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    METHOD / DEVICE FOR GENERATING A CORRECTED VALUE OF AN ANALYTE CONCENTRATION IN A SAMPLE OF A BODY FLUID
    2.
    发明公开
    METHOD / DEVICE FOR GENERATING A CORRECTED VALUE OF AN ANALYTE CONCENTRATION IN A SAMPLE OF A BODY FLUID 审中-公开
    方法/ DEVICE用于产生校正后的值的体液样品中的分析物浓度

    公开(公告)号：EP2976643A1

    公开(公告)日：2016-01-27

    申请号：EP14710588.6

    申请日：2014-03-18

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： HOENES, Joachim ,  RINGEMANN, Christian ,  WELLER, Andreas

    IPC分类号： G01N33/543

    CPC分类号： G01N33/5094 ,  G01N21/75 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/525 ,  G01N33/558 ,  G01N33/66

    摘要： A method for detecting an analyte in a body fluid is disclosed. The method has the following steps: a) applying a sample (122) of the body fluid to a test element (120), said test element (120) comprising at least (i) a test field (128) comprising at least one test material (130) adapted to change at least one measurable property in the presence of the analyte, (ii) a capillary element (126) adapted to guide the sample (122) across said test field (128) in a flow direction (146), (iii) a first and a second measurement location (158, 160) within said test field (128), wherein the second measurement location (160) is offset from the first measurement location (158) in the flow direction (146); b) measuring the measurable property in said at least one first measurement location (158), thereby generating at least one first measurement value; c) measuring the measurable property in said at least one second measurement location (160), thereby generating at least one second measurement value; d) detecting the analyte by using an evaluation algorithm having at least two input variables, wherein (i) at least one first input variable of the at least two input variables includes an information on a difference between the first measurement value and the second measurement value, and (ii) at least one second input variable of the at least two input variables includes a measurement information on an analyte-induced change of the measurable property of the test material (130) in at least part of the test field (128).

    METHOD FOR THE EVALUATION OF THE QUALITY OF A TEST ELEMENT
    5.
    发明公开
    METHOD FOR THE EVALUATION OF THE QUALITY OF A TEST ELEMENT 有权
    程序用于评估测试元件的质量

    公开(公告)号：EP2807270A1

    公开(公告)日：2014-12-03

    申请号：EP13701570.7

    申请日：2013-01-23

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： HAAR, Hans-Peter ,  HOENES, Joachim ,  HORN, Carina ,  PETERICH, Wolfgang ,  FREIFRAU VON KETTELER, Alexa

    IPC分类号： C12Q1/54 ,  C12M1/34 ,  G01N33/66

    CPC分类号： C12Q1/54 ,  G01N33/573 ,  G01N33/5735

    摘要： The present invention relates to a method for evaluating the quality of an analysis element which is useful for determining the concentration of an analyte in a liquid sample, and to an analysis system which implements such a method. A reaction of the sample with a reagent system includes a complex formation of at least an enzyme and a co-enzyme, wherein a chemically modified form of the co-enzyme is a fluorophore. The quantity and/or the luminescence properties of said fluorophore relate to the concentration of the analyte. The quality of the analysis element is evaluated using an evaluation algorithm, wherein the evaluation algorithm comprises obtaining information relating to a measured enzyme activity AEnz(measured), wherein said information is at least partly derived from a measurement of the fluorescence lifetime of the fluorophore.

    ANALYSESYSTEM MIT MESSVORRICHTUNG UND TESTELEMENT
    6.
    发明公开
    ANALYSESYSTEM MIT MESSVORRICHTUNG UND TESTELEMENT 审中-公开

    公开(公告)号：EP2693943A1

    公开(公告)日：2014-02-12

    申请号：EP12712966.6

    申请日：2012-04-02

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： EIKMEIER, Heino ,  HAAR, Hans-Peter ,  HOENES, Joachim ,  HORN, Carina ,  RIEGER, Ewald

    IPC分类号： A61B5/1455 ,  A61B5/145 ,  A61B5/1468

    CPC分类号： G01N33/49 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1468 ,  A61B2560/04 ,  A61B2560/0406 ,  A61B2560/0418 ,  A61B2560/0425

    摘要： The invention relates to a portable diagnostic measurement device for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid and particularly preferably for blood glucose determinations, and to an analysis system which comprises the measurement device and at least one disposable (to be used one time) testing element. The testing element, designed as a carrier strip, contacts a receiving surface of the diagnostic measurement device at least partially in a flat manner, wherein the receiving surface is arranged on a narrow side of the housing of the measurement device.

    摘要翻译： 该装置具有容纳在装置的接收表面（20）上的测试元件（41），其中接收表面设置在壳体（1）的窄侧或狭窄侧的一部分上。 壳体的窄边的窄边或部分相对于装置的相邻部件升高和/或设置有暴露层。 壳体部分以30至70度的角度在接收表面上成角度，并且平面垂直于机器平面穿过接收表面或相对于大约20至70度的角度的垂直布置安装。

    TESTELEMENT ZUR ANALYSE EINER KÖRPERFLÜSSIGKEIT
    10.
    发明公开
    TESTELEMENT ZUR ANALYSE EINER KÖRPERFLÜSSIGKEIT 有权
    测试元件FOR A体液分析

    公开(公告)号：EP2464290A1

    公开(公告)日：2012-06-20

    申请号：EP10742091.1

    申请日：2010-08-03

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： HAAR, Hans-Peter ,  HOENES, Joachim

    IPC分类号： A61B5/151 ,  G01N33/52 ,  C12Q1/54 ,  A61B5/00

    CPC分类号： A61B5/14532 ,  A61B2562/0295

    摘要： The invention relates to a test element (3) for producing a puncture wound in a body part, for obtaining a body fluid specimen from the body part and for analyzing, by way of a reagent system, the reaction of which has an analyte present in the body fluid leading to a change of a measured value, said change being characteristic for the desired analytical result and able to be optically measured on the test element (3), which comprises a puncturing element (4) and a test field (5). The puncturing element (4) comprises a capillary structure (13) and a sharp tip (19) at one end of the puncturing element (4) for producing a wound in the body part. The capillary structure (13) extends from the sharp tip (19) to the test field (5), and is fluidly connected to the sharp tip (19) such that after the skin is punctured by the sharp tip (19) of the puncturing element (4), body fluid penetrates the capillary structure (13), and that the test field (5) contains at least part of the reagent system, and that the test field (3) is arranged adjacent to a segment of the capillary structure (13) of the puncturing element (4) such that the body fluid having penetrated the capillary structure (13), makes contact with a fluid inlet side (104) of the test field (5). The test field (5) comprises a transparent base layer (45, 100) and a test layer (101) applied to the base layer (45, 100) by a coating process, wherein the side of the base layer (45, 100) facing away from the test field (5) forms the fluid inlet side (104) thereof, which faces the capillary structure (13).