公开(公告)号：EP3409766A1

公开(公告)日：2018-12-05

申请号：EP18175639.6

申请日：2018-06-01

申请人： N-Zyme BioTec GmbH ,  Technische Universität Darmstadt

发明人： SARAFEDDINOV, Alla ,  ZOTZEL, Jens ,  MARX, Stefan ,  WARZECHA, Heribert ,  VOLK, Jascha

IPC分类号： C12N9/16 ,  C12N9/18 ,  C12N9/42 ,  C12N15/52 ,  C12N15/82 ,  A23L33/105

CPC分类号： C12N9/16 ,  A23L33/105 ,  C12N9/18 ,  C12N9/2445 ,  C12N15/52 ,  C12N15/8243

摘要： The present invention relates to a polypeptide having esterase activity selected from the group consisting of (a) a polypeptide comprising the amino acid sequence of SEQ ID NO: 7; (b) a polypeptide that is at least 60 % identical to the amino acid sequence of SEQ ID NO: 7 and which is characterized by having an esterase activity; (c) a polypeptide encoded by a nucleic acid molecule which is at least 60 % identical to the nucleic acid sequence of SEQ ID NO: 5 or 6 wherein said polypeptide is characterized by having an esterase activity; (d) a polypeptide encoded by the nucleic acid molecule of SEQ ID NO: 5 or 6; and (e) a polypeptide encoded by the complementary sequence of a nucleic acid molecule that is able to hybridize with the nucleic acid molecule of SEQ ID NO: 5 or 6. Further, the present invention relates to a polypeptide having esterase activity selected from the group consisting of SEQ ID NO: 24 and 37 (as encoded by nuleic acid molecule of SEQ ID NO: 22 or 23 and SEQ ID NO: 35 and 36). The present invention also relates to a method for the production of oleacein, oleocanthal, or decarboxymethyl elenolic acid dialdehyde (DEDA) comprising the use of the esterase of the present invention. to an organism, preferably a plant cell, genetically engineered with a nucleic acid molecule encoding a polypeptide characterized by having an esterase activity or the vector of the present invention. The present invention also relates to a method for the production of oleacein, oleocanthal, and/or decarboxymethyl elenolic acid dialdehyde (DEDA) comprising the use of the esterase of the present invention.

公开(公告)号：EP2215274B1

公开(公告)日：2011-04-13

申请号：EP08852678.5

申请日：2008-11-21

申请人： N-Zyme BioTec GmbH

发明人： ZOTZEL, Jens ,  SARAFEDDINOV, Alla ,  MARX, Stefan ,  GERMANN, Heinz-Peter

IPC分类号： C14C3/12

CPC分类号： C14C3/12 ,  C14C3/08 ,  C14C3/10

摘要： A method for tanning skins and pelts, characterized in that skins and pelts are treated with tanning agents containing deglycosylated iridoids and/or deglycosylated secoiridoids, except for tanning agents which contain genipin.

公开(公告)号：EP3337339A1

公开(公告)日：2018-06-27

申请号：EP16757004.3

申请日：2016-08-19

申请人： N-Zyme BioTec GmbH

发明人： SARAFEDDINOV, Alla ,  ZOTZEL, Jens ,  MARX, Stefan ,  TRETZEL, Joachim

IPC分类号： A23L2/52 ,  B01D11/00 ,  A61K36/63 ,  A23L33/105

摘要： Olive leaf extract containing the following secoiridoid derivatives I) 3,4-DHPEA-EDA and 4-HPEA-EDA, II) 3,4-DHPEA-EA and 4-HPEA-EA, the weight ratio of I) : II) being in the range of 0.5 : 1 to 50 : 1.

公开(公告)号：EP2215274A1

公开(公告)日：2010-08-11

申请号：EP08852678.5

申请日：2008-11-21

申请人： N-Zyme BioTec GmbH

发明人： ZOTZEL, Jens ,  SARAFEDDINOV, Alla ,  MARX, Stefan ,  GERMANN, Heinz-Peter

IPC分类号： C14C3/12

CPC分类号： C14C3/12 ,  C14C3/08 ,  C14C3/10

摘要： A method for tanning skins and pelts, characterized in that skins and pelts are treated with tanning agents containing deglycosylated iridoids and/or deglycosylated secoiridoids, except for tanning agents which contain genipin.