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1.发明公开SKIN CARE COSMETIC AND SKIN AND AGENT FOR PREVENTING SKIN ROUGHNESS CONTAINING BIOSURFACTANTS 有权TENSIDE ENTHALTENDES HAUTPFLEGEMITTEL UND MITTEL ZUR VERHINDERUNG VON RAUHER HAUT
公开(公告)号：EP1964546A1
公开(公告)日：2008-09-03
申请号：EP06833085.1
申请日：2006-11-21
申请人： Toyo Boseki Kabushiki Kaisha , National Institute of Advanced Industrial Science and Technology
发明人： KITAGAWA, Masaru , SUZUKI, Michiko , YAMAMOTO, Shuhei , SOGABE, Atsushi , KITAMOTO, Dai , IMURA, Tomohiro , FUKUOKA, Tokuma , MORITA, Tomotake
CPC分类号： A61K8/602 , A61Q19/00 , A61Q19/008
摘要： The present invention relates to a cosmetic for skin roughness improvement/skin care containing a biosurfactant, particularly MEL-A, MEL-B or MEL-C.
摘要翻译： 本发明涉及含有生物表面活性剂，特别是MEL-A，MEL-B或MEL-C的用于皮肤粗糙度改善/护肤的化妆品。
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2.发明公开ACTIVATOR COMPRISING BIOSURFACTANT AS THE ACTIVE INGREDIENT, MANNOSYL ERYTHRITOL LIPID AND METHOD OF PRODUCING THE SAME 有权AKTIVATOR MIT EINEM BIOTENSID ALS WIRKSTOFF MANNOSYLERYTHRITOL-LIPID
公开(公告)号：EP2055314A1
公开(公告)日：2009-05-06
申请号：EP07792096.5
申请日：2007-08-07
申请人： Toyo Boseki Kabushiki Kaisha , National Institute of Advanced Industrial Science and Technology
发明人： SUZUKI, Michiko , KITAGAWA, Masaru , YAMAMOTO, Shuhei , SOGABE, Atsushi , KITAMOTO, Dai , MORITA, Tomotake , FUKUOKA, Tokuma , IMURA, Tomohiro
IPC分类号： A61K45/00 , A23L1/30 , A61K8/92 , A61K31/7032 , A61P3/00 , A61P17/14 , A61P43/00 , A61Q7/00 , A61Q19/08 , C07H15/04 , C07H15/06 , C12P19/12
CPC分类号： C07H15/04 , A23L33/10 , A61K8/60 , A61K31/7032 , A61K36/06 , A61Q19/08 , C07H15/06 , C11D1/662
摘要： The present invention includes as an active ingredient at least one biosurfactant, in particular mannosyl alditol lipid (such as MEL and MML) or triacylated mannosyl alditol lipid. This allows providing an activator and anti-aging agent that is excellent in activating and anti-aging effects on cells and that is safe enough to be used for a long time, and also providing cosmetics, quasi-drugs, drugs, and drinks and foods including the activator and the anti-aging agent as active ingredients. Further, the present invention provides MEL whose mannosyl erythritol skeleton in a molecular structure is 1-O-β-D-mannopyranosyl-meso-erythritol and a method for producing the MEL with use of a microorganism.
摘要翻译： 本发明包括作为活性成分的至少一种生物表面活性剂，特别是甘露糖基糖醇脂质（如MEL和MML）或三酰化甘露糖基糖醇脂质。 这可以提供对细胞的活化和抗衰老作用优异的活化剂和抗老化剂，并且长时间安全使用，还提供化妆品，准药物，药物，饮料和食品 包括活化剂和抗老化剂作为活性成分。 此外，本发明提供了分子结构中的甘露糖基赤藓糖醇骨架为1-O-2-D-吡喃甘露糖基 - 内消旋赤藓糖醇的MEL及使用微生物制备MEL的方法。
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公开(公告)号：EP4089178A1
公开(公告)日：2022-11-16
申请号：EP20912348.8
申请日：2020-08-06
发明人： KOSHIYAMA, Tatsuyuki , KANEKO, Mutsumi , HIGASHIYAMA, Yukihiro , SATO, Shun , MORITA, Tomotake , SAIKA, Azusa
摘要： A microorganism of the present invention is Dirkmeia churashimaensis (NITE BP-03054), Papiliotrema flavescens (NITE BP-03051), Papiliotrema flavescens (NITE BP-03052), or Apiotrichum porosum (NITE BP-03053).
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公开(公告)号：EP4074836A1
公开(公告)日：2022-10-19
申请号：EP20900105.6
申请日：2020-12-02
发明人： MORITA, Tomotake , SAIKA, Azusa , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a monoacylated MEL. A microorganism of the genus Pseudozyma produces monoacylated MEL-B.
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5.发明授权ACTIVATOR COMPRISING BIOSURFACTANT AS THE ACTIVE INGREDIENT MANNOSYL ERYTHRITOL LIPID 有权与生物表面活性剂为活动MANNOSYLERYTHRITOL脂质活化剂
公开(公告)号：EP2055314B1
公开(公告)日：2013-06-19
申请号：EP07792096.5
申请日：2007-08-07
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公开(公告)号：EP4317448A1
公开(公告)日：2024-02-07
申请号：EP22777578.0
申请日：2022-03-18
申请人： Allied Carbon Solutions Co., Ltd. , National Institute Of Advanced Industrial Science and Technology
发明人： FUKUOKA, Tokuma , MORITA, Tomotake , KOBAYASHI, Yosuke , HIROTA, Makoto , YASHIRO, Makoto , HIRAYAMA, Shuji , SHIBA, Shunji , YAMAGATA, Yosuke
IPC分类号： C12P19/12 , A23K20/158 , A23K20/163 , A23L2/52 , A23L29/10 , A23L33/125 , A23L33/145 , A61K8/60 , A61K47/26 , A61Q19/10 , C05G3/50 , C07H15/04 , C07H15/08 , C09K23/52 , C11D1/06 , C11D1/68 , C11D3/22
摘要： There is provided a novel sophorolipid derivative having high water solubility and surface activity. A plurality of sophorolipid derivatives having a novel structure is isolated and purified from a cultured product of sophorolipid producing microorganism
( Starmerella bombicola, etc.)
(wherein, R 1 to R 3 are each independently hydrogen, a fatty acid ester having 2 to 22 carbon atoms, or the above SL group, provided that at least one of R 1 to R 3 is the SL group in which R are the same or different and each represent hydrogen or an acetyl group and R n is a linear or branched alkyl or alkenyl group having 13 to 21 carbon atoms).-
公开(公告)号：EP4001423A1
公开(公告)日：2022-05-25
申请号：EP20841145.4
申请日：2020-07-08
发明人： MORITA, Tomotake , SAIKA, Azusa , KOIKE, Hideaki , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a means for increasing mannosylerythritol lipid (MEL) production efficiency. The present invention is a mannosylerythritol-lipid-producing microorganism transformed with an expression vector having a gene that encodes a lipase under the control of E5Pgap promoter or E5Ptef promoter.
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8.发明公开
公开(公告)号：EP4461804A1
公开(公告)日：2024-11-13
申请号：EP22918711.7
申请日：2022-10-31
发明人： KOSHIYAMA, Tatsuyuki , HIGASHIYAMA, Yukihiro , SATO, Shun , MORITA, Tomotake , SAIKA, Azusa , USHIMARU, Kazunori
摘要： The present disclosure relates to a microorganism (NITE BP-03572) belonging to Rhodosporidiobolus azoricus or to a microorganism (NITE BP-03573) belonging to the genus Vanrija.
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公开(公告)号：EP4023763A1
公开(公告)日：2022-07-06
申请号：EP20856771.9
申请日：2020-08-24
发明人： MORITA, Tomotake , SAIKA, Azusa , FUKUOKA, Tokuma , KITAMOTO, Dai , SUGAHARA, Tomohiro , YAMAMOTO, Shuhei , SOGABE, Atsushi
摘要： Provided is a means for efficiently producing a monoacyl MEL. This means comprises culturing a monoacyl-MEL-producing microorganism in the presence of a surfactant.
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公开(公告)号：EP3666893A8
公开(公告)日：2020-08-19
申请号：EP18844470.7
申请日：2018-08-09
发明人： AKITA, Hironaga , NAKAMICHI, Yuusuke , WATANABE, Masahiro , MATSUSHIKA, Akinori , MORITA, Tomotake
摘要： An enzyme having the following characteristics of (a) and (b):
(a) the enzyme has an activity of reversible dehydrogenation of D-amino acid; and
(b) the enzyme is a hexamer of polypeptides having an amino acid sequence that has 80% or more identity with an amino acid sequence of SEQ ID NO: 2.
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