-
1.发明公开AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS 审中-公开AMINOPYRIDINHALTIGE脾酪氨酸激酶（SYK）抑制剂
公开(公告)号：EP2916836A4
公开(公告)日：2016-08-03
申请号：EP13852548
申请日：2013-11-04
申请人： MERCK SHARP & DOHME
IPC分类号： A61K31/44 , A61K9/00 , A61K9/08 , A61K9/20 , A61K9/48 , A61K31/444 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/24 , A61K47/26 , A61K47/38 , C07D417/14
CPC分类号： C07D417/14 , A61K9/0019 , A61K9/008 , A61K9/08 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/4858 , A61K31/444 , A61K45/06 , A61K47/10 , A61K47/186 , A61K47/24 , A61K47/26 , A61K47/38 , A61K2300/00
-
2.发明公开THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS 审中-公开THIAZOLSUBSTITUIERTE AMINOHETEROARYLE ALS MILZTYROSINKINASEHEMMER
公开(公告)号：EP3083560A4
公开(公告)日：2017-07-19
申请号：EP14872688
申请日：2014-12-18
申请人： MERCK SHARP & DOHME
发明人： MILLER THOMAS A , PETROCCHI ALESSIA , ROMEO ERIC T , VITHARANA DILRUKSHI , KATTAR SOLOMON D , NORTHRUP ALAN B , ALTMAN MICHAEL D , ANTHONY NEVILLE J
IPC分类号： C07D417/12 , A61K31/437 , A61K31/4375 , A61K31/444 , A61K31/517 , A61K31/519 , A61P29/00 , A61P37/00 , C07D471/04 , C07D491/048 , C07D495/04
CPC分类号： C07D417/12 , A61K31/437 , A61K31/444 , A61K31/517 , A61K31/519 , C07D413/12 , C07D417/14 , C07D471/04 , C07D491/048 , C07D495/04
-
3.发明公开THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS 审中-公开噻唑取代的氨基水杨酸作为米氮芥诱导酶抑制剂
公开(公告)号：EP2988744A4
公开(公告)日：2016-11-02
申请号：EP14788026
申请日：2014-04-22
发明人： ANTHONY NEVILLE J , ANDRESEN BRIAN M , NORTHRUP ALAN B , CHILDERS KALEEN K , DONOFRIO ANTHONY , MILLER THOMAS A , LIU YUAN , MACHACEK MICHELLE R , WOO HYUN CHONG , SPENCER KERRIE B , ELLIS JOHN MICHAEL , ALTMAN MICHAEL D , ROMEO ERIC T , GUAY DANIEL , GRIMM JONATHAN , LEBRUN MARIE-EVE , ROBICHAUD JOEL S , WANG LIPING , DUBOIS BYRON , DENG QIAOLIN
IPC分类号： A61K31/44 , A61K31/426 , A61K31/53 , A61P11/00 , A61P19/00 , C07D417/12 , C07D417/14
CPC分类号： C07D417/14 , A61K31/4439 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/53 , C07D417/12
摘要： The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
-
公开(公告)号：EP2629777A4
公开(公告)日：2015-01-28
申请号：EP11834913
申请日：2011-10-17
申请人： MERCK SHARP & DOHME
发明人： GUERIN DAVID JOSEPH , BRUBAKER JASON D , MARTINEZ MICHELLE , JUNG JOON O , ANTHONY NEVILLE J , SCOTT MARK E , HOFFMAN DAWN MARIE MAMPREIAN , WOO HYUN CHONG , DINSMORE CHRISTOPHER J
IPC分类号： A61K31/519
CPC分类号： C07D471/04 , A61K31/519 , C07D519/00
摘要： The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
-
公开(公告)号：EP2470012A4
公开(公告)日：2013-01-09
申请号：EP10812548
申请日：2010-08-24
申请人： MERCK SHARP & DOHME
发明人： EDMONDSON SCOTT D , CHANG LEHUA , KAR NAM FUNG , MORRIELLO GREGORI J , MOYES CHRISTOPHER J , SHEN DONG-MING , ZHU CHENG , ANTHONY NEVILLE J , JONES PHILIP , SMITH GRAHAM F , SCOTT MARK E , THOMPSON CHRISTOPHER F , JUNG JOON , CAMMARANO CAROLYN , HOFFMAN DAWN MARIE
IPC分类号： A01N43/38
CPC分类号： C07D401/12 , C07D207/08 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04
-
-
-
-
搜索结果
5 条记录 (耗时 0.01 秒)
