摘要:
Devices for the depletion of leukocytes in blood products, preferably comprising an upstream porous element including means for removal of gels, at least one intermediate porous element including means for removal of microaggregates, and a downstream element including means for removal of leukocytes by both adsorption and filtration, preferably with at least one of the elements having been modified to a CWST in excess of 53 dynes/cm.
摘要:
A corrugated tubular filter element (1) is provided, resistant to corrugation collapse under high differential pressure, although formed of filter sheet material susceptible to such collapse, comprising, in combination, filter sheet material (2) enclosed in a dual layer of more open foraminous sheet material and formed in a closed corrugated configuration having axial corrugation folds arranged in groups (4) with adjacent side surfaces in supporting contact with each other; and, interposed between said groups, solid wedge support elements (10) extending axially of the corrugation folds from end to end of the element having side surfaces in supporting contact with external side surfaces of the end folds of each group, substantially filling the spaces between the end folds of adjacent groups, and confining the folds of each group in substantially parallel array against lateral movement; and a foraminous support sheath (15,16) disposed at least one of externally and internally of the filter sheet material in supporting contact with adjacent fold ends and retaining the wedge support elements and folds against one of outward and inward movement.
摘要:
Devices for the depletion of leukocytes in blood products, preferably comprising an upstream porous element including means for removal of gels, at least one intermediate porous element including means for removal of microaggregates, and a downstream element including means for removal of leukocytes by both adsorption and filtration, preferably with at least one of the elements having been modified to a CWST in excess of 53 dynes/cm.
摘要:
A system for collecting and processing donated blood comprises a first porous medium interposed between a blood collection bag and a satellite bag and a second porous medium interposed between the blood collection bag and another satellite bag. The porous media are leucocyte depletion media. The system may also include one or more of the following: a red cell barrier medium, a separation medium, a gas inlet, and a gas outlet. The system can be used to centrifuge whole blood into one or more components, and includes a means for protecting the system during centrifugation. To this end, the porous medium is contained in a rigid plastic housing forming a filter assembly (114). This filter assembly (114) is cooperatively arranged with a centrifuge bucket (120) such that the filter assembly is located away from the greatest amount of G force.
摘要:
A filter cartridge is provided comprising, in combination: (1) a filter sheet material formed in a tube open at at least one end; (2) a support such as an internal core or external sheath disposed in supporting relation to and substantially coextensive with the tube and supporting the filter sheet material of the tube; (3) the support having one end at the open end of the tube formed in a castellated configuration in which at least some of the castellations define grooves therebetween, preferably having reentrant sides; and (4) at least one end cap attached to and extending across the open end of the tube of filter sheet material, and having embedded therein at least the castellated end of the support, with end cap material extending into and substantially filling the grooves, thereby fixedly attaching the end cap to the support in a leak-tight seal.