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公开(公告)号:EP1963530A4
公开(公告)日:2009-08-05
申请号:EP06848008
申请日:2006-12-21
发明人: HANZEL DAVID , KORLACH JONAS , PELUSO PAUL , OTTO GEOFFREY , PHAM THANG , RANK DAVID , TURNER STEPHEN
CPC分类号: C12Q1/6837 , C07K2319/23 , C12N9/1252 , C12Q1/6844 , C12Q2521/101 , C12Q2565/531
摘要: Active surface coupled polymerases, surfaces that include such polymerases, and methods of making and using surface-attached polymerases are provided.
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公开(公告)号:EP2252625A4
公开(公告)日:2014-07-02
申请号:EP09707425
申请日:2009-02-06
发明人: OTTO GEOFFREY , SHEN GENE , KONG XIANGXU , EMIG ROBIN
摘要: The present invention provides methods and compositions for performing illuminated reactions, particularly sequencing reactions, while mitigating and/or preventing photodamage to reactants that can result from prolonged illumination. In particular, the invention provides methods and compositions for incorporating photoprotective agents into conjugates comprising reporter molecules and nucleoside polyphosphates.
摘要翻译: 本发明提供用于进行照明反应,特别是测序反应的方法和组合物,同时减轻和/或防止可能由长时间照射引起的对反应物的光损伤。 特别地,本发明提供了将光保护剂掺入包含报道分子和核苷多磷酸的缀合物中的方法和组合物。
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公开(公告)号:EP2027253A4
公开(公告)日:2014-04-30
申请号:EP07845184
申请日:2007-06-11
IPC分类号: C12M3/00
CPC分类号: G02B6/10 , G01N21/648 , G01N2021/7713
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公开(公告)号:EP1971364A4
公开(公告)日:2010-06-30
申请号:EP06838800
申请日:2006-12-01
发明人: EID JOHN , MURPHY DEVON , OTTO GEOFFREY , TURNER STEPHEN
CPC分类号: A61K38/446 , A61K38/063 , A61K38/443 , G01N33/582
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