公开(公告)号：EP2473625A2

公开(公告)日：2012-07-11

申请号：EP10760014.0

申请日：2010-08-26

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  FEITSMA, Harma, Martine ,  DEN TOONDER, Jacob, Marinus, Jan ,  WIMBERGER-FRIEDL, Reinhold

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6834 ,  C12Q2537/149 ,  C12Q2527/107

摘要： The present invention relates to a device for the specific selection of target molecules, wherein immobilized capture molecules can be organized in a microarray in the form of spots or lines. In a further aspect the present invention relates to a method of specifically selecting target molecules in a reaction zone, as well as the use of such a device for specifically selecting target molecules, e.g. for target enrichment, or microarray based genome selection (MGS).

公开(公告)号：EP0910800B1

公开(公告)日：2004-02-11

申请号：EP97923275.8

申请日：1997-06-06

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  MUNSTERS, Hendrik, Theodorus

IPC分类号： G01R33/02

CPC分类号： B82Y25/00 ,  G01R33/093 ,  Y10S428/90 ,  Y10T428/1121

摘要： A method of manufacturing a magnetic field sensor having a stacked structure which comprises: a substrate (1); an exchange-biasing layer (2) comprising nickel oxide; a magnetic layer (3) which is exchange-biased with the exchange-biasing layer (2), whereby at least the exchange-biasing layer (2) is provided by sputter deposition using a sputter gas which comprises Ne and/or He. The magnetic layer (3) preferably comprises permalloy. In a particular embodiment, the magnetic layer (3) is separated from a second magnetic layer (5) by an interposed non-magnetic layer (4), so as to form a spin-valve trilayer.

公开(公告)号：EP2636003A2

公开(公告)日：2013-09-11

申请号：EP11785483.6

申请日：2011-10-24

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  DIMITROVA, Nevenka ,  VAN DE STOLPE, Anja ,  VAN HOUTEN, Hendrik

IPC分类号： G06Q10/00 ,  C12Q1/68 ,  G06F19/00

CPC分类号： G06Q20/10 ,  G06Q10/00 ,  G06Q50/22 ,  G16B20/00 ,  G16H40/20 ,  G16H40/63

摘要： A method comprises: recording an electronic record of diagnostic events including the performing of in-vitro diagnostic tests; during the recording, identifying the performing of a licensed in-vitro diagnostic test for which license information is stored in a licenses database; and computing license compensation due to a licensor for the performing of the licensed in-vitro diagnostic test based on royalty calculation information stored in the licenses database. The recording, identifying, and computing operations are performed by one or more computers. The method may further include remitting the computed license compensation to the licensor, the remitting also being performed by one or more computers. The licensed in-vitro diagnostic test may comprise a licensed biomarker test, for example one obtained by DNA or RNA sequencing, and the method may further comprise: performing the licensed biomarker test using a genome sequencer, wherein the performing of the licensed biomarker test and the computing of license compensation are both performed at a single medical facility.

公开(公告)号：EP2611939A1

公开(公告)日：2013-07-10

申请号：EP11764308.0

申请日：2011-08-31

申请人： Koninklijke Philips Electronics N.V.

发明人： FEITSMA, Harma, Martine ,  OVERDIJK, Marlieke, Joan ,  VAN DE STOLPE, Anja ,  VAN DER ZAAG, Pieter, Jan

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6869 ,  C12Q1/6837 ,  C12Q1/6874 ,  C12Q2565/543 ,  C12Q2525/301

摘要： The present invention describes methods for amplifying a target nucleic acid wherein target nucleic acids hybridise to capture probe nucleic acids wich are immobilized to a support via their 5' end. The hybridization product is further extended with a polymerase to form a double stranded nucleic acid. To this double stranded nucleic acid, a hairpin nucleic acid is ligated. This ligation product is further amplified and sequenced.

摘要翻译： 本发明描述了用于扩增目标核酸的方法，其中靶核酸通过其5'端捕获固定在载体上的探针核酸杂交。 进一步用聚合酶扩增杂交产物以形成双链核酸。 向该双链核酸中连接发夹核酸。 该连接产物进一步扩增和测序。

公开(公告)号：EP1955074A2

公开(公告)日：2008-08-13

申请号：EP06821496.4

申请日：2006-11-20

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  BAKKERS, Erik, Petrus, Antonius, Maria ,  VAN DER MARK, Martinus, Bernardus

IPC分类号： G01N33/58

CPC分类号： G01N33/588 ,  B82Y15/00 ,  G01N33/533

摘要： The invention provides a luminescent particle (10) and a method of detecting a biological entity using a luminescent particle, the luminescent particle comprising a core area (20) and a shell area (30), the core area (20) being covered by the shell area (30), the core area (20) conferring a luminescent behavior on the luminescent particle (10) for at least one excitation wavelength and for at least one emission wavelength by means of a nanocrystal material (21), and the shell area (30) being provided such that it realizes an antireflective coating (31) of the core area (20).

公开(公告)号：EP0739324B1

公开(公告)日：1999-03-24

申请号：EP95933600.9

申请日：1995-10-26

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  VAN DER VALK, Pieter, Johan

IPC分类号： C04B35/26

CPC分类号： H01F1/10 ,  C04B35/2633 ,  H01F1/348

摘要： The invention relates to a moulding of a sintered hexagonal ferrite material. This moulding is characterized in that the majority of the grains of the material have a monodomain structure. By virtue thereof, the loss factor tan delta of this material is much smaller than that of corresponding known materials if said material is used in the frequency range of 100 MHz or higher. The monodomain structure of this material is obtained, in particular, if the average grain size of the material is smaller than 2.8 micrometers. The average grain size preferably ranges between 1.4 micrometers and 2.5 micrometers. Preference is given, in particular, to those ferrite materials whose composition corresponds to the formula Ba3Me2Fe24O41, wherein Me stands for one or more divalent ions selected from the group formed by Co, Fe, Mn, Ni, Zn, Mg and (Li.Fe)1/2. Even at very high frequencies, these materials exhibit a small loss factor. The mouldings in accordance with the invention are extremely suitable for use in antennas.

公开(公告)号：EP2475459A1

公开(公告)日：2012-07-18

申请号：EP10760045.4

申请日：2010-09-06

申请人： Koninklijke Philips Electronics N.V.

发明人： DEN TOONDER, Jacob Marinus Jan ,  VAN DER ZAAG, Pieter, Jan ,  CHAO, Hao, Chieh

IPC分类号： B01L3/00 ,  B01F13/00 ,  G01N35/00

CPC分类号： B03C1/034 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2400/043 ,  B03C1/0335 ,  B03C1/24 ,  B03C2201/18

摘要： The present invention relates to a device (24) for transporting magnetic or magnetisable beads (10) over a transport surface (12). It comprises a chamber (26) comprising magnetic or magnetisable beads (10) in a fluid (28), a transport element (14) including said transport surface (12) within said chamber (26) over which said beads (10) shall be transported, a current wire structure (20) comprising at least two sets (20a, 20b, 20c) of meandering current wires arranged on a side of said transport element (14) opposite to said transport surface (12), said at least two sets (20a, 20b, 20c) being displaced with respect to each other in at least two directions, and a switching unit (32) for individually switching currents (1a, 1b, 1c) individually applied to said sets of current wires according to a current driving scheme resulting in a transport of said beads (10) over said transport surface (12). In preferred embodiments a stationary substantially uniform magnetic field (30) in a direction substantially parallel to the transport surface (12) is additionally provided.

公开(公告)号：EP0818038B1

公开(公告)日：2003-06-18

申请号：EP97900088.2

申请日：1997-01-20

申请人： Koninklijke Philips Electronics N.V.

发明人： RUIGROK, Jacobus, Josephus, Maria ,  VAN DER ZAAG, Pieter, Jan

IPC分类号： G11B5/39

CPC分类号： G11B5/3916 ,  G11B5/3925 ,  G11B5/3932

摘要： Magnetic head having a head face (1) and comprising a multilayer structure with a flux guide (7a, 7b), a magnetoresistive sensor (9) and an intermediate layer (13) present between the flux guide and said sensor. The intermediate layer comprises an anti-ferromagnetic oxide which insulates the sensor from the flux guide and also magnetically biases the sensor.

公开(公告)号：EP0738422B1

公开(公告)日：2001-10-04

申请号：EP95933594.4

申请日：1995-10-25

申请人： Koninklijke Philips Electronics N.V.

发明人： VAN DER ZAAG, Pieter, Jan ,  VAN DER VALK, Pieter, Johan ,  DE WIT, Hendrik, Jan

IPC分类号： H01J29/76 ,  C04B35/26 ,  H01F1/34

CPC分类号： H01F41/0246 ,  C04B35/2683 ,  H01F2041/0711 ,  H01J29/76 ,  H01J2229/7031

摘要： The invention relates to a deflection ring of sintered MgZn-ferrite material. In accordance with the invention, this deflection ring is characterized in that the majority of the grains of the sintered material have a monodomain structure. By virtue thereof, a relatively small heat dissipation occurs in the ring when it is used in a cathode ray tube. The average grain size of the sintered MgZn-ferrite material is preferably 2.8 micrometers or less. MgZn-ferrite materials whose composition corresponds to the formulaMg1-zZnzFe2-yO4, wherein 0.1

公开(公告)号：EP0948788A1

公开(公告)日：1999-10-13

申请号：EP98945491.0

申请日：1998-10-12

申请人： Koninklijke Philips Electronics N.V.

发明人： RUIGROK, Jacobus, Josephus, Maria ,  COEHOORN, Reinder ,  VAN DER ZAAG, Pieter, Jan

IPC分类号： G01R33 ,  G11B5

CPC分类号： B82Y25/00 ,  G01R33/093 ,  G01R33/098 ,  G11B5/332 ,  G11B5/3903 ,  G11B5/3919 ,  G11B5/3922

摘要： A magnetic field sensor comprising a transducer element (1), whereby: (I) the transducer element (1) is a Spin Tunnel Junction, comprising a first (1a) and second (1b) magnetic layer which are sandwiched about an interposed electrical insulator layer (1c); (II) the sensor comprises a yoke (3) having two arms (3a, 3b); (III) the first magnetic layer (1a) is in direct contact with a first portion of a first arm (3a) of the yoke (3).