：EP93116261.4

申请日：1993-10-07

申请人： KYOCERA CORPORATION

发明人： Okimatsu, Hideaki, c/o Kyocera Corporation ,  Tamura, Yasunori, c/o Kyocera Corporation

IPC分类号： A61L27/00 ,  A61L31/00 ,  A61F2/28

CPC分类号： A61L31/022 ,  A61F2/28 ,  A61F2/30907 ,  A61F2/30965 ,  A61F2002/30263 ,  A61F2002/30968 ,  A61F2230/0084 ,  A61F2310/00023 ,  A61L27/04 ,  A61L27/06 ,  A61L27/56 ,  A61L31/146 ,  Y10T428/12035

摘要： A porous living body repairing member obtained by compressionmolding a metal fiber material into a desired shape, sintering the fiber mesh body, or thereafter, imparting a compressive stress of not more than 4.00 to 40.0 MPa to provide a porous living body repairing member having a compressive elasticity of not more than 2000 MPa and a permanent deformation of not more than 1 % under a stress below the compressive yield stress. When the porous living body repairing member is used at a high compressive load site such as man's lumbar body, permanent deformation hardly occours. When said member is transplanted within the living body, its stress to the bone is well transmitted, and it acts advantageously to the bone ingrowth in the pore. At the same time, bone absorption around the repairing member is not developed.

摘要翻译： 通过compressionmolding金属纤维材料成所需的形状，烧结所述纤维网状体，或在其后，赋予不超过4:00的压缩应力获得40.0兆帕的多孔生物体修补构件，以提供具有压缩的多孔生物体修理部件 不超过2000兆帕的弹性和不超过1％的压缩屈服应力以下的应力下永久变形。 当多孔生物体修理部件用于在高压缩载荷站点：如人的腰椎体，永久变形几乎不occours。 当所述部件在生物体内移植，其应力到骨是公反mitted，并且其有利地起作用以在所述孔的骨向内生长。 在Sametime中周围的修复体骨的吸收并不发达。