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公开(公告)号：EP2575674A2
公开(公告)日：2013-04-10
申请号：EP11787231.7
申请日：2011-05-24
发明人： SANDHU, Gurpreet, S. , SIMARI, Robert, D. , HOLMES, David, R. , DRAGOMIR DAESCU, M., Dan , PARAKKA, Anthony, P.
CPC分类号： A61F2/82 , A61F2/915 , A61F2230/0054 , A61L31/022 , A61L31/14
摘要： Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The endoprostheses comprise a tubular member capable of maintaining patency of a bodily vessel. The tubular member includes a duplex stainless steel (e.g., 2205 stainless steel), which may be magnetized.
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公开(公告)号：EP2073723A2
公开(公告)日：2009-07-01
申请号：EP07873751.7
申请日：2007-10-10
发明人： SANDHU, Gurpreet, S. , HOLMES, David, R., III , HOLMES, David, R., Jr. , SANDHU, Nicole, P. , SIMARI, Robert, D.
CPC分类号： A61K49/18 , A61B17/22031 , A61B2017/00876 , A61B2017/22035 , A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/0067 , A61F2230/0069 , A61F2230/0071 , A61F2230/0076
摘要： This document provides methods and materials that can be used to reduce or prevent contrast agent-induced toxicity. For example, devices for capturing contrast agents from blood are provided.
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公开(公告)号：EP1699501B1
公开(公告)日：2012-02-08
申请号：EP04812694.0
申请日：2004-12-02
CPC分类号： A61L27/50 , A61F2/06 , A61F2210/009 , A61L27/38 , A61L29/14 , A61L29/16 , A61L2300/606 , A61L2300/64
摘要： Medical devices with surfaces on which viable biologic cells are magnetically attracted and retained are disclosed along with methods of magnetic coating. The medical devices can be located in a carrier liquid containing high concentrations of magnetic cells before or after implantation. The carrier liquid with magnetic cells may be contact with the medical device in vitro or in vivo. In either case, the carrier liquid may have a concentration of magnetic cells that is high enough to facilitate coating of the medical device within an acceptable period of time, e.g., several hours or less. Magnetization of medical devices before, during, and/or after implantation and apparatus for performing the same are disclosed. Degaussing of magnetic medical devices is also disclosed.
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公开(公告)号：EP1638443B1
公开(公告)日：2010-10-20
申请号：EP04754213.9
申请日：2004-06-02
发明人： PAN, Shuchong , SIMARI, Robert, D.
CPC分类号： C07K14/575 , A61K38/00 , C07K14/58 , C07K16/26 , G01N2333/58 , G01N2800/325
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5.发明公开
公开(公告)号：EP2224994A2
公开(公告)日：2010-09-08
申请号：EP08868701.7
申请日：2008-12-19
发明人： SANDHU, Gurpreet, S. , HOLMES, Jr., David, R. , SIMARI, Robert, D. , SANDHU, Nicole, P. , HOLMES III, David, R.
CPC分类号： A61M37/00 , A61K9/5094 , A61N2/002 , A61N2/06
摘要： Systems and methods that provide magnetically-enhanced delivery of therapeutic agents to selected tissue are disclosed. The systems and methods involve the use of carrier devices and release devices and two different magnetic fields to move magnetic particles into selected tissue. Movement of the magnetic particles (and any associated therapeutic agent) into the tissue may be assisted by both magnetic attractive forces as well as magnetic repulsive forces.
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6.发明公开
公开(公告)号：EP1699501A2
公开(公告)日：2006-09-13
申请号：EP04812694.0
申请日：2004-12-02
CPC分类号： A61L27/50 , A61F2/06 , A61F2210/009 , A61L27/38 , A61L29/14 , A61L29/16 , A61L2300/606 , A61L2300/64
摘要： Medical devices with surfaces on which viable biologic cells are magnetically attracted and retained are disclosed along with methods of magnetic coating. The medical devices can be located in a carrier liquid containing high concentrations of magnetic cells before or after implantation. The carrier liquid with magnetic cells may be contact with the medical device in vitro or in vivo. In either case, the carrier liquid may have a concentration of magnetic cells that is high enough to facilitate coating of the medical device within an acceptable period of time, e.g., several hours or less. Magnetization of medical devices before, during, and/or after implantation and apparatus for performing the same are disclosed. Degaussing of magnetic medical devices is also disclosed.
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公开(公告)号：EP1638443A2
公开(公告)日：2006-03-29
申请号：EP04754213.9
申请日：2004-06-02
发明人： PAN, Shuchong , SIMARI, Robert, D.
IPC分类号： A61B1/00
CPC分类号： C07K14/575 , A61K38/00 , C07K14/58 , C07K16/26 , G01N2333/58 , G01N2800/325
摘要： Methods and materials for diagnosing and treating heart conditions (e.g., heart failure) and kidney conditions (e.g., kidney failure) are described.
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