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公开(公告)号：EP1478322A4
公开(公告)日：2007-08-08
申请号：EP02756310
申请日：2002-06-24
发明人： CHU CHUNG K , OTTO MICHAEL J , SHI JUNXING , SCHINAZI RAYMOND F , CHOI YONGSEOK , GUMINA GIUSEPPE , CHONG YOUHOON , STUYVER LIEVEN J
IPC分类号： A01N43/04 , A61K31/52 , A61K31/522 , A61K31/675 , A61K31/70 , A61K31/7064 , A61K31/7068 , A61K31/7076 , A61K45/00 , A61P31/14 , A61P31/18 , A61P35/00 , C07H9/04 , C07H19/06 , C07H19/16
CPC分类号： A61K31/70 , A61K31/52 , A61K31/522 , A61K31/675 , C07H9/04 , C07H19/06
摘要： The present invention includes compounds and compositions of β-halonucleosides, as well as methods to treat HIV, HBV or abnormal cellular proliferation comprising administering said compounds or compositions.
摘要翻译： 本发明包括β-卤代核苷的化合物和组合物，以及治疗HIV，HBV或异常细胞增殖的方法，包括施用所述化合物或组合物。
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2.发明公开TREATMENT OF EBV AND KHSV INFECTION AND ASSOCIATED ABNORMAL CELLULAR PROLIFERATION 审中-公开EB病毒和KHSV感染治疗和相关的细胞增殖异常
公开(公告)号：EP1569658A4
公开(公告)日：2007-05-30
申请号：EP02795977
申请日：2002-12-19
IPC分类号： C07D239/54 , A61K31/513 , A61K31/58 , A61K31/7072 , A61K38/16 , A61K45/06 , A61K48/00 , A61P31/12 , A61P35/00 , A61P43/00 , C07D405/04 , C07D405/14 , C07D409/14 , C07H19/067 , C07H19/073 , C07J43/00
CPC分类号： C07H19/06 , A61K31/513 , A61K31/7072 , A61K45/06 , C07D239/54 , C07D405/04 , C07D409/04 , A61K2300/00
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公开(公告)号：EP2155771A4
公开(公告)日：2012-09-05
申请号：EP08767681
申请日：2008-05-14
申请人： RFS PHARMA LLC , UNIV EMORY , UNIV PITTSBURGH
发明人： SCHINAZI RAYMOND F , MELLORS JOHN W , SLUIS-CREMER NICOLAS PAUL , AMBLARD FRANK , COAST STEVEN J , SHI JUNXING , WHITAKER RICHARD ANTHONY
IPC分类号： C07H19/173 , A61K31/7076 , A61P31/12 , C07D473/16 , C07D473/18 , C07D473/34
CPC分类号： C07H19/173 , C07D473/16 , C07D473/18 , C07D473/34
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4.发明公开POTENT AND SELECTIVE INHIBITORS OF HEPATITIS C VIRUS 审中-公开POTENTE ANDD SELEKETIVE INHIBITOREN DES HEPATITIS-C-VIRUS
公开(公告)号：EP3131892A4
公开(公告)日：2017-09-20
申请号：EP15779578
申请日：2015-04-15
申请人： COCRYSTAL PHARMA INC , UNIV EMORY
发明人： COATS STEVEN J , WHITAKER RICHARD ANTHONY , MCBRAYER TAMARA ROSARIO , SHI JUNXING , AMBLARD FRANCK , ZHANG HONGWANG , ZHOU LONGHU , SCHINAZI RAYMOND F
IPC分类号： C07D403/14 , A61K31/4178 , A61P31/14
CPC分类号： C07D401/14 , A61K31/4178 , A61K45/06 , C07D403/14
摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.
摘要翻译： 本发明涉及用于治疗或预防人受试者或其他动物宿主中丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 这些化合物也是药学上可接受的，盐，前药和其它衍生物，作为用于治疗或预防HCV感染的药物组合物和方法。
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公开(公告)号：EP2616461A4
公开(公告)日：2014-03-26
申请号：EP11820753
申请日：2011-08-26
申请人： RFS PHARMA LLC , UNIV EMORY
发明人： COATS STEVEN J , AMBLARD FRANCK , ZHANG HONGWANG , ZHOU LONGHU , WHITAKER RICHARD ANTHONY , MCBRAYER TAMARA ROSARIO , SCHINAZI RAYMOND F , SHI JUNXING
IPC分类号： C07D403/04 , A61K31/4178 , A61P31/14 , C07D403/14 , C07D405/14 , C07D413/14
CPC分类号： C07D403/14 , A61K31/4178 , A61K31/4192 , A61K31/444 , A61K31/506 , A61K31/5377 , A61K31/655 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D407/14 , C07D413/14
摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.
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