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公开(公告)号：EP1670515A2
公开(公告)日：2006-06-21
申请号：EP04762844.1
申请日：2004-09-17
申请人： NOVO NORDISK A/S
发明人： LAU, Jesper , HANSEN, Thomas Kruse , MADSEN, Kjeld , BLOCH, Paw , DÖRWALD, Florencio Zaragoza , JOHANSEN, Nils Langeland
IPC分类号： A61K47/48
CPC分类号： C07K14/605 , A61K38/00 , A61K38/26 , A61K47/54 , A61K47/542 , A61K47/60 , C07K14/001
摘要： Novel polypeptide derivatives having protracted profile of action
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公开(公告)号：EP2057189A1
公开(公告)日：2009-05-13
申请号：EP07802841.2
申请日：2007-08-24
申请人： NOVO NORDISK A/S
发明人： LAU, Jesper , HANSEN, Thomas Kruse , CHRISTENSEN, Leif , MADSEN, Kjeld , SCHÄFFER, Lauge , SPETZLER, Jane
IPC分类号： C07K14/605 , A61K38/26 , A61P3/08 , A61P5/48
CPC分类号： C07K14/57563 , A61K38/00 , A61K38/26 , A61K47/48038 , A61K47/48046 , A61K47/48061 , A61K47/48215 , A61K47/542 , A61K47/543 , A61K47/545 , A61K47/60 , C07K14/605
摘要： This invention provides new therapeutic peptides, i.e. new protracted Exendin-4 compounds, pharmaceutical compositions and the use of such.
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公开(公告)号：EP1799711A2
公开(公告)日：2007-06-27
申请号：EP05801691.6
申请日：2005-10-07
申请人： NOVO NORDISK A/S
发明人： LAU, Jesper , HANSEN, Thomas Kruse
IPC分类号： C07K14/605 , A61K38/26
CPC分类号： C07K14/57563 , A61K38/00
摘要： Novel protracted exendin-4 compounds and therapeutic uses thereof.
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公开(公告)号：EP1996617A2
公开(公告)日：2008-12-03
申请号：EP07726944.7
申请日：2007-03-15
申请人： NOVO NORDISK A/S
IPC分类号： C07K14/575
CPC分类号： C07K14/4713 , A61K38/00 , C07K14/5759
摘要： The present invention relates to novel amylin derivatives having a protracted action profile, to pharmaceutical compositions comprising these derivatives and to the use of the derivatives for the treatment of diseases related to obesity, diabetes and other metabolic disorders.
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公开(公告)号：EP1863521A1
公开(公告)日：2007-12-12
申请号：EP06725150.4
申请日：2006-03-20
申请人： Novo Nordisk A/S
IPC分类号： A61K38/26 , C07K14/605
CPC分类号： C07K14/605 , A61K38/00
摘要： Protracted GLP-1 compounds and therapeutic uses thereof.
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6.发明公开SYNTHESIS AND APPLICATION OF NEW STRUCTURAL WELL DEFINED BRANCHED POLYMERS AS CONJUGATING AGENTS FOR PEPTIDES 审中-公开合成及结构井的应用程序定义的支化聚合物AS KONJUGATMITTEL肽
公开(公告)号：EP1654004A2
公开(公告)日：2006-05-10
申请号：EP04739028.1
申请日：2004-08-09
申请人： NOVO NORDISK A/S
发明人： BEHRENS, Carsten , DÖRWALD, Florencio Zaragoza , KOFOD-HANSEN, Mikael , LAU, Jesper , KODRA, János Tibor , HANSEN, Thomas Kruse , BLOCH, Paw
IPC分类号： A61K47/48
CPC分类号： A61K38/26 , A61K38/4846 , A61K47/60 , C12Y304/21021
摘要： The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.
摘要翻译： 本发明提供了合成和新的结构良好限定的支化聚合物作为用于肽和蛋白质牵引剂的应用。
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公开(公告)号：EP1704165B1
公开(公告)日：2010-03-17
申请号：EP04803037.3
申请日：2004-12-17
申请人： NOVO NORDISK A/S
IPC分类号： C07K14/605 , C07K14/575 , A61K38/26 , A61K38/22
CPC分类号： C07K14/57563 , A61K38/00 , C07K14/605
摘要： Novel GLP-1 compounds and their therapeutic use.
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公开(公告)号：EP1996224A1
公开(公告)日：2008-12-03
申请号：EP07726938.9
申请日：2007-03-15
申请人： Novo Nordisk A/S
CPC分类号： A61K38/28 , A61K9/0019 , A61K38/22 , A61K2300/00
摘要： The present invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide, and a meal-related insulin peptide, and to the use of such compositions for treatment of e.g. hyperglycemia.
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公开(公告)号：EP1765408A2
公开(公告)日：2007-03-28
申请号：EP05754105.4
申请日：2005-06-21
申请人： NOVO NORDISK A/S
CPC分类号： A61K47/48061 , A61K31/41 , A61K38/27 , A61K47/54 , A61K47/545 , C07D257/04 , C07K1/006 , C07K1/113 , C07K14/61
摘要： Method for increasing (protracting) half-life of LGP analogs in plasma and novel derivatives of such peptides based on covalently linking them to a tetrazole moiety which acts as a carboxylic acid bioisostere.
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公开(公告)号：EP1704165A1
公开(公告)日：2006-09-27
申请号：EP04803037.3
申请日：2004-12-17
申请人： NOVO NORDISK A/S
IPC分类号： C07K14/605 , C07K14/575 , A61K38/26 , A61K38/22
CPC分类号： C07K14/57563 , A61K38/00 , C07K14/605
摘要： Novel GLP-1 compounds and their therapeutic use.
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