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1.发明授权COMPOSITION CONTAINING ORGANIC SUBSTANCE HAVING DOUBLE BOND WITH IMPROVED OXIDATION STABILITY 有权含有具有改善的氧化稳定性的双键的有机物质的组合物
公开(公告)号：EP1564278B1
公开(公告)日：2018-01-10
申请号：EP03774122.0
申请日：2003-11-21
IPC分类号： C09K15/06 , C11B5/00 , A61K31/202 , A61K31/232 , A61P37/08 , A61K31/341 , A23D9/00
CPC分类号： A23D9/013 , A23D9/00 , A23D9/007 , A23K20/158 , A61K8/345 , A61K8/361 , A61K8/375 , A61K8/4973 , A61K8/498 , A61K8/67 , A61K8/676 , A61K8/922 , A61K8/97 , A61K31/202 , A61K31/232 , A61K31/341 , A61K2800/522 , A61Q19/00 , C09K15/34 , C11B5/0028
摘要： To an organic substance having a double bond such as a polyunsaturated fatty acid was added an antioxidative component containing an antioxidative sesame component and ascorbic acid or an ascorbyl fatty acid ester. The above method provides a composition containing an organic substance having a double bond exhibiting enhanced oxidative stability. Particularly, it extremely improves oxidative stability of fat and oil which contains polyunsaturated fatty acid. General-purpose refined fish oil which is easy to handle can be provided for food, medicine or feed uses.
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公开(公告)号：EP3900543A1
公开(公告)日：2021-10-27
申请号：EP21170839.1
申请日：2014-12-04
IPC分类号： A23D9/013 , A23D9/02 , A23K20/158 , A23L33/115 , A61K8/9706 , A61K8/9728 , A61K31/202 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P29/00 , A61P37/06 , A61P37/08
摘要： A microbial oil comprises dihomo-γ-linolenic acid in fatty acid alkyl ester form and/or in free fatty acid form at a content of at least 50% by weight of the total weight of fatty acids in the oil. The content of thermally-produced fatty acid having from 16 to 22 carbon atoms, generated by heat associated with distillation in the production method, is from 0.0001% by weight to 3.0% by weight of the total weight of fatty acids in the microbial oil. A production method thereof comprises providing a starting oil containing dihomo-γ-linolenic acid in alkyl ester form and/or a free fatty acid form, obtained from microbial biomass; performing rectification of the starting oil under specific conditions; and obtaining the aforementioned microbial oil. Other aspects are a concentrated microbial oil, and use of the described oils as an agent for treating or preventing inflammatory disease.
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3.发明公开
公开(公告)号：EP3848465A1
公开(公告)日：2021-07-14
申请号：EP19857204.2
申请日：2019-09-04
IPC分类号： C12P7/64
摘要： The present invention provides a method of producing a composition containing docosahexaenoic acid as a constituent fatty acid of glycerides, comprising hydrolyzing a feedstock oil containing glycerides comprising docosahexaenoic acid as a constituent fatty acid by action of a Candida cylindracea derived lipase and a partial glyceride lipase, thereby increacing the proportion of docosahexaenoic acid in glyceride fractions, wherein the lipase hydrolysis reaction is performed at a temperature no higher than 30°C for a period no longer than 15 hours.
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公开(公告)号：EP3971165A1
公开(公告)日：2022-03-23
申请号：EP21206640.1
申请日：2013-05-14
IPC分类号： C07C69/587 , A61K31/20 , A61K31/202 , A61K31/232 , A61K35/12 , A61K35/56 , A61K35/60 , A61K35/66 , A61P3/02 , C07C67/54 , C07C67/56
摘要： A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg-TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.
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5.发明授权METHOD OF PRODUCING OIL/FAT COMPRISING HIGHLY-UNSATURATED FATTY ACIDS BY MEANS OF LIPASE 有权工艺用于生产油/油脂与高度不饱和脂肪酸脂肪酶
公开(公告)号：EP2682453B1
公开(公告)日：2017-06-21
申请号：EP12752142.5
申请日：2012-03-02
CPC分类号： C11B3/003 , A23D9/007 , A23D9/04 , C11B1/025 , C11B3/001 , C11B3/12 , C11C1/002 , C11C1/10 , C11C3/00 , C11C3/08 , C12P7/6472
摘要： PROBLEM To provide an oil containing a highly unsaturated fatty acid that has a lower content of cholesterol. MEANS FOR SOLVING A method for producing a highly unsaturated fatty acid-containing glyceride is characterized in that the method comprises the steps of: in a method to concentrate a highly unsaturated fatty acid removing the free form of the sterol from a raw material oil that includes highly unsaturated fatty acid-containing glycerides prior to performing a lipase reaction; and thereafter concentrating the highly unsaturated fatty acid in the highly unsaturated fatty acid-containing glycerides by using a lipase of low reactivity with respect to the highly unsaturated fatty acid. In the produced highly unsaturated fatty acid-containing glycerides, content of the sterol is 0.3 weight% or less, and content of the highly unsaturated fatty acid is 40 area% or more.
摘要翻译： 问题是提供对含油高度不饱和脂肪酸具有确实的胆固醇含量较低。 用于解决一种制造高度不饱和脂肪酸含有酸的甘油酯中DASS模法，其特征在于方法包括以下步骤：在一个方法来浓缩高度不饱和脂肪酸由原料油没有包括去除甾醇的游离形式 高度不饱和脂肪酸以进行脂肪酶反应之前甘油酯含酸; 后，使用低反应性的脂肪酶相对于所述高度不饱和脂肪酸浓缩在高度不饱和脂肪酸的含酸甘油酯的高度不饱和脂肪酸。 在所产生的高度不饱和脂肪酸的含酸甘油酯，甾醇的含量为0.3重量％或更少，并且高度不饱和脂肪酸的含量为40面积％以上。
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6.发明公开METHOD FOR PRODUCTION OF CONDENSED POLYUNSATURATED FATTY ACID OIL 有权VERFAHREN ZUR HERSTELLUNG VON KONZENTRIERTEM MEHRFACHUNGESÄTTIGTEMFETTSÄUREÖL
公开(公告)号：EP2006389A2
公开(公告)日：2008-12-24
申请号：EP07741570.1
申请日：2007-04-13
CPC分类号： C11C3/003 , C07K14/195 , C07K14/21 , C11C3/00 , C11C3/04 , C12P7/64 , C12P7/6427 , C12P7/6436 , C12P7/6445 , C12P7/6454 , C12P7/6472
摘要： The present invention provides a process for concentrated PUFA oil, characterized in that alcoholysis reaction using lipase is carried out in the presence of a small amount of water and at least one compound as an additive selected from magnesium oxide, magnesium hydroxide, calcium oxide and calcium hydroxide, and then separation is conducted to obtain a glyceride fraction.
摘要翻译： 本发明提供一种浓缩PUFA油的方法，其特征在于使用脂肪酶的醇解反应在少量水和至少一种选自氧化镁，氢氧化镁，氧化钙和钙的添加剂的化合物存在下进行 氢氧化物，然后进行分离以获得甘油酯级分。
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公开(公告)号：EP2172558B1
公开(公告)日：2017-07-19
申请号：EP08791785.2
申请日：2008-07-29
发明人： FURIHATA, Kiyomi , KAWAHARA, Hiroyuki , YAMAGUCHI, Hideaki , IKEMOTO, Hideo , DOISAKI, Nobushige
CPC分类号： C11C1/045 , C11C3/10 , C12P7/6472
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8.发明公开METHOD OF PRODUCING OIL/FAT COMPRISING HIGHLY-UNSATURATED FATTY ACIDS BY MEANS OF LIPASE 有权利用脂肪酶生产包含高度不饱和脂肪酸的油/脂的方法
公开(公告)号：EP2682453A1
公开(公告)日：2014-01-08
申请号：EP12752142.5
申请日：2012-03-02
CPC分类号： C11B3/003 , A23D9/007 , A23D9/04 , C11B1/025 , C11B3/001 , C11B3/12 , C11C1/002 , C11C1/10 , C11C3/00 , C11C3/08 , C12P7/6472
摘要： PROBLEM To provide an oil containing a highly unsaturated fatty acid that has a lower content of cholesterol.
MEANS FOR SOLVING A method for producing a highly unsaturated fatty acid-containing glyceride is characterized in that the method comprises the steps of: in a method to concentrate a highly unsaturated fatty acid removing the free form of the sterol from a raw material oil that includes highly unsaturated fatty acid-containing glycerides prior to performing a lipase reaction; and thereafter concentrating the highly unsaturated fatty acid in the highly unsaturated fatty acid-containing glycerides by using a lipase of low reactivity with respect to the highly unsaturated fatty acid. In the produced highly unsaturated fatty acid-containing glycerides, content of the sterol is 0.3 weight% or less, and content of the highly unsaturated fatty acid is 40 area% or more.摘要翻译： 问题提供含有胆固醇含量较低的高度不饱和脂肪酸的油。 [溶解方法]含高度不饱和脂肪酸的甘油酯的制造方法，其特征在于，在从原料油中浓缩去除游离型甾醇的高度不饱和脂肪酸的方法中， 在进行脂肪酶反应之前含高度不饱和脂肪酸的甘油酯; 然后通过使用对高度不饱和脂肪酸具有低反应性的脂肪酶将高度不饱和脂肪酸浓缩在高度不饱和脂肪酸甘油酯中。 在制造的高度不饱和脂肪酸甘油酯中，甾醇的含量为0.3重量％以下，高度不饱和脂肪酸的含量为40面积％以上。
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9.发明公开METHOD FOR PRODUCTION OF EPA-ENRICHED OIL AND DHA-ENRICHED OIL 有权VERFAHREN ZUR HERSTELLUNG VON MIT EPA ANGEREICHERTEMÖLUND MIT DHA ANGEREICHERTEMÖL
公开(公告)号：EP2172558A1
公开(公告)日：2010-04-07
申请号：EP08791785.2
申请日：2008-07-29
发明人： FURIHATA, Kiyomi , KAWAHARA, Hiroyuki , YAMAGUCHI, Hideaki , IKEMOTO, Hideo , DOISAKI, Nobushige
CPC分类号： C11C1/045 , C11C3/10 , C12P7/6472
摘要： Alcoholysis of oils and fats containing EPA and DHA is performed by a lipase having substrate specificity for fatty acids having 18 carbons or less and in the presence of a reaction additive such as magnesium oxide; then the glyceride fraction is separated; alcoholysis of the glyceride fraction is performed by a lipase having substrate specificity for fatty acids having 20 carbons or less and in the presence of a reaction additive such as magnesium oxide; and EPA-enriched oil and DHA-enriched oil are simultaneously obtained.
摘要翻译： 含有EPA和DHA的油和脂肪的醇解通过对具有18个或更少碳原子的脂肪酸和在诸如氧化镁的反应添加剂存在下具有底物特异性的脂肪酶进行， 然后分离甘油酯级分; 甘油酯级分的醇解通过对具有20个碳以下的脂肪酸和在氧化镁等反应添加剂的存在下具有底物特异性的脂肪酶进行， 同时获得富含EPA的油和富含DHA的油。
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10.发明公开COMPOSITION CONTAINING ORGANIC SUBSTANCE HAVING DOUBLE BOND WITH IMPROVED OXIDATION STABILITY 有权ZUSAMMENSETZUNG MIT有机成分物质DOPPELBINDUNG MIT VERBESSERTEROxyidationsSTABILITûT
公开(公告)号：EP1564278A1
公开(公告)日：2005-08-17
申请号：EP03774122.0
申请日：2003-11-21
IPC分类号： C09K15/06 , C11B5/00 , A61K31/202 , A61K31/232 , A61P37/08 , A61K31/341 , A23D9/00
CPC分类号： A23D9/013 , A23D9/00 , A23D9/007 , A23K20/158 , A61K8/345 , A61K8/361 , A61K8/375 , A61K8/4973 , A61K8/498 , A61K8/67 , A61K8/676 , A61K8/922 , A61K8/97 , A61K31/202 , A61K31/232 , A61K31/341 , A61K2800/522 , A61Q19/00 , C09K15/34 , C11B5/0028
摘要： To an organic substance having a double bond such as a polyunsaturated fatty acid was added an antioxidative component containing an antioxidative sesame component and ascorbic acid or an ascorbyl fatty acid ester.
The above method provides a composition containing an organic substance having a double bond exhibiting enhanced oxidative stability. Particularly, it extremely improves oxidative stability of fat and oil which contains polyunsaturated fatty acid. General-purpose refined fish oil which is easy to handle can be provided for food, medicine or feed uses.摘要翻译： 向具有双键的有机物质如多不饱和脂肪酸中加入含有抗氧化芝麻成分和抗坏血酸或抗坏血酸脂肪酸酯的抗氧化成分。 上述方法提供含有具有增强的氧化稳定性的双键的有机物质的组合物。 特别是极度提高含有多不饱和脂肪酸的脂肪和油的氧化稳定性。 易于处理的通用精制鱼油可用于食品，医药或饲料用途。
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