公开(公告)号：EP2155699A1

公开(公告)日：2010-02-24

申请号：EP08769452.7

申请日：2008-05-12

申请人： Merial Limited ,  Aventis Agriculture

发明人： SOLL, Mark, David ,  LE HIR DE FALLOIS, Loic, Patrick ,  HUBER, Scot, Kevin ,  LEE, Hyoung, Ik ,  WILKINSON, Douglas, Edward ,  JACOBS, Robert, Toms

IPC分类号： C07D249/18 ,  C07D231/56 ,  C07C253/04 ,  C07C255/42 ,  A01N43/707 ,  A01N37/34 ,  A61P33/00

CPC分类号： C07D231/56 ,  C07D249/18

摘要： The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I):wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

公开(公告)号：EP2155699B9

公开(公告)日：2016-09-14

申请号：EP08769452.7

申请日：2008-05-12

申请人： Merial, Inc. ,  Aventis Agriculture

发明人： SOLL, Mark, David ,  LE HIR DE FALLOIS, Loic, Patrick ,  HUBER, Scot, Kevin ,  LEE, Hyoung, Ik ,  WILKINSON, Douglas, Edward ,  JACOBS, Robert, Toms

IPC分类号： C07D249/18 ,  C07D231/56 ,  C07C253/04 ,  C07C255/42 ,  A01N43/707 ,  A01N37/34 ,  A61P33/00

CPC分类号： C07D231/56 ,  C07D249/18

公开(公告)号：EP2155699B1

公开(公告)日：2015-07-08

申请号：EP08769452.7

申请日：2008-05-12

申请人： Merial, Inc. ,  Aventis Agriculture

发明人： SOLL, Mark, David ,  LE HIR DE FALLOIS, Loic, Patrick ,  HUBER, Scot, Kevin ,  LEE, Hyoung, Ik ,  WILKINSON, Douglas, Edward ,  JACOBS, Robert, Toms

IPC分类号： C07D249/18 ,  C07D231/56 ,  C07C253/04 ,  C07C255/42 ,  A01N43/707 ,  A01N37/34 ,  A61P33/00

CPC分类号： C07D231/56 ,  C07D249/18

公开(公告)号：EP2035390A2

公开(公告)日：2009-03-18

申请号：EP07796689.3

申请日：2007-07-03

申请人： Aventis Agriculture

发明人： LEE, Hyoung, IK ,  LE HIR DE FALLOIS, Loic, Patrick ,  TIMMONS, Philip, Reid ,  CAWTHORNE, William, Glenn ,  DE LEON, Adalberto, Perez

IPC分类号： C07D231/18

CPC分类号： A01N43/56 ,  A01N25/02 ,  A01N47/02 ,  A61K31/415 ,  A61K31/4439 ,  A61K45/06 ,  C07D231/18 ,  C07D401/04

摘要： Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R 1 is hydrogen, cyano, halogen, R 8 , formyl, -C(O)R 8 , -C(O)OR 8 , -C(O)NR 9 R 10 , or -C(S)NH 2 ; R 2 is R 8 or -S(O) m R 11 ; R 3 is methyl, ethyl or C 1 -C 4 haloalkyl; R 4 , R 5 and R 7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R 6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, -C(O)R 12 , -S(O) n R 12 or SF 5 ; Z is a nitrogen atom or C-R 13 ; R 3 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R 9 is hydrogen, alkyl, haloalkyl or alkoxy; R 10 is hydrogen, alkyl, haloalkyl or alkoxy; R n is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R 12 is alkyl or haloalkyl; R 13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.

公开(公告)号：EP2364147A2

公开(公告)日：2011-09-14

申请号：EP09760661.0

申请日：2009-11-13

申请人： Merial Limited

发明人： SOLL, Mark, David ,  CRAMER, Luiz, Gustavo ,  WURTZ, Patrice ,  PATE, James ,  SHUB, Natalya ,  LE HIR DE FALLOIS, Loic, Patrick ,  TIMMONS, Philip, Reid

IPC分类号： A61K31/155 ,  A61K31/415 ,  A61K31/4155 ,  A61P33/00 ,  A61P33/14

CPC分类号： A01N43/36 ,  A01N43/56 ,  A01N47/02 ,  A61D7/00 ,  A61K9/0017 ,  A61K31/155 ,  A61K31/231 ,  A61K31/4439 ,  A61K47/08 ,  A61K47/14 ,  A01N25/02 ,  A01N37/52 ,  A01N2300/00 ,  A61K2300/00 ,  A61K31/415

摘要： This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.