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1.发明公开A DEVICE FOR AND A METHOD OF ACTIVATING A PHYSIOLOGICALLY EFFECTIVE SUBSTANCE BY ULTRASONIC WAVES, AND A CAPSULE 审中-公开装置和方法一种有效的生物体内成分BY超声波及胶囊激活
公开(公告)号：EP2051776A2
公开(公告)日：2009-04-29
申请号：EP07805332.9
申请日：2007-08-07
IPC分类号： A61N7/00
CPC分类号： A61M37/0092 , A61N7/00 , A61N2007/0078
摘要： A device (100) for activating a physiologically effective substance (101) by ultrasonic waves (103, 105), the device comprising an ultrasonic transducer (102) adapted to generate ultrasonic waves (103), a focusing element (104) adapted to focus the generated ultrasonic waves (103), and an adjustment unit (107) adapted to adjust a position (106) to which the focusing element (105) focuses the generated ultrasonic waves (103) in a manner that the focused ultrasonic waves (103) are bringable in interaction with the physiologically effective substance (101) at the adjusted position (106).
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公开(公告)号：EP2477553A1
公开(公告)日：2012-07-25
申请号：EP10760774.9
申请日：2010-09-15
IPC分类号： A61B8/08
CPC分类号： A61B8/08 , A61B8/0883 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/546 , A61B18/1206 , A61B18/1492 , A61B2018/00702 , A61B2018/00791 , A61B2090/3782 , A61N2007/0078 , G01K11/24 , G01K13/002 , G01K2217/00
摘要： A medical ultrasound device is disclosed. The device comprises an elongated body having a proximal end, a distal end (10) and a distal end region (1). One or more ultrasound transducers (4) for generating acoustic radiation are positioned in the distal end region, inside the elongated body. A transmission element (5) which is substantially transparent to acoustic radiation is positioned in the radiation path of the acoustic radiation, and a controller unit is operatively connected to the ultrasound transducer. The controller unit detects the acoustic path length through the transmission element and determines the temperature at the distal end from the detected acoustic path length. In an embodiment, the medical device is an ultrasound RF ablation catheter.
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公开(公告)号：EP2147428A1
公开(公告)日：2010-01-27
申请号：EP08738048.1
申请日：2008-04-30
发明人： HALL, Christopher Stephen , CHIN, Chien Ting , SUIJVER, Jan Frederik , HENDRIKS, Bernardus Hendrikus Wilhelmus , KUIPER, Stein
IPC分类号： G10K11/30
CPC分类号： G10K11/30
摘要： An acoustic probe (100, 300) includes an acoustic transducer (15, 444), and a plurality of variably-refracting acoustic lens elements (10, 210a, 210b, 442) coupled to the acoustic transducer. Each variably-refracting acoustic lens element has at least a pair of electrodes (150, 160) adapted to adjust at least one characteristic of the variably-refracting acoustic lens element in response to a selected voltage applied across the electrodes. In one embodiment, each variably-refracting acoustic lens element includes a cavity, first and second fluid media (141, 142) disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.
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公开(公告)号：EP2051623A2
公开(公告)日：2009-04-29
申请号：EP07805310.5
申请日：2007-08-06
CPC分类号： G01S17/58 , A61B5/027 , G01S7/4811 , G02B6/2726 , G02B6/2773
摘要： The invention relates to a light-emitting apparatus (100) comprising an optical waveguide, particularly an optical fiber (1), for guiding a primary light beam (Bprim) into a light-splitting unit (101) which splits it into two or more partial light beams (Bl, B3, B4) which are emitted in different directions and have different optical qualities, e.g. different spectral compositions or polarizations. The apparatus may optionally comprise a detector (4) for determining a Doppler shift (Δλi) in reflected light reentering the light-splitting unit (101). This renders it possible to measure simultaneously two or more spatially independent vector components of the flow velocity of a fluid, particularly of blood, surrounding the light-splitting unit (101).
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5.发明公开CATHETER WITH ULTRASOUND TRANSDUCER AND VARIABLE FOCUS LENS USED IN ANEURYSM ASSESSMENT 审中-公开与超声波换能器和镜头变焦评估动脉瘤的导管
公开(公告)号：EP2099365A1
公开(公告)日：2009-09-16
申请号：EP07849170.1
申请日：2007-11-16
CPC分类号： A61B8/12 , A61B5/02014 , A61B8/06 , A61B8/445 , A61B8/4483 , A61B8/483 , A61B17/12113 , A61B17/1214 , A61B2017/1205 , G10K11/30
摘要： A catheter having ultrasound capability and a distal end extending along a longitudinal axis, the end being situated adjacent to a tissue of interest inside of a patient; at least one ultrasound transducer located in the end to direct ultrasound waves along the axis in a generally forward direction relative to the end; a variable-focus lens system located in the end, downstream of the transducer in the generally forward direction, the lens system being capable of variably focusing the ultrasound waves emitted by the transducer at various positions downstream of the lens and catheter end; optionally, a mirror located in the end, downstream of the transducer and the lens system in the generally forward direction, whereby the emitted ultrasound waves from the lens system are either reflected from the mirror and focused at a position substantially perpendicular to the longitudinal axis; or the emitted ultrasound waves from the lens system substantially bypass the mirror in unreflected form and are focused at a position downstream of the transducer, the lens system and the mirror in the generally forward direction along the longitudinal axis; and imaging means for translating the focused ultrasound waves from the lens system reflected and/or unreflected by the mirror into three-dimensional images and communicating the images in viewable form to a human operator that is external to the patient. A method of measuring, imaging and viewing blood flow velocity and patterns in a blood vessel and aneurysm, as well as monitoring vaso-occlusive coil placement in an aneurysm during a surgical intervention using the catheter, is also disclosed.
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6.发明公开
公开(公告)号：EP2020897A2
公开(公告)日：2009-02-11
申请号：EP07735731.7
申请日：2007-05-02
IPC分类号： A61B1/00
CPC分类号： G02B6/06 , A61B1/00167 , A61B1/00193 , G02B6/0008 , G02B6/04 , G02B23/2469 , H04N5/2256 , H04N5/2257 , H04N5/372 , H04N2005/2255
摘要： The invention relates to an imaging system and a method for three- dimensional imaging of the interior of an object. The imaging system comprises illumination means (10), detection means (11) and reconstruction means. The illumination means is adapted to illuminate the interior of the object with light, wherein the illumination means (10) is capable of generating different spatial light intensity distributions on the interior of the object. The detection means (11) is adapted to detect the different spatial light intensity distributions, and the reconstruction means is adapted to reconstruct a three-dimensional image from the detected different spatial light intensity distributions. The invention relates further to an optical fiber system comprising a transfer mechanism to transfer the optical fiber system from a first condition, in which optical fibers diverge from each other, to a second condition, in which optical fibers are parallel to each other, and vice versa.
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公开(公告)号：EP2525717A1
公开(公告)日：2012-11-28
申请号：EP11702709.4
申请日：2011-01-12
CPC分类号： A61B8/12 , A61B5/0084 , A61B6/032 , A61B6/12 , A61B6/5247 , A61B8/445 , A61B8/4483 , A61B8/5238 , A61B10/0233 , G01S15/8952
摘要： The invention relates to an imaging apparatus (1) for imaging an interior of an object (2). The imaging apparatus (1) comprises a first ultrasound sensor and a second ultrasound sensor for sensing the interior of the object at different frequencies, wherein the ultrasound sensing signals from the first ultrasound sensor are used for generating a first ultrasound image and a the ultrasound sensing signals from the second ultrasound sensor are used for generating a second ultrasound image. A larger frequency generally provides a smaller depth of penetrating the interior of the object and a larger spatial resolution than a smaller frequency. The imaging apparatus (1) can therefore provide the capability of simultaneously imaging the interior of the object with different spatial resolutions and at different penetration depths. This allows the imaging apparatus to improve the quality of imaging the interior of the object.
摘要翻译： 本发明涉及用于对物体（2）的内部进行成像的成像装置（1）。 成像设备（1）包括第一超声波传感器和第二超声波传感器，用于以不同频率感测对象的内部，其中来自第一超声波传感器的超声感测信号被用于生成第一超声图像并且超声感测 来自第二超声波传感器的信号被用于生成第二超声波图像。 较大的频率通常提供穿透物体内部的较小深度以及比较小频率更大的空间分辨率。 因此成像装置（1）可以提供以不同的空间分辨率和不同的穿透深度同时成像物体内部的能力。 这允许成像装置改善对物体内部成像的质量。
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8.发明授权DIAGNOSTIC SYSTEMS AND METHODS UTILIZING PROBE-IONS EXHIBITING PHOTON AVALANCHE EFFECT 有权诊断系统和方法，包括探头离子与光子雪崩效应
公开(公告)号：EP2001520B1
公开(公告)日：2012-08-08
申请号：EP07735175.7
申请日：2007-03-19
IPC分类号： A61K49/00
CPC分类号： A61K49/0067 , B82Y5/00
摘要： The present disclosure provides advantageous systems and methods for significantly increasing the sensitivity and selectivity for diagnostic procedures, e.g., optical biopsy. The disclosed systems and methods use a highly non-linear effect, the so- called photon avalanche. In the regime close to the avalanche threshold, small differences in density of the probe-ion under investigation or the excitation power can result in very large changes in up-conversion emission intensity. Through this effect, it becomes possible to accurately measure the signal of an optical biopsy probe-ion only in the location(s) where its concentration is highest, while at the same time significantly reducing or eliminating measurement of background signal from probe- ions distributed with a somewhat lower concentration throughout the measurement volume. Also background auto -fluorescence of the surrounding healthy tissue is essentially absent with this technique.
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9.发明公开
公开(公告)号：EP2057624A2
公开(公告)日：2009-05-13
申请号：EP07735490.0
申请日：2007-04-12
IPC分类号： G10K11/30
CPC分类号： G10K11/30
摘要： An acoustic device is disclosed having a variably refracting acoustic fluid interface (100) including the boundary between two separate fluid media (1, 2), means for directing acoustic waves (2) onto the interface, and an acoustic generator or transducer located (31) in one of the fluid media with the acoustic generator having an impedance that is substantially equal to the one said fluid media to minimize signal loss and reflection.
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公开(公告)号：EP2475401A2
公开(公告)日：2012-07-18
申请号：EP10760035.5
申请日：2010-09-02
IPC分类号： A61L2/04
摘要： The invention relates to a sterilization coat (1) for sterilizing a device (2) like a medical detection device, wherein the sterilization coat (1) is adapted to be arranged on the device (2) and comprises a heating layer for sterilizing the device (2) by heating. If the sterilization coat (1) has been arranged on the device, several sterilization procedures can be performed by heating the sterilization coat (1) using the heating layer. Thus, it is not necessary to arrange sterile plastic drapes around the device (2) each time a sterile device is needed, for example, before each medical interventional procedure. If a sterilization of the device (2) is needed, the heating layer heats the device (2) for sterilizing. This simplifies the procedure for sterilizing the device (2).
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