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公开(公告)号：EP3514165A1
公开(公告)日：2019-07-24
申请号：EP17850965.9
申请日：2017-09-14
发明人： MINAGAWA Hirotaka , HORII Katsunori , AKITOMI Jou , KANEKO Naoto , WAGA Iwao , KUWAHARA Masayasu
IPC分类号： C07H19/20 , C07K16/00 , C12N9/26 , C12N15/115
摘要： The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1):
where in the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L 1 and L 2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X 1 and X 2 are each independently an imino group (-NR 1 -), an ether group (-O-), or a thioether group (-S-), and the R 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.-
公开(公告)号：EP3546471A1
公开(公告)日：2019-10-02
申请号：EP17874515.4
申请日：2017-10-12
发明人： MINAGAWA Hirotaka , HORII Katsunori , AKITOMI Jou , KANEKO Naoto , WAGA Iwao , KUWAHARA Masayasu
IPC分类号： C07H19/073 , C12N15/09
摘要： The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1).
In the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L 1 and L 2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X 1 is an imino group (-NR 1 -), an ether group (-O-), or a thioether group (-S-), and R 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.-
公开(公告)号：EP3514164A1
公开(公告)日：2019-07-24
申请号：EP17850964.2
申请日：2017-09-14
发明人： MINAGAWA Hirotaka , HORII Katsunori , AKITOMI Jou , KANEKO Naoto , WAGA Iwao , KUWAHARA Masayasu
IPC分类号： C07H19/073 , C07H19/10 , C07K16/00 , C12N9/26 , C12N15/115
摘要： The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule.
The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1):
where in the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L 1 and L 2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X 1 and X 2 are each independently an imino group (-NR 1 -), an ether group (-O-), or a thioether group (-S-), and the R 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.-
公开(公告)号：EP3514164B1
公开(公告)日：2020-09-09
申请号：EP17850964.2
申请日：2017-09-14
发明人： MINAGAWA Hirotaka , HORII Katsunori , AKITOMI Jou , KANEKO Naoto , WAGA Iwao , KUWAHARA Masayasu
IPC分类号： C07H19/073 , C07H19/10 , C07H21/00 , C12N9/10 , C12N15/115
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