利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

13 条记录 (耗时 0.022 秒)

    MODIFIED RELEASE DOSAGE FORMS
    2.
    发明公开
    MODIFIED RELEASE DOSAGE FORMS 审中-公开
    与改良释放剂型

    公开(公告)号：EP1545452A1

    公开(公告)日：2005-06-29

    申请号：EP03716788.9

    申请日：2003-03-21

    申请人： McNeil-PPC, Inc.

    发明人： LI, Shun-Por ,  LEE, Der-Yang ,  MCNALLY, Gerard, P. ,  MCTEIGUE, Daniel ,  PARIKH, Narendra ,  SOWDEN, Harry, S. ,  WYNN, David

    IPC分类号： A61K9/00

    CPC分类号： A61K9/284 ,  A61K9/0004 ,  A61K9/2072 ,  A61K9/2077 ,  A61K9/2095 ,  A61K9/2893

    摘要： A dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface; and (c) a shell which resides upon at least a portion of the core outer surface, wherein at least a portion of the shell is semipermeable, such that the liquid medium diffuses through the semipermeable shell or shell portion to the core due to osmosis. The shell also provides for delivery of the active ingredient to a liquid medium outside the shell after contacting of the dosage form with the liquid medium. The dosage form delivers one or more active ingredients in a controlled manner upon contacting of the dosage form with a liquid medium. The dosage form may be employed to provide a burst release of the active ingredient, or to provide release of the active ingredient at an ascending release rate over an extended time period upon contacting of the dosage form with a liquid medium.

    SYSTEMS, METHODS AND APPARATUSES FOR MANUFACTURING DOSAGE FORMS
    3.
    发明公开
    SYSTEMS, METHODS AND APPARATUSES FOR MANUFACTURING DOSAGE FORMS 有权
    系统，方法和设备适用剂型生产

    公开(公告)号：EP1429915A1

    公开(公告)日：2004-06-23

    申请号：EP02773600.8

    申请日：2002-09-26

    申请人： McNeil-PPC, Inc.

    发明人： SOWDEN, Harry, S. ,  LI, Shun-Por

    IPC分类号： B30B11/34 ,  A61J3/10

    CPC分类号： A61J3/10 ,  A23G3/04 ,  A23G3/368 ,  A61J3/005 ,  A61K9/2853 ,  A61K9/2873 ,  A61K9/2893 ,  B30B11/08 ,  B30B11/34

    摘要： In one embodiment, a dosage form comprises: (a) at least one active ingredient; (b) a molded core which is solid at room temperature; and (c) a shell which is in contact with at least a portion of the core, wherein the dosage form provides modified release of the active ingredient upon contacting of the dosage form with a liquid medium. In another embodiment of this invention, a dosage form comprises: (a) at least one active ingredient; (b) a molded core comprising a plurality of particles; and (c) a shell which is in contact with at least a portion of the core, wherein the dosage form provides modified release of the active ingredient upon contacting of the dosage form with a liquid medium.

    SYSTEMS, METHODS AND APPARATUSES FOR MANUFACTURING DOSAGE FORMS
    6.
    发明授权
    SYSTEMS, METHODS AND APPARATUSES FOR MANUFACTURING DOSAGE FORMS 有权
    系统，方法和设备适用剂型生产

    公开(公告)号：EP1429915B1

    公开(公告)日：2009-01-14

    申请号：EP02773600.8

    申请日：2002-09-26

    申请人： McNEIL-PPC, Inc.

    发明人： SOWDEN, Harry, S. ,  LI, Shun-Por

    IPC分类号： B30B11/34 ,  A61J3/10

    CPC分类号： A61J3/10 ,  A23G3/04 ,  A23G3/368 ,  A61J3/005 ,  A61K9/2853 ,  A61K9/2873 ,  A61K9/2893 ,  B30B11/08 ,  B30B11/34

    摘要： In one embodiment, a dosage form comprises: (a) at least one active ingredient; (b) a molded core which is solid at room temperature; and (c) a shell which is in contact with at least a portion of the core, wherein the dosage form provides modified release of the active ingredient upon contacting of the dosage form with a liquid medium. In another embodiment of this invention, a dosage form comprises: (a) at least one active ingredient; (b) a molded core comprising a plurality of particles; and (c) a shell which is in contact with at least a portion of the core, wherein the dosage form provides modified release of the active ingredient upon contacting of the dosage form with a liquid medium.

    OSMOTIC TABLET WITH A COMPRESSED OUTER COATING
    10.
    发明公开
    OSMOTIC TABLET WITH A COMPRESSED OUTER COATING 审中-公开
    使用压缩外墙涂料渗透片剂

    公开(公告)号：EP2364143A1

    公开(公告)日：2011-09-14

    申请号：EP09752583.6

    申请日：2009-10-28

    申请人： McNeil-PPC, Inc.

    发明人： CHEN, Vincent ,  LI, Shun-Por ,  SHEN, Robert ,  LEE, Der-Yang

    IPC分类号： A61K9/20 ,  A61K9/00

    CPC分类号： A61K9/209 ,  A61K9/0004

    摘要： The present invention features a method of manufacturing an osmotic tablet including the steps of (i) compressing a tablet core including a first pharmaceutically active agent and a hydrophilic polymer; (ii) applying an osmotic coating to the outer surface of the tablet core to form a coated tablet, wherein the osmotic coating includes at least one opening exposing the tablet core; and (iii) compressing an immediate release coating onto the surface of the coated tablet, wherein the release coating includes a second pharmaceutically active agent.