公开(公告)号：EP2013829A2

公开(公告)日：2009-01-14

申请号：EP07776655.8

申请日：2007-05-02

申请人： Proteus Biomedical, Inc.

发明人： ZDEBLICK, Mark ,  THOMPSON, Andrew ,  SAVAGE, George

IPC分类号： G06Q10/00

CPC分类号： G06F19/3456 ,  A61B5/0002 ,  A61B5/0028 ,  A61B5/073 ,  A61B5/4833 ,  A61B5/4848 ,  G06F19/00 ,  G06F19/34 ,  G06F19/3418 ,  G06F19/345 ,  G06F19/3475 ,  G06Q10/00 ,  G06Q50/22 ,  G16H50/20 ,  H01M8/02 ,  H01M2220/10 ,  H04B13/005 ,  Y10S128/903 ,  Y10S128/92

摘要： Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.

公开(公告)号：EP2358270A2

公开(公告)日：2011-08-24

申请号：EP09832576.4

申请日：2009-12-10

申请人： Proteus Biomedical, Inc.

发明人： SAVAGE, George ,  HAFEZI, Hooman ,  COLLIOU, Olivier ,  ZDEBLICK, Mark ,  STRAND, Angela

IPC分类号： A61B5/05 ,  A61B1/273

CPC分类号： A61B5/053 ,  A61B5/04884 ,  A61B5/073 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/42 ,  A61B5/6861 ,  A61B2560/0214 ,  A61B2560/0242 ,  G06F19/00

摘要： Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

公开(公告)号：EP2276400A2

公开(公告)日：2011-01-26

申请号：EP09747375.5

申请日：2009-05-12

申请人： Proteus Biomedical, Inc.

发明人： ARNE, Lawrence ,  BANOS, Orlando ,  BEHZADI, Yashar ,  COLLIOU, Olivier ,  COSTELLO, Benedict ,  LEICHNER, Robert ,  MOON, Gregory ,  ROBERTSON, Timothy ,  SAVAGE, George ,  THOMPSON, Todd ,  ZDEBLICK, Mark

IPC分类号： A61B5/0402 ,  A61B5/0408

CPC分类号： A61B5/046 ,  A61B5/0006 ,  A61B5/0031 ,  A61B5/0422 ,  A61B5/0536 ,  A61B5/0538 ,  A61B5/4519 ,  A61B5/743 ,  A61B5/7435 ,  A61B6/503 ,  A61B8/0883 ,  G06F19/00

摘要： Continuous field tomography systems are provided. Aspects of systems include a data aggregating module configured to receive both continuous field tomography data and non-continuous field physiological data and produce an aggregated data product from these disparate types of data. Also provided are methods of using systems of the invention in a variety of different applications, including diagnostic and therapeutic applications. The systems and methods of the invention find use in a variety of different applications, such as cardiac related applications.

公开(公告)号：EP2385781A2

公开(公告)日：2011-11-16

申请号：EP10729473.8

申请日：2010-01-06

申请人： Proteus Biomedical, Inc.

发明人： JENSEN, Marc ,  LEICHNER, Robert ,  BEAULIEU, Patrick ,  AU-YEUNG, Kit Yee ,  ARNE, Lawrence ,  ZDEBLICK, Mark ,  THOMPSON, Andrew ,  SAVAGE, George ,  ROBERTSON, Timothy ,  BEHZADI, Yashar

IPC分类号： A61B1/00 ,  A61B5/02 ,  A61B5/0482 ,  H04B13/00

CPC分类号： A61B5/073 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/486 ,  A61B5/6833 ,  G06F19/00 ,  G06F19/3456 ,  G06F19/3481 ,  G16H10/60 ,  G16H20/00 ,  G16H20/10 ,  H04B13/005

摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

公开(公告)号：EP2350969A2

公开(公告)日：2011-08-03

申请号：EP09821214.5

申请日：2009-10-14

申请人： Proteus Biomedical, Inc.

发明人： THOMPSON, Andrew ,  SAVAGE, George ,  KARPLUS, Erika ,  ARNE, Lawrence ,  ROBERTSON, Timothy ,  O'REILLY, David

IPC分类号： G06Q50/00

CPC分类号： A63F13/23 ,  A61B5/02055 ,  A61B5/02405 ,  A61B5/073 ,  A61B5/0816 ,  A61B5/4833 ,  A63F13/02 ,  A63F13/212 ,  A63F2300/1012 ,  A63F2300/6045 ,  G06F19/00 ,  G06Q50/00 ,  G07F17/32 ,  G07F17/3206 ,  G07F17/3237

摘要： The present invention provides a receiving device and method for use with gaming pursuits, including, in one aspect, a personal signal receiver to communicate physiologic data, a hub to receive the physiologic data, and a gaming module to receive, directly or indirectly, the physiologic data from the hub.

公开(公告)号：EP2346391A2

公开(公告)日：2011-07-27

申请号：EP09828058.9

申请日：2009-11-13

申请人： Proteus Biomedical, Inc.

发明人： STRAND, Angela ,  ZDEBLICK, Mark ,  SAVAGE, George ,  O' REILLY, David

IPC分类号： A61B5/00 ,  A61B5/02 ,  G05F1/00

CPC分类号： A61N1/36071 ,  A61N1/05 ,  A61N1/36132 ,  A61N1/36135 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481

摘要： Sensing system, device, and method for therapy modulation are provided. Various aspects include a receive module and a therapy-related action module. The receive module may receive a therapy parameter of an individual. The therapy-related action module may effectuate, based on the therapy parameter, a therapy-related action associated with a nervous system of the individual.

公开(公告)号：EP2313002A2

公开(公告)日：2011-04-27

申请号：EP09795007.5

申请日：2009-07-02

申请人： Proteus Biomedical, Inc.

发明人： O'REILLY, David ,  KARPLUS, Erika ,  THOMPSON, Andrew ,  SAVAGE, George ,  ZDEBLICK, Mark ,  ROBERTSON, Timothy ,  ARNE, Lawrence ,  BEHZADI, Yashar ,  MOON, Gregory ,  BEAULIEU, Patrick

IPC分类号： A61B5/06 ,  H04B13/00 ,  G05F1/00

CPC分类号： A61B5/07 ,  A61B5/0022 ,  A61B5/021 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3456

摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

公开(公告)号：EP2107883A2

公开(公告)日：2009-10-14

申请号：EP08728864.3

申请日：2008-02-01

申请人： Proteus Biomedical, Inc.

发明人： ROBERTSON, Timothy ,  SAVAGE, George ,  ZDEBLICK, Mark ,  BEHZADI, Yashar ,  COSTELLO, Benedict ,  FRANK, Jeremy ,  HAFEZI, Hooman ,  HANIFF, Tariq ,  O'REILLY, David

IPC分类号： A61B1/05

CPC分类号： A61B5/073 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/0073 ,  A61B5/0205 ,  A61B5/14507 ,  A61B5/6846 ,  A61B5/6861 ,  A61B5/6873 ,  A61B2560/0214 ,  A61J3/007 ,  G01N27/3277 ,  H01M6/005 ,  H01Q1/273 ,  H04B5/0068 ,  Y10S128/903

摘要： Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

公开(公告)号：EP1898999A2

公开(公告)日：2008-03-19

申请号：EP06785999.1

申请日：2006-06-30

申请人： Proteus Biomedical, Inc.

发明人： JENSEN, Marc ,  COLLIOU, Olivier ,  COSTELLO, Benedict ,  ZDEBLICK, Mark ,  THOMPSON, Todd ,  SAVAGE, George ,  THOMPSON, Andrew

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： Minimally invasive deployable epicardial array devices are provided. The devices include deployable platform comprising two or more effectors, such as sensors and actuators, where the devices are configured to be deployed at an epicardial location via a minimally invasive, e.g., sub-xiphoid approach. In embodiments of the present invention, at least one area of the electrode patch is an electrical control area that comprises a series of effectors, e.g., sensors and/or electrodes. Other embodiments provide localized physical constraint and dynamic mechanical stimulation of the heart to effectuate physical and biological responses. Still other embodiments provide both of these functions. Also provided are methods of using the devices, as well as systems and kits that include the devices.

公开(公告)号：EP1871470A2

公开(公告)日：2008-01-02

申请号：EP06749135.7

申请日：2006-03-31

申请人： Proteus Biomedical, Inc.

发明人： ZDEBLICK, Mark ,  SAVAGE, George ,  OMIDVAR, Fataneh ,  COLLIOU, Olivier ,  ARNE, Lawrence ,  COSTELLO, Benedict ,  THOMPSON, Todd

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/08 ,  A61N1/36185 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/3686 ,  A61N1/37247

摘要： One embodiment of the present invention provides a system for automatically optimizing CRT procedures using a multi-electrode pacing lead. During operation, the system performs a first set of iterations to select one or more satellites on one or more pacing leads inserted in a patient. A pacing lead includes a plurality of pacing satellites, and a pacing satellite includes a plurality of electrodes that can be individually addressed and used for transmitting or detecting electric signals. The system then performs a second set of iterations to select one or more electrodes on the selected satellites. The system further performs a third set of iterations to select one or more timing configurations for pacing signals transmitted through one or more of the selected electrodes.