专利检索 ap:("SCHERING AKTIENGESELLSCHAFT") AND inv:"GARFIELD, Robert, E." 第 1 页

1.

发明公开
TREATMENT OF URINARY INCONTINENCE WITH NITRIC OXIDE SYNTHASE SUBSTRATES AND/OR NITRIC OXIDE DONORS 失效
标题翻译：尿失禁用氮气氧化氮合酶衬底及/或治疗DONORS

公开(公告)号：EP0874627A1

公开(公告)日：1998-11-04

申请号：EP97902990.0

申请日：1997-01-21

申请人： SCHERING AKTIENGESELLSCHAFT , BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM

发明人： GARFIELD, Robert, E. , CHWALISZ, Kristof

IPC分类号： A61K31 , A61P13

CPC分类号： A61K31/566 , A61K31/198 , A61K31/21 , A61K31/295 , A61K31/34 , A61K31/56 , A61K31/565 , A61K31/569 , A61K31/57 , A61K31/575 , A61K2300/00

摘要： The invention provides a method for the treatment and prevention of urinary incontinence in mammals, e.g., human males and females, especially nonpregnant female mammals, by administering a nitric oxide synthase substrate and/or nitric oxide donor, alone or in combination with an estrogenic agent and/or a progestational substance, with or without supplementation with an alpha-adrenergic agonist, beta-adrenergic receptor blocking agent, cholinergic-receptor blocking compound or a cholinergic-receptor-stimulating drug, as well as pharmaceutical compositions useful in practicing the methods of this invention.

2.

发明公开
TREATMENT OF CLIMACTERIC DISORDERS WITH NITRIC OXIDE SYNTHASE SUBSTRATES AND/OR DONORS 失效
标题翻译：用硝酸衬底和/或DONORS更年期症状治疗

公开(公告)号：EP0730445A1

公开(公告)日：1996-09-11

申请号：EP95900760.0

申请日：1994-11-17

申请人： SCHERING AKTIENGESELLSCHAFT , Yallampalli, Chandra , GARFIELD, Robert

发明人： YALLAMPALLI, Chandra , GARFIELD, Robert, E. , CHWALISZ, Kristof , BUKOWSKI, Radoslaw

IPC分类号： A61K31 , A61P9 , A61P13 , A61P15

CPC分类号： A61K31/565 , A61K31/04 , A61K31/195 , A61K31/198 , A61K31/295 , A61K31/341 , A61K31/57 , A61K31/60 , Y10S514/899 , A61K31/41 , A61K31/34 , A61K31/21 , A61K2300/00 , A61K31/557 , A61K31/26

摘要： The symptoms of the climacterium are ameliorated by the administration to an afflicted individual one or both of a nitric oxide substrate and/or nitric acid donor, alone or optionally in combination with a progestin or, in the case of non-pregnant female, either a progestin or an estrogen or both.

3.

发明公开
COMBINATION OF PROSTACYCLIN WITH AN ESTROGEN OR PROGESTIN FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROTIC VASCULAR DISEASE INCLUDING PREECLAMPSIA AND FOR THE TREATMENT OF HYPERTENSION, AND FOR HORMONE REPLACEMENT THERAPY 失效
标题翻译：预防和复方制剂治疗血管疾病动脉硬化，前列环素和雌激素或孕激素CONTAINS

公开(公告)号：EP0790827A2

公开(公告)日：1997-08-27

申请号：EP95935145.0

申请日：1995-09-22

申请人： SCHERING AKTIENGESELLSCHAFT

发明人： GARFIELD, Robert, E. , CHWALISZ, Kristof

IPC分类号： A61K31 , A61P5 , A61P9 , A61P13 , A61P15

CPC分类号： A61K31/566 , A61K31/565 , A61K31/567 , A61K31/57 , A61K31/5585 , A61K2300/00

摘要： Cardiovascular disease, including preeclampsia in pregnant women and hypertension in both women and men, are prevented or treated by administering thereto prostacyclin or a prostacyclin analog in combination with one or both of an estrogen and a progestin, which combination is also useful for HRT in peri- and post-menopausal women.