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公开(公告)号：EP3098300A1
公开(公告)日：2016-11-30
申请号：EP15740159.7
申请日：2015-01-23
发明人： HAYASHI, Hisato , OTANI, Misayo , SARUHASHI, Koichiro , NISHINO, Taito , IWAMA, Takehisa , KANAKI, Tatsuro , AIHARA, Ayako
摘要： The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solusion and uniformly dispersed in the liquid medium, and the like.
摘要翻译： 本发明通过使用具有抑制细胞和/或组织沉淀的作用的培养基组合来提供细胞和/或组织的培养方法，所述细胞和/或组织包括培养细胞和/或组织处于悬浮状态，所述培养组合物通过基本上保持细胞 和/或组织，而基本上不增加已经加入到溶液中并均匀分散在液体介质中的纳米纤维的溶液的粘度等。
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公开(公告)号：EP3214209A1
公开(公告)日：2017-09-06
申请号：EP15855309.9
申请日：2015-10-30
发明人： UMEZAKI, Makiko , KISHIOKA, Takahiro , NISHINO, Taito , AIHARA, Ayako , IWAMOTO, Shunsuke , SAKUMA, Daisuke
摘要： An object of the present invention is to provide a ligand-bonded fiber wherein a ligand having affinity for a cell membrane receptor is immobilized on a fiber precursor, and a cell culture substrate capable of repeating ex vivo amplification of a cell expressing a cell membrane receptor by using the ligand-bonded fiber.
A ligand-bonded fiber containing a ligand having affinity for a cell membrane receptor, and a fiber precursor bonded to the ligand.摘要翻译： 本发明的一个目的是提供一种配体结合型纤维，其中对细胞膜受体具有亲和性的配体被固定在纤维前体上，以及能够重复离体扩增表达细胞膜受体的细胞的细胞培养基质 通过使用配体结合纤维。 含有对细胞膜受体具有亲和性的配体的配体结合纤维，以及与配体结合的纤维前体。
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3.发明公开METHOD FOR PRODUCING CULTURE MEDIUM COMPOSITION 审中-公开VERFAHREN ZUR HERSTELLUNG EINER KULTURMEDIUMZUSAMMENSETZUNG
公开(公告)号：EP3098299A1
公开(公告)日：2016-11-30
申请号：EP15740061.5
申请日：2015-01-23
发明人： OTANI, Misayo , SARUHASHI, Koichiro , NISHINO, Taito , AIHARA, Ayako , ISHII, Hisashi , MATSUMOTO, Keigo
CPC分类号： C12N5/0018 , C08B37/006 , C12N5/0025 , C12N2500/34
摘要： The present invention provides a production method of a medium composition, including previously removing divalent metal cations contained in a polymer compound having an anionic functional group, preparing a dry powder of the polymer compound, and mixing the dry powder and the medium, and the like. The present invention also provides a purification method of a polymer compound having an anionic functional group, which includes mixing a suspension of the polymer compound having an anionic functional group in water and a cation exchanger that exchanges a divalent metal cation with a monovalent metal cation to give a polymer compound having an anionic functional group, which shows a reduced amount of contaminating divalent metal cations.
摘要翻译： 本发明提供了一种介质组合物的制备方法，包括预先除去具有阴离子官能团的高分子化合物中所含的二价金属阳离子，制备高分子化合物的干燥粉末，并混合干燥粉末和介质等 。 本发明还提供了具有阴离子官能团的高分子化合物的纯化方法，该方法包括将水中具有阴离子官能团的高分子化合物的悬浮液和将二价金属阳离子与一价金属阳离子交换的阳离子交换剂混合 得到具有阴离子官能团的高分子化合物，其显示出降低量的污染二价金属阳离子。
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公开(公告)号：EP3363870A1
公开(公告)日：2018-08-22
申请号：EP16855532.4
申请日：2016-10-14
IPC分类号： C09D201/06 , A61K35/19 , B01J19/00 , C08F220/34 , C08F230/02 , C09D5/16 , C09D143/02 , C12M1/00 , C12M1/26 , G01N37/00
CPC分类号： C12M23/20 , A61K35/19 , B01J19/00 , C08F220/34 , C08F230/02 , C09D5/16 , C09D143/02 , C09D201/06 , C12M1/00 , C12M1/26 , C12M23/16 , G01N37/00
摘要： This is to provide a coating agent for a flow passage which is capable of being coated on the inner surface of the flow passage with an extremely simple and easy operation and having an excellent ability to inhibit adhesion of a biological substance, and a flow passage device having the coating agent for a flow passage on at least part of an inner surface of a flow passage, a platelet-producing flow passage device and a method for manufacturing the same.
Provided are a coating agent for a flow passage which comprises a copolymer containing a recurring unit which contains an organic group of the following formula (a) and a recurring unit which contains an organic group of the following formula (b), and a flow passage device having the coating agent for a flow passage on at least part of an inner surface of a flow passage, a platelet-producing flow passage device and a method for manufacturing the same.
wherein U a1 , U a2 , U b1 , U b2 , U b3 and An - are as defined in the present specification and the claims.
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