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公开(公告)号：EP4074836A1
公开(公告)日：2022-10-19
申请号：EP20900105.6
申请日：2020-12-02
发明人： MORITA, Tomotake , SAIKA, Azusa , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a monoacylated MEL. A microorganism of the genus Pseudozyma produces monoacylated MEL-B.
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公开(公告)号：EP3778476A1
公开(公告)日：2021-02-17
申请号：EP19775049.0
申请日：2019-03-29
发明人： TSUJI, Katsumi , YONEDA, Keizo , SOGABE, Atsushi , HIRATSUKA, Atsunori , MUGURUMA, Hitoshi , IWASA, Hisanori , TANAKA, Takeshi , ORIHARA, Kouhei
IPC分类号： C01B32/168 , C01B32/159 , C12M1/40 , C12N11/14 , C12Q1/00 , G01N27/30 , G01N27/327
摘要： Provided is a means for promoting electron transfer between nanocarbon and other substances. An electron transfer accelerator for nanocarbon comprising a compound having an aromatic ring skeleton.
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3.发明授权ACTIVATOR COMPRISING BIOSURFACTANT AS THE ACTIVE INGREDIENT MANNOSYL ERYTHRITOL LIPID 有权与生物表面活性剂为活动MANNOSYLERYTHRITOL脂质活化剂
公开(公告)号：EP2055314B1
公开(公告)日：2013-06-19
申请号：EP07792096.5
申请日：2007-08-07
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公开(公告)号：EP4023763A1
公开(公告)日：2022-07-06
申请号：EP20856771.9
申请日：2020-08-24
发明人： MORITA, Tomotake , SAIKA, Azusa , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a means for efficiently producing a monoacyl MEL. This means comprises culturing a monoacyl-MEL-producing microorganism in the presence of a surfactant.
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5.发明授权
公开(公告)号：EP1964546B1
公开(公告)日：2016-10-26
申请号：EP06833085.1
申请日：2006-11-21
发明人： KITAGAWA, Masaru , SUZUKI, Michiko , YAMAMOTO, Shuhei , SOGABE, Atsushi , KITAMOTO, Dai , IMURA, Tomohiro , FUKUOKA, Tokuma , MORITA, Tomotake
CPC分类号： A61K8/602 , A61Q19/00 , A61Q19/008
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公开(公告)号：EP4001423A1
公开(公告)日：2022-05-25
申请号：EP20841145.4
申请日：2020-07-08
发明人： MORITA, Tomotake , SAIKA, Azusa , KOIKE, Hideaki , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a means for increasing mannosylerythritol lipid (MEL) production efficiency. The present invention is a mannosylerythritol-lipid-producing microorganism transformed with an expression vector having a gene that encodes a lipase under the control of E5Pgap promoter or E5Ptef promoter.
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7.发明公开SKIN CARE COSMETIC AND SKIN AND AGENT FOR PREVENTING SKIN ROUGHNESS CONTAINING BIOSURFACTANTS 有权TENSIDE ENTHALTENDES HAUTPFLEGEMITTEL UND MITTEL ZUR VERHINDERUNG VON RAUHER HAUT
公开(公告)号：EP1964546A1
公开(公告)日：2008-09-03
申请号：EP06833085.1
申请日：2006-11-21
申请人： Toyo Boseki Kabushiki Kaisha , National Institute of Advanced Industrial Science and Technology
发明人： KITAGAWA, Masaru , SUZUKI, Michiko , YAMAMOTO, Shuhei , SOGABE, Atsushi , KITAMOTO, Dai , IMURA, Tomohiro , FUKUOKA, Tokuma , MORITA, Tomotake
CPC分类号： A61K8/602 , A61Q19/00 , A61Q19/008
摘要： The present invention relates to a cosmetic for skin roughness improvement/skin care containing a biosurfactant, particularly MEL-A, MEL-B or MEL-C.
摘要翻译： 本发明涉及含有生物表面活性剂，特别是MEL-A，MEL-B或MEL-C的用于皮肤粗糙度改善/护肤的化妆品。
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8.发明公开ACTIVATOR COMPRISING BIOSURFACTANT AS THE ACTIVE INGREDIENT, MANNOSYL ERYTHRITOL LIPID AND METHOD OF PRODUCING THE SAME 有权AKTIVATOR MIT EINEM BIOTENSID ALS WIRKSTOFF MANNOSYLERYTHRITOL-LIPID
公开(公告)号：EP2055314A1
公开(公告)日：2009-05-06
申请号：EP07792096.5
申请日：2007-08-07
申请人： Toyo Boseki Kabushiki Kaisha , National Institute of Advanced Industrial Science and Technology
发明人： SUZUKI, Michiko , KITAGAWA, Masaru , YAMAMOTO, Shuhei , SOGABE, Atsushi , KITAMOTO, Dai , MORITA, Tomotake , FUKUOKA, Tokuma , IMURA, Tomohiro
IPC分类号： A61K45/00 , A23L1/30 , A61K8/92 , A61K31/7032 , A61P3/00 , A61P17/14 , A61P43/00 , A61Q7/00 , A61Q19/08 , C07H15/04 , C07H15/06 , C12P19/12
CPC分类号： C07H15/04 , A23L33/10 , A61K8/60 , A61K31/7032 , A61K36/06 , A61Q19/08 , C07H15/06 , C11D1/662
摘要： The present invention includes as an active ingredient at least one biosurfactant, in particular mannosyl alditol lipid (such as MEL and MML) or triacylated mannosyl alditol lipid. This allows providing an activator and anti-aging agent that is excellent in activating and anti-aging effects on cells and that is safe enough to be used for a long time, and also providing cosmetics, quasi-drugs, drugs, and drinks and foods including the activator and the anti-aging agent as active ingredients. Further, the present invention provides MEL whose mannosyl erythritol skeleton in a molecular structure is 1-O-β-D-mannopyranosyl-meso-erythritol and a method for producing the MEL with use of a microorganism.
摘要翻译： 本发明包括作为活性成分的至少一种生物表面活性剂，特别是甘露糖基糖醇脂质（如MEL和MML）或三酰化甘露糖基糖醇脂质。 这可以提供对细胞的活化和抗衰老作用优异的活化剂和抗老化剂，并且长时间安全使用，还提供化妆品，准药物，药物，饮料和食品 包括活化剂和抗老化剂作为活性成分。 此外，本发明提供了分子结构中的甘露糖基赤藓糖醇骨架为1-O-2-D-吡喃甘露糖基 - 内消旋赤藓糖醇的MEL及使用微生物制备MEL的方法。
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