-
公开(公告)号：EP4276099A1
公开(公告)日：2023-11-15
申请号：EP22736595.4
申请日：2022-01-07
发明人： CHEN, Kevin X , XIONG, Jian , WANG, Jingjing , HU, Guoping , LIU, Jinxin , HAN, Yu , LI, Jian , CHEN, Shuhui
IPC分类号： C07D421/14 , C07D471/14 , C07D519/00 , C07D513/14 , C07D498/14 , C07F11/00 , A61K31/503 , A61K31/53 , A61P31/16
摘要： Provided are a class of pyridone multiple-membered ring derivatives and the use thereof. Specifically provided are a compound as represented by formula (VI) and a pharmaceutically acceptable salt thereof.
-
公开(公告)号：EP3988553A1
公开(公告)日：2022-04-27
申请号：EP20827468.8
申请日：2020-06-19
发明人： CHEN, Kevin X , ZHANG, Li , ZHOU, Kai , YU, Yanxin , HU, Boyu , ZHANG, Huiyu
IPC分类号： C07D498/04 , A61K31/517 , A61P35/00 , C07D403/12 , C07D405/14
摘要： The present invention relates to a crystal form and a salt of a compound serving as a Pan-HER tyrosine kinase inhibitor and a preparation method therefor, and also use thereof in the preparation of a medicament for treating solid tumors.
-
公开(公告)号：EP3498715A1
公开(公告)日：2019-06-19
申请号：EP17838686.8
申请日：2017-08-08
发明人： XIONG, Jian , WANG, Jingjing , WU, Wentao , TAN, Haizhong , PENG, Xuanjia , ZHANG, Yang , CHEN, Kevin X , LI, Jian , CHEN, Shuhui
IPC分类号： C07D495/04 , A61K31/519 , A61P31/22
摘要： Disclosed are a class of fused cyclic compounds against the HCMV virus, and use thereof in the preparation of a drugs for treating diseases associated with the HCMV virus. In particular, disclosed is the compound shown in formula (II) and pharmaceutically acceptable salts thereof.
-
公开(公告)号：EP3992189A1
公开(公告)日：2022-05-04
申请号：EP20831428.6
申请日：2020-06-24
发明人： CHEN, Kevin X , CHEN, Zhaoguo , ZHANG, Li , HU, Boyu , CHEN, Shuhui
IPC分类号： C07D403/10 , C07D487/00 , A61K31/495 , A61K31/47 , A61P35/00
摘要： Disclosed in the present invention are a compound as represented by formula (I), and an isomer or pharmaceutically acceptable salt thereof, and disclosed is an application thereof in preparing drugs for treating DNA-PK inhibitor-related diseases.
-
5.发明公开
公开(公告)号：EP3766884A1
公开(公告)日：2021-01-20
申请号：EP19793622.2
申请日：2019-04-28
发明人： CHEN, Kevin X , YU, Yanxin , CHEN, Xinde , ZHANG, Li , CHEN, Zhaoguo , XIE, Cheng
IPC分类号： C07D487/04 , A61K31/505 , A61K31/519 , A61P25/16 , A61P35/00
摘要： Disclosed in the present invention are a crystal form of a [1,2,4]triazol[1,5-c]pyrimidine compound and a preparation method therefor. Further disclosed is a use of the crystal form in the preparation of a medicine for treating A 2A receptor related diseases. (I)
-
公开(公告)号：EP4067359A1
公开(公告)日：2022-10-05
申请号：EP20892868.9
申请日：2020-11-25
发明人： CHEN, Kevin X , XIA, Shanghua , CHEN, Zhaoguo , GUO, Zuhao , YU, Yanxin , ZHOU, Kai , HU, Boyu , ZHANG, Li , JIANG, Fen , WANG, Jingjing , HU, Guoping , LI, Jian , CHEN, Shuhui
IPC分类号： C07D473/18 , C07D519/00 , A61K31/522 , A61P35/00
摘要： A class of DNA-PK inhibitors, in particular a compound represented by formula (IV) or a pharmaceutically acceptable salt thereof, and an application thereof in the preparation of a drug relating to a DNA-PK inhibitor.
-
公开(公告)号：EP3611174A1
公开(公告)日：2020-02-19
申请号：EP18781739.0
申请日：2018-04-08
发明人： CHEN, Kevin X , YU, Yanxin , CHEN, Xinde , ZHANG, Li , CHEN, Zhaoguo , XIE, Cheng , WANG, Xiaofei , WU, Linghui , HU, Guoping , LI, Jian , CHEN, Shuhui
IPC分类号： C07D487/04 , A61K31/505 , A61K31/519 , A61P25/16 , A61P43/00
摘要： Provided are a compound represented by formula (I), an isomer or a pharmaceutically acceptable salt thereof, and an application of the same in preparing a drug for treating a disease related to A 2A receptor. The R 1 , R 2 , R 3 , ring A, ring B, n, and m are as defined in the specification.
-
公开(公告)号：EP4219461A1
公开(公告)日：2023-08-02
申请号：EP21871464.0
申请日：2021-09-18
发明人： CHEN, Kevin X , GUO, Zuhao , YU, Yanxin , HU, Boyu , WANG, Jingjing , CHEN, Zhaoguo , XIE, Cheng , XIONG, Jian , FANG, Yongbo , LIU, Yingtao , LI, Jian , CHEN, Shuhui
IPC分类号： C07D401/12 , C07D413/12 , C07D217/04 , A61K31/4725 , A61P35/00
摘要： A series of tetrahydroisoquinoline derivatives and the crystal forms thereof. Specifically disclosed are a compound as represented by formula (VII), a crystal form thereof, and a pharmaceutically acceptable salt thereof.
-
公开(公告)号：EP4129997A1
公开(公告)日：2023-02-08
申请号：EP21781242.9
申请日：2021-04-06
发明人： CHEN, Shuhui , CHEN, Kevin X , ZHOU, Kai , JIANG, Wen , HU, Guoping , LI, Jian
IPC分类号： C07D403/14 , C07D413/14 , C07D498/22 , A61K31/551 , A61K31/553 , A61P35/00
摘要： Disclosed is a class of octahydropyrazinodiazanaphthyridine dione compounds, and specifically disclosed are a compound as shown in formula (III) and a pharmaceutically acceptable salt thereof.
-
10.发明公开
公开(公告)号：EP3967698A1
公开(公告)日：2022-03-16
申请号：EP20802767.2
申请日：2020-05-06
发明人： CHEN, Kevin X , CHEN, Zhaoguo , ZHANG, Li , YU, Yanxin , ZHOU, Kai , JIANG, Fen , XIA, Shanghua , WANG, Xiaofei
IPC分类号： C07D519/00 , C07D471/04 , A61K31/5386 , A61K31/5377 , A61P35/00 , A61P35/02
摘要： Disclosed are a salt and a crystal form of an mTORC1/2 dual kinase inhibitor and a preparation method therefor. Also disclosed is use of the salt and crystal form in the preparation of a medicament related to the mTORC1/2 dual kinase inhibitor. (I)
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.015 秒)
