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公开(公告)号:EP1673387B1
公开(公告)日:2010-09-15
申请号:EP04762905.0
申请日:2004-10-08
申请人: NOVO NORDISK A/S
发明人: PESCHKE, Bernd , SCHIØDT, Christine Bruun , WÖLDIKE, Helle , DÖRWALD, Florencio Zaragoza , WORSAAE, Anne
CPC分类号: A61K38/20 , A61K47/60 , C07C237/20 , C07C237/22 , C07C323/60 , C07K14/54 , C07K14/61
摘要: The invention provides derivatives of IL-21 or variants thereof.
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2.
公开(公告)号:EP1765408A2
公开(公告)日:2007-03-28
申请号:EP05754105.4
申请日:2005-06-21
申请人: NOVO NORDISK A/S
CPC分类号: A61K47/48061 , A61K31/41 , A61K38/27 , A61K47/54 , A61K47/545 , C07D257/04 , C07K1/006 , C07K1/113 , C07K14/61
摘要: Method for increasing (protracting) half-life of LGP analogs in plasma and novel derivatives of such peptides based on covalently linking them to a tetrazole moiety which acts as a carboxylic acid bioisostere.
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公开(公告)号:EP1765408B1
公开(公告)日:2015-12-09
申请号:EP05754105.4
申请日:2005-06-21
申请人: NOVO NORDISK A/S
CPC分类号: A61K47/48061 , A61K31/41 , A61K38/27 , A61K47/54 , A61K47/545 , C07D257/04 , C07K1/006 , C07K1/113 , C07K14/61
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公开(公告)号:EP2118121A1
公开(公告)日:2009-11-18
申请号:EP08717055.1
申请日:2008-02-22
申请人: Novo Nordisk A/S
IPC分类号: C07K1/107
CPC分类号: C12N15/70
摘要: Plasmid comprising a DNA tag encoding a peptide tag of the sequence MX1(X 2X 3) n X 1 represents K or R; X 2 represents M, S or T; X 3 represents K or R; n represents an integer of 1 or larger; and wherein said DNA is operably-linked to a promoter sequence are provided.
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