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    PYRAZOLO - TRIAZINE DERIVATIVES AS SELECTIVE CYCLIN- DEPENDENT KINASE INHINITORS
    4.
    发明公开
    PYRAZOLO - TRIAZINE DERIVATIVES AS SELECTIVE CYCLIN- DEPENDENT KINASE INHINITORS 有权
    PYRAZOLOTRIAZINDERIVATE作为选择性细胞周期蛋白依赖性激酶抑制剂

    公开(公告)号：EP2820020A1

    公开(公告)日：2015-01-07

    申请号：EP13707008.2

    申请日：2013-03-01

    申请人： Lead Discovery Center GmbH

    发明人： EICKHOFF, Jan ,  ZISCHINSKY, Gunther ,  KOCH, Uwe

    IPC分类号： C07D487/04 ,  A61K31/53 ,  A61P9/00 ,  A61P29/00 ,  A61P31/00 ,  A61P35/00

    CPC分类号： C07D491/107 ,  C07D471/10 ,  C07D487/04

    摘要： The present invention relates to pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors for a protein kinase.