-
公开(公告)号:EP0989113B1
公开(公告)日:2004-11-10
申请号:EP98929817.9
申请日:1998-07-03
发明人: HIRASE, Susumu, Taito Co., Ltd , SASAKI, Shigeo, Taito Co., Ltd , YONETA, Masahiko, Taito Co., Ltd , HIROSE, Ryoji, Taito Co., Ltd , FUJITA, Tetsuro
IPC分类号: C07C229/34 , C07C227/16 , C07C215/28 , C07C213/08 , C07C49/80 , C07C49/82 , C07C317/24 , B01J23/44
CPC分类号: C07C309/73 , C07C45/63 , C07C45/673 , C07C213/08 , C07C227/16 , C07C229/36 , C07C233/47 , Y02P20/55 , C07C49/80 , C07C49/82 , C07C215/28
摘要: A process for producing 2-aminomalonic acid derivatives of general formula (1) (wherein A is linear or branched alkylene having 1 to 10 carbon atoms; R1 is linear or branched alkyl having 2 to 20 carbon atoms; R?2 and R3¿ may be the same or different and each represents lower alkyl or aralkyl; and R4 is a protective group) characterized by reducing compounds of general formula (6) (wherein A, R?1, R2, R3 and R4¿ are each as defined above.
-
2.2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME 失效
标题翻译: 2-氨基丙烷-1,3-二醇化合物,其医药用途及其合成中间体产品提出公开(公告)号:EP1002792B1
公开(公告)日:2004-07-14
申请号:EP98911211.5
申请日:1998-04-03
发明人: ADACHI, Kunitomo Yoshitomi Pharm. Industries, , AOKI, Yoshiyuki Yoshitomi Pharm. Industries, Ltd. , HANANO, Tokushi Yoshitomi Pharm. Industries, Ltd. , TESHIMA, Koji Yoshitomi Pharm. Industries, Ltd., , HOSHINO, Yukio Yoshitomi Pharm. Industries, Ltd. , FUJITA, Tetsuro
IPC分类号: C07C225/16 , C07C215/34 , C07C223/02 , A61K31/135
CPC分类号: C07C225/16 , C07C215/34 , C07C223/02 , C07F7/1852
-
3.PRODUCTION OF 2-AMINO-2- 2-(4-C 2-20?-ALKYL-PHENYL)ETHYL]PROPANE-1,3-DIOLS 有权
标题翻译: 制备2-氨基-2-(2-(4-烷基苯基)乙基)丙烷-1,3-二醇公开(公告)号:EP1129066B1
公开(公告)日:2005-02-02
申请号:EP99971797.8
申请日:1999-11-09
IPC分类号: C07C215/28 , C07C213/08 , C07C22/04
CPC分类号: C07C233/47 , C07C17/16 , C07C17/208 , C07C17/35 , C07C22/04 , C07C29/00 , C07C45/46 , C07C45/63 , C07C213/00 , C07C215/28 , C07C49/80 , C07C49/76 , C07C215/08 , C07C33/20
摘要: Disclosed is a process for the production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols.
-
-