摘要:
There is provided a polymer membrane having a surface coating comprising at least one hydroxymethyldiacetoneacrylamide (HMDAA) monomer of formula:
wherein R 1 and R 2 are each independently H or CH 2 OH. There is also provided a method of preparing a coated polymer membrane comprising the steps of: a. providing a porous membrane substrate; b. optionally washing said porous membrane substrate with a wetting liquid to wet the surfaces thereof; c. optionally washing said wet porous membrane substrate with a second wetting liquid to replace said first wetting liquid, leaving said porous membrane substrate wetted with said second liquid; d. contacting the surfaces of said porous membrane substrate with a solution containing: one or more monofunctional monomers, and at least one monomer hydroxymethyldiacetoneacrylamide (HMDAA) monomer of formula:
wherein R 1 and R 2 are each independently H or CH 2 OH; and e. polymerizing said monomers to form said coated membrane.
摘要:
A porous synthetic membrane suitable for conducting macromolecular fluid separations ( e . g ., protein filtration) is described. The ultraporous membrane comprises a surface-charge layer of crosslinked polymer, the crosslinked polymer being formed from a cellulosic polymer and a crosslinking reagent. The cellulosic polymer has substantial crosslinkable hydroxyl moiety content. The crosslinking reagent is a bi- or multi-functional epoxide capable of reacting with and binding to the cellulosic polymer's hydroxyl moieties and has the formula X(CH 2 )nY, wherein: n is an integer from 1 to 5; X is H 2 COCH or H 2 COCHCH 2 O; and Y is a halogen, H 2 COCH, or H 2 COCHCH 2 O. The porous synthetic membrane has good durability and good protein binding characteristics. Surface charge is provided by covalently binding a charged moiety onto a surface of said layer of crosslinked polymer.
摘要:
A porous membrane, such as a microporous or ultrafiltration membrane, is formed from a solution of a polysulfone and a free radical polymerizable monomer exposed to ultraviolet light to form a blend of the polysulfone and copolymers of polysulfone activation products and polymerized monomer having polymer segments covalently bonded to each other. The solution is separated into two phases including a porous solid phase comprising the membrane.
摘要:
The present invention relates to a nanofilter formed by using a porous ultrafiltration membrane as a precursor, and carefully controlling reaction conditions so as to maintain sufficient hydrophilic nature of the membrane while causing the pore structure to close to a nanofilter range (less than 400Daltons), This produces a solvent stable cellulose nanofiltration membrane capable of operating at satisfactory flux in aqueous solutions, and being low binding to organic biomaterials.
摘要:
The present invention relates to a nanofilter formed by using a porous ultrafiltration membrane as a precursor, and carefully controlling reaction conditions so as to maintain sufficient hydrophilic nature of the membrane while causing the pore structure to close to a nanofilter range (less than 400Daltons), This produces a solvent stable cellulose nanofiltration membrane capable of operating at satisfactory flux in aqueous solutions, and being low binding to organic biomaterials.
摘要:
This invention relates to a general method to surface modify porous membranes with a free radical polymerized polymer coating in a layer which is less than the thickness of the membrane. Another object of this invention relates to a general method to surface modify porous membranes with a free radical polymerized polymer coating to a predetermined and controlled depth from a first facial surface. Another object of this invention is to provide a general method to surface modify porous membranes with a free radical polymerized polymer coating into a pattern on one or both facial surfaces, the pattern maintaining its form to a controlled depth into the membrane. Membrane modification is spatially controlled through the use of a polymerization preventing agent (PPA), which prevents modification from occurring in defined spatially volumes of the membrane. The invention relates to porous membranes surface modified by the methods described.