GROUP 2 MITE POLYPEPTIDE VARIANTS
    1.
    发明公开
    GROUP 2 MITE POLYPEPTIDE VARIANTS 审中-公开
    第2组小鼠多肽变体

    公开(公告)号:EP1812463A2

    公开(公告)日:2007-08-01

    申请号:EP05796454.6

    申请日:2005-10-21

    申请人: Novozymes A/S

    CPC分类号: C07K14/43531 A61K39/00

    摘要: This invention concerns variants of group 2 mite polypeptides, wherein the polypeptide of the variant comprise one or more mutations in the positions or corresponding to the positions consisting of D64, V40, E53, S57, K82, G83, I97 of SEQ ID NO: 1 or 64, 40, 53, 57, 82, 83, 97 of the Der p 2 polypeptide or the positions G32, D59, L61, E62, A98 of SEQ ID NO: 2 or 32, 59, 61, 62, 98 of the Der f 2 polypeptide.

    摘要翻译: 本发明涉及第2组螨多肽的变体,其中该变体的多肽在由SEQ ID NO:1的D64,V40,E53,S57,K82,G83,I97组成的位置或对应于该位置处包含一个或多个突变 或SEQ ID NO:2的位置G32,D59,L61,E62,A98或32位,59位,62位,62位,98位或64位,40位,53位,57位,82位,83位,97位 Der f 2多肽。

    SIGNAL PEPTIDE FOR PRODUCING A POLYPEPTIDE
    3.
    发明公开
    SIGNAL PEPTIDE FOR PRODUCING A POLYPEPTIDE 有权
    SIGNALPEPTID ZUR HERSTELLUNG EINES POLYPEPTIDS

    公开(公告)号:EP1756273A1

    公开(公告)日:2007-02-28

    申请号:EP05748651.6

    申请日:2005-06-14

    申请人: Novozymes A/S

    IPC分类号: C12N9/18 C12N15/62 C12N15/81

    摘要: The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising said nucleic acid construct.

    摘要翻译: 本发明涉及包含使用信号肽的多肽的制备方法,其包含编码信号肽的第一核苷酸序列和编码第一核苷酸序列异源的多肽的第二核苷酸序列的核酸构建体。 此外,它还涉及包含所述核酸构建体的表达载体和宿主细胞。

    SUBTILASE VARIANTS
    5.
    发明公开
    SUBTILASE VARIANTS 有权
    枯草变异

    公开(公告)号:EP1904628A1

    公开(公告)日:2008-04-02

    申请号:EP06753336.4

    申请日:2006-07-06

    申请人: Novozymes A/S

    IPC分类号: C12N9/54 C11D3/386

    CPC分类号: C11D3/38636 C12N9/54

    摘要: The present invention relates to novel subtilase variants exhibiting improvements relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.

    SUBTILASE VARIANTS
    8.
    发明授权
    SUBTILASE VARIANTS 有权
    反转变形

    公开(公告)号:EP1904628B1

    公开(公告)日:2011-10-19

    申请号:EP06753336.4

    申请日:2006-07-06

    申请人: Novozymes A/S

    IPC分类号: C12N9/54 C11D3/386

    CPC分类号: C11D3/38636 C12N9/54

    摘要: The present invention relates to novel subtilase variants exhibiting improvements relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.

    摘要翻译: 本发明涉及新型枯草杆菌酶变体,其在一种或多种性质中表现出相对于亲本枯草杆菌酶的改善,包括:洗涤性能,热稳定性,储存稳定性或催化活性。 本发明的变体适用于例如 清洁或洗涤剂组合物,例如洗衣洗涤剂组合物和洗碗组合物,包括自动洗碗组合物。

    IMPROVED ALPHA FACTOR SIGNAL PEPTIDE FOR PRODUCING A POLYPEPTIDE
    10.
    发明公开
    IMPROVED ALPHA FACTOR SIGNAL PEPTIDE FOR PRODUCING A POLYPEPTIDE 审中-公开
    维生素ALPHA-FAKOR-SIGNALPEPTID ZUR HERSTELLUNG EINES POLYPEPTIDS

    公开(公告)号:EP2074215A2

    公开(公告)日:2009-07-01

    申请号:EP07821708.0

    申请日:2007-10-23

    申请人: Novozymes A/S

    IPC分类号: C12N15/80 C12N15/81 C12N15/62

    摘要: The present invention relates to a method for producing a polypeptide comprising using a variant alpha factor signal peptide having a substitution in position 9 resulting in a substitution of an A to either T, S, H, I, F, E, or G. The invention further relate to nucleic acid constructs comprising a first nucleotide sequence encoding the variant signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising said nuclei acid construct.

    摘要翻译: 本发明涉及一种生产多肽的方法,其包括使用在位置9具有取代的变体α因子信号肽,导致A取代T,S,H,I,F,E或G。 本发明进一步涉及包含编码变体信号肽的第一核苷酸序列和编码第一核苷酸序列异源的多肽的第二核苷酸序列的核酸构建体。 此外,它还涉及包含所述核酸构建体的表达载体和宿主细胞。