公开(公告)号：EP2480166B1

公开(公告)日：2017-11-29

申请号：EP10819570.2

申请日：2010-09-24

申请人： Microvention, Inc.

发明人： CONSTANT, Michael, J. ,  CRUISE, Gregory, M. ,  KEELEY, E., Michael ,  BERENSTEIN, Alejandro

IPC分类号： A61L31/06 ,  A61L31/14 ,  A61L31/18

CPC分类号： A61L31/18 ,  A61L31/06 ,  A61L31/145 ,  A61L31/16 ,  A61L2400/06 ,  C08L71/02

摘要： Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or malformation. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.

公开(公告)号：EP2480166A1

公开(公告)日：2012-08-01

申请号：EP10819570.2

申请日：2010-09-24

申请人： Microvention, Inc.

发明人： CONSTANT, Michael, J. ,  CRUISE, Gregory, M. ,  KEELEY, E., Michael ,  BERENSTEIN, Alejandro

IPC分类号： A61F2/02

CPC分类号： A61L31/18 ,  A61L31/06 ,  A61L31/145 ,  A61L31/16 ,  A61L2400/06 ,  C08L71/02

摘要： Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or malformation. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.

公开(公告)号：EP2231215B1

公开(公告)日：2019-01-30

申请号：EP08867736.4

申请日：2008-12-19

申请人： MicroVention, Inc.

发明人： CRUISE, Gregory, M. ,  CONSTANT, Michael, J. ,  KEELEY, E., Michael ,  TERRANCE, Tran, T.

IPC分类号： A61L27/16 ,  A61L27/18 ,  A61B17/00 ,  A61B17/12 ,  A61B90/00

公开(公告)号：EP2231215A2

公开(公告)日：2010-09-29

申请号：EP08867736.4

申请日：2008-12-19

申请人： MicroVention, Inc.

发明人： CRUISE, Gregory, M. ,  CONSTANT, Michael, J. ,  KEELEY, E., Michael ,  TERRANCE, Tran, T.

IPC分类号： A61L31/04 ,  A61L31/14 ,  A61L31/18

CPC分类号： A61B17/12113 ,  A61B17/12181 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/1205 ,  A61B2090/3966 ,  A61K49/0404 ,  A61L24/001 ,  A61L24/0031 ,  A61L24/046 ,  A61L27/16 ,  A61L27/18 ,  A61L27/56 ,  A61L31/048 ,  A61L31/06 ,  A61L31/146 ,  A61L31/18 ,  A61L2430/36 ,  C08L39/06 ,  C08L71/02

摘要： Described herein are methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or malformation. Further described is a method for forming a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members.

摘要翻译： 这里描述的是用不透射线的水凝胶细丝堵塞结构和畸形的方法，其具有延迟的受控扩张速率，允许将装置重新定位在结构或畸形内。 进一步描述了一种形成用于植入动物的装置的方法，包括双功能低分子量烯属不饱和可成形大分子单体; 烯属不饱和单体; 和不透射线的元件，其中所述装置不包含支撑构件。