摘要:
The invention relates to a device for the analysis of interactions between biomolecules, comprising a support on which a number of biomolecules are immobilised on the surface of the support material in a regular or irregular arrangement, by means of linkers, whereby two biomolecules are bonded to each linker. The invention further relates to a method for detection of interactions between biopolymers immobilised on a surface, comprising the steps of preparation of a device, according to one of the above claims, setting a defined separation between two biopolymers, immobilised on the surface and the measuring of a signal, generated by the interaction between the two biopolymers.
摘要:
The invention relates to an active ingredient-peptide construct for extracellular enrichment, to a method for enriching active ingredients in an extracellular space of a multicellular object, to the use of the active ingredient-peptide construct according to the invention for producing a pharmaceutical, and to a pharmaceutical composition comprising the active ingredient-peptide construct according to the invention.
摘要:
The present invention relates to novel cyclosporin derivatives that do not cross the cellular membrane. The compounds according to the invention are used in medicine, more particularly in the treatment/diagnosis of acute and chronic inflammatory diseases, viral infections, cancer, degenerative muscle diseases, neurodegenerative diseases and damage that is associated with calcium homeostasis impairment. The novel cyclosporin derivatives additionally have no immunosuppressive effect.