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公开(公告)号:EP0955961A2
公开(公告)日:1999-11-17
申请号:EP97912864.0
申请日:1997-10-21
申请人: SDGI Holdings, Inc.
发明人: PAFFORD, John , BOYD, Lawrence, M. , MCKAY, William, F. , RAY, Eddie, F., III , VAN HOECK, James, E.
CPC分类号: A61F2/30767 , A61B17/1671 , A61B17/1757 , A61B2017/0256 , A61B2090/034 , A61F2/28 , A61F2/30724 , A61F2/442 , A61F2/4455 , A61F2/446 , A61F2/447 , A61F2/4611 , A61F2/468 , A61F2002/2817 , A61F2002/2835 , A61F2002/2839 , A61F2002/30004 , A61F2002/30057 , A61F2002/30062 , A61F2002/30075 , A61F2002/30112 , A61F2002/30136 , A61F2002/30153 , A61F2002/30187 , A61F2002/30224 , A61F2002/30235 , A61F2002/30261 , A61F2002/30271 , A61F2002/30677 , A61F2002/30772 , A61F2002/30774 , A61F2002/30787 , A61F2002/30797 , A61F2002/30813 , A61F2002/30836 , A61F2002/30841 , A61F2002/30848 , A61F2002/3085 , A61F2002/30866 , A61F2002/30879 , A61F2002/30892 , A61F2002/30904 , A61F2002/3092 , A61F2002/30929 , A61F2002/4475 , A61F2002/448 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628 , A61F2002/4649 , A61F2210/0004 , A61F2210/0061 , A61F2230/0004 , A61F2230/0019 , A61F2230/0034 , A61F2230/0069 , A61F2230/0082 , A61F2250/0014 , A61F2310/00161 , A61F2310/00293 , A61F2310/00365 , A61F2310/00491 , A61F2310/00544 , A61F2310/00796 , A61L27/10 , A61L27/12 , A61L27/16 , A61L27/18 , A61L27/24 , A61L27/54 , A61L31/024 , A61L31/026 , A61L31/044 , A61L31/047 , A61L31/048 , A61L31/06 , A61L2300/252 , A61L2300/414 , A61L2300/802 , A61L2430/38 , Y10S606/907 , Y10S606/908 , Y10S606/909 , Y10S606/91 , A61L27/227
摘要: Spinal spacers (20) are provided for fusion of a motion segment. The spacers include a load bearing member (21) having a wall (22) sized for engagement within a space between adjacent vertebrae to maintain the space and an effective amount of an osteogenic composition (30) to stimulate osteoinduction. The osteogenic composition includes a substantially pure osteogenic factor in a pharmaceutically acceptable carrier. In one embodiment the load bearing member includes a bone graft impregnated in an osteogenic composition. In another embodiment, the osteogenic composition (30) is packed within a chamber (25) defined in the graft. Any suitable configuration of a bone graft is contemplated, including bone dowels, D-shaped spacers and cortical rings.
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公开(公告)号:EP0955961B1
公开(公告)日:2004-03-31
申请号:EP97912864.2
申请日:1997-10-21
申请人: SDGI Holdings, Inc.
发明人: PAFFORD, John , BOYD, Lawrence, M. , MCKAY, William, F. , RAY, Eddie, F., III , VAN HOECK, James, E.
CPC分类号: A61F2/30767 , A61B17/1671 , A61B17/1757 , A61B2017/0256 , A61B2090/034 , A61F2/28 , A61F2/30724 , A61F2/442 , A61F2/4455 , A61F2/446 , A61F2/447 , A61F2/4611 , A61F2/468 , A61F2002/2817 , A61F2002/2835 , A61F2002/2839 , A61F2002/30004 , A61F2002/30057 , A61F2002/30062 , A61F2002/30075 , A61F2002/30112 , A61F2002/30136 , A61F2002/30153 , A61F2002/30187 , A61F2002/30224 , A61F2002/30235 , A61F2002/30261 , A61F2002/30271 , A61F2002/30677 , A61F2002/30772 , A61F2002/30774 , A61F2002/30787 , A61F2002/30797 , A61F2002/30813 , A61F2002/30836 , A61F2002/30841 , A61F2002/30848 , A61F2002/3085 , A61F2002/30866 , A61F2002/30879 , A61F2002/30892 , A61F2002/30904 , A61F2002/3092 , A61F2002/30929 , A61F2002/4475 , A61F2002/448 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628 , A61F2002/4649 , A61F2210/0004 , A61F2210/0061 , A61F2230/0004 , A61F2230/0019 , A61F2230/0034 , A61F2230/0069 , A61F2230/0082 , A61F2250/0014 , A61F2310/00161 , A61F2310/00293 , A61F2310/00365 , A61F2310/00491 , A61F2310/00544 , A61F2310/00796 , A61L27/10 , A61L27/12 , A61L27/16 , A61L27/18 , A61L27/24 , A61L27/54 , A61L31/024 , A61L31/026 , A61L31/044 , A61L31/047 , A61L31/048 , A61L31/06 , A61L2300/252 , A61L2300/414 , A61L2300/802 , A61L2430/38 , Y10S606/907 , Y10S606/908 , Y10S606/909 , Y10S606/91 , A61L27/227
摘要: Spinal spacers (20) are provided for fusion of a motion segment. The spacers include a load bearing member (21) having a wall (22) sized for engagement within a space between adjacent vertebrae to maintain the space and an effective amount of an osteogenic composition (30) to stimulate osteoinduction. The osteogenic composition includes a substantially pure osteogenic factor in a pharmaceutically acceptable carrier. In one embodiment the load bearing member includes a bone graft impregnated in an osteogenic composition. In another embodiment, the osteogenic composition (30) is packed within a chamber (25) defined in the graft. Any suitable configuration of a bone graft is contemplated, including bone dowels, D-shaped spacers and cortical rings.
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