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公开(公告)号：EP3810178A2
公开(公告)日：2021-04-28
申请号：EP19830695.3
申请日：2019-06-20
发明人： RICARDO, Alonso , TUCKER, Thomas, Joseph , BOYER, Nicolas, Cedric , DHAMNASKAR, Ketki, Ashok , MA, Zhong , KEREKES, Angela, Dawn , WU, Chengwei , HA, Sookhee, Nicole , YOUM, Hyewon , BIANCHI, Elisabetta , BRANCA, Danila , INGENITO, Raffaele , COSTANTINI, Willy , SHAHRIPOUR, Aurash , XIONG, Yusheng
IPC分类号： A61K38/12 , A61K38/10 , A61K31/175 , C07K7/50 , A61P3/06
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公开(公告)号：EP3810196A1
公开(公告)日：2021-04-28
申请号：EP19822052.7
申请日：2019-06-20
发明人： RICARDO, Alonso , TUCKER, Thomas, Joseph , BOYER, Nicolas, Cedric , STRINGER, Joseph, R. , LAPLACA, Derek, M. , KEREKES, Angela, Dawn , WU, Chengwei , HA, Sookhee, Nicole , YOUM, Hyewon , EMBREY, Mark, W. , BIANCHI, Elisabetta , BRANCA, Danila , INGENITO, Raffaele , COSTANTINI, Willy , SANTOPRETE, Alessia , COSTANTE, Roberto , CONTE, Immacolata , COLARUSSO, Stefania , GILBERT, Eric, J. , SHAHRIPOUR, Aurash , XIONG, Yusheng
IPC分类号： A61K39/395 , A61P3/06 , A61P9/10 , C07K16/40
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公开(公告)号：EP3934675A2
公开(公告)日：2022-01-12
申请号：EP20716632.3
申请日：2020-03-06
IPC分类号： A61K38/12 , A61K31/506 , A61P7/00 , A61K38/13 , C07K16/28 , A61K39/395
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公开(公告)号：EP3870221A1
公开(公告)日：2021-09-01
申请号：EP19809662.0
申请日：2019-10-22
发明人： DUDA, Petra , FARZANEH-FAR, Ramin , MA, Zhong , ZHU, Nanqun , THACKABERRY, Evan , RICARDO, Alonso
IPC分类号： A61K39/395 , A61K31/506 , A61P7/00 , C07K16/18
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公开(公告)号：EP3551210A1
公开(公告)日：2019-10-16
申请号：EP17829067.2
申请日：2017-12-07
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公开(公告)号：EP3389692A1
公开(公告)日：2018-10-24
申请号：EP16823378.1
申请日：2016-12-07
发明人： DEMARCO, Steven James , HOARTY, Michelle Denise , PARKER, Grace Victoria , RICARDO, Alonso , TOBE, Sylvia , TRECO, Douglas A.
摘要： The present invention relates to polypeptide modulators of complement activity, including cyclic polypeptide modulators. Included are methods of utilizing such modulators as therapeutics.
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公开(公告)号：EP4028126A1
公开(公告)日：2022-07-20
申请号：EP20781171.2
申请日：2020-09-11
发明人： READ, Simon J. , RICARDO, Alonso , SAYEGH, Camil , XU, Xiangyang , TANG, Yalan , TANG, Guo-Qing
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公开(公告)号：EP3947352A1
公开(公告)日：2022-02-09
申请号：EP20721008.9
申请日：2020-03-27
发明人： YOUNGSAYE, Willmen Wing-Menn , GENG, Bolin , HALE, Michael R. , GALULLO, Vincent P. , TIKHE, Jayashree G. , SIEGERT, Timothy Ryan , RICARDO, Alonso , LAPLACA, Derek M. , VADYSIRISACK, Douangsone D. , TANG, Guo-Qing , SEYB, Kathleen , HOARTY, Michelle Denise , BLAIN, Jonathan C. , STRINGER, Joseph R. , GONG, Yongjin , STURINO, Claudio , GALLAGHER-DUVAL, Shawn , DINER, Colin , AKGUN, Burcin , CAO, Qing , TRECO, Douglas A. , RAJAGOPAL, Vaishnavi , DHAMNASKAR, Ketki Ashok , MA, Zhong , ASHWELL, Susan , DAVOREN, Jennifer , LIU, Xiaorong , SAYEGH, Camil , XU, Wenqing , LEMIRE, Alex , BELOUIN, Audrey , JEANNERET, Alexandria , HILDERING, Andrew , BERTANI, Barbara , MICHELI, Fabrizio , PEZZATI, Bernardo , POZZAN, Alfonso
IPC分类号： C07D239/10 , C07D403/10 , C07D413/10 , C07D471/04 , A61P11/00 , A61P13/12 , A61P27/02 , A61K31/4164
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公开(公告)号：EP3389692B1
公开(公告)日：2020-03-04
申请号：EP16823378.1
申请日：2016-12-07
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公开(公告)号：EP2850095A1
公开(公告)日：2015-03-25
申请号：EP13790527.9
申请日：2013-03-14
发明人： WANG, Zhaolin , YE, Ping , RICARDO, Alonso , JOSEPHSON, Kristopher , ANDERSON, Paul , ARATA, Michelle, Denise , MA, Zhong , NIMS, Nathan, Ezekiel , SCHNEIDER, Eberhard , SCHURMANN, Gregor , WAGNER, Peter , TRECO, Douglas, A. , ZHENG, Hong , ELBAUM, Daniel , BOYER, Nicolas, Cedric
IPC分类号： C07K7/54
CPC分类号： A61K38/10 , A61K9/0048 , A61K9/0051 , A61K38/00 , A61K45/06 , A61K47/60 , C07K7/08 , C08G65/48
摘要： The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.
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