公开(公告)号：EP1185221B1

公开(公告)日：2005-03-23

申请号：EP00938115.3

申请日：2000-06-02

申请人： SDGI Holdings, Inc.

发明人： ZDEBLICK, Thomas, A. ,  MCKAY, William, F.

IPC分类号： A61F2/44

CPC分类号： A61B17/1757 ,  A61B17/86 ,  A61F2/30742 ,  A61F2/30965 ,  A61F2/441 ,  A61F2/442 ,  A61F2/4425 ,  A61F2/4611 ,  A61F2002/30092 ,  A61F2002/30121 ,  A61F2002/30123 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30228 ,  A61F2002/3023 ,  A61F2002/30238 ,  A61F2002/30372 ,  A61F2002/3039 ,  A61F2002/30563 ,  A61F2002/30578 ,  A61F2002/30774 ,  A61F2002/30785 ,  A61F2002/30808 ,  A61F2002/30879 ,  A61F2002/30892 ,  A61F2002/30975 ,  A61F2002/443 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2210/0014 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2230/0019 ,  A61F2230/0021 ,  A61F2230/0069 ,  A61F2310/00023 ,  A61F2310/00976

摘要： An artificial disc implant (50) includes an upper shell (52), a lower shell (54), and a spacer (56) therebetween. The spacer preferably has properties similar to that of a natural spinal disc, while the upper and lower shells form a rigid interface between the implant and the adjacent vertebral bodies. The upper and lower shells can be configured to prevent expulsion of the spacer from the disc space. The implant upper and lower shells may further be configured into partially cylindrical shapes for ease of insertion through an insertion tube as presently known for interbody fusion devices. The devices may further be configured for insertion through a double-barreled insertion tube. Methods and instruments for inserting an artificial disc implant are also provided.

公开(公告)号：EP1330216A1

公开(公告)日：2003-07-30

申请号：EP01983145.2

申请日：2001-10-17

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F. ,  ESTES, Bradley, T.

IPC分类号： A61F2/46 ,  A61F2/44

CPC分类号： A61F2/4611 ,  A61B2090/062 ,  A61F2/442 ,  A61F2/446 ,  A61F2/4601 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30225 ,  A61F2002/30329 ,  A61F2002/30405 ,  A61F2002/30616 ,  A61F2002/30785 ,  A61F2002/30797 ,  A61F2002/3082 ,  A61F2002/3085 ,  A61F2002/4602 ,  A61F2002/4623 ,  A61F2002/4627 ,  A61F2002/4662 ,  A61F2220/0025 ,  A61F2230/0069 ,  A61F2250/0064

摘要： An osteogenic material packing device (100) is used to pack osteogenic material (3102) onto a spinal fusion device (2300). The packing device (100) has a cavity (302) defined therein, which is adapted to receive the spinal fusion device (2300). The packing device (100) further includes an access port (106), which intersects the cavity (302) to receive the osteogenic material (3102). A cannula (1400) is coupled to the packing device (100) and an inserter (2000) is coupled to the fusion device (2300) in order to insert the fusion device (2300) into the packing device (100). Osteogenic material (3102) is packed through the access port (106) around the fusion device (2300). The fusion device (2300) then is slid through the cannula (1400) and inserted in the intervertebral space between adjacent vertebrae.

公开(公告)号：EP1263353A2

公开(公告)日：2002-12-11

申请号：EP01918465.4

申请日：2001-03-09

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61F2/44

CPC分类号： A61L27/425 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/446 ,  A61F2/4611 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30777 ,  A61F2002/30785 ,  A61F2002/3082 ,  A61F2002/30841 ,  A61F2002/3085 ,  A61F2002/30909 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00293 ,  A61F2310/00329 ,  A61F2310/00365 ,  A61L27/04 ,  A61L27/042 ,  A61L27/06

摘要： Interbody fusion implants that include a load bearing body composed of a calcium phosphate material hardened around one or more structural reinforcing members are provided. The reinforcing members aid the load bearing body in resisting bending forces and, in certain forms, aid in preventing expulsion of the implant after implantation. Methods for promoting fusion bone growth in the space between adjacent vertebrae and methods for making the inventive implants are also provided.

公开(公告)号：EP1558182A2

公开(公告)日：2005-08-03

申请号：EP03752415.4

申请日：2003-09-16

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61F2/44

CPC分类号： A61F2/4455 ,  A61F2/28 ,  A61F2/442 ,  A61F2/446 ,  A61F2/447 ,  A61F2/4611 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30069 ,  A61F2002/30092 ,  A61F2002/30113 ,  A61F2002/30153 ,  A61F2002/30225 ,  A61F2002/30233 ,  A61F2002/30265 ,  A61F2002/30364 ,  A61F2002/3038 ,  A61F2002/30392 ,  A61F2002/30393 ,  A61F2002/30411 ,  A61F2002/30433 ,  A61F2002/30451 ,  A61F2002/30462 ,  A61F2002/30476 ,  A61F2002/3052 ,  A61F2002/30523 ,  A61F2002/30525 ,  A61F2002/3055 ,  A61F2002/30556 ,  A61F2002/30563 ,  A61F2002/30566 ,  A61F2002/30571 ,  A61F2002/30579 ,  A61F2002/30616 ,  A61F2002/30772 ,  A61F2002/30841 ,  A61F2002/3085 ,  A61F2002/30975 ,  A61F2002/4475 ,  A61F2210/0014 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0019 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2250/0009 ,  A61F2310/00293

摘要： An intervertebral disc space implant (8) includes spaced-apart bone engagement portions (30) that define an intermediate chamber that holds bone growth inducing material into contact with adjacent vertebral bodies. The implant (8) is expandable to establish and maintain desired intervertebral spacing during fusion. The implant (8) includes a first member (30) and a second member (30) arranged to move relative to each other by action of an expansion member (10), the first member being engageable with the vertebral body below the disc space.

公开(公告)号：EP1244388A2

公开(公告)日：2002-10-02

申请号：EP00992392.1

申请日：2000-12-06

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61B17/70

CPC分类号： A61F2/441 ,  A61F2/30965 ,  A61F2/442 ,  A61F2/4611 ,  A61F2002/2817 ,  A61F2002/30075 ,  A61F2002/30224 ,  A61F2002/3023 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2210/0061 ,  A61F2230/0069 ,  A61F2310/00365 ,  A61F2310/00377

摘要： Intervertebral disc treatment devices and methods are provided. An intervertebral disc treatment device (11) includes a fibrous body sized for introduction into a disc cavity (43) of a damaged disc wherein the body incorporates an effective amount of a tissue growth factor. Intervertebral disc treatment apparatuses are also described that include such a disc treatment device in combination with a delivery apparatus for retaining and selectively releasing the device into the disc cavity (43). Methods for treatment include providing a disc treatment device (11) as described above and inserting the device into an opening (44) in an annulus fibrous (42) and into the disc cavity (43). The methods further include stimulating tissue growth within the disc cavity (43) of the intervertebral disc (41).

公开(公告)号：EP1150725A1

公开(公告)日：2001-11-07

申请号：EP00905983.3

申请日：2000-02-04

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61L27/22 ,  A61L27/46 ,  A61K38/18 ,  A61L27/58

CPC分类号： A61L27/58 ,  A61K38/1875 ,  A61L27/227 ,  A61L27/46 ,  A61L2430/02 ,  C08L89/00

摘要： Described are osteogenic paste compositions with enhanced osteoinductive properties for use in bone repair. Compositions comprising a quickly resorbable paste carrier, a more slowly resorbed mineral matrix, and Bone Morphogenetic Protein (BMP) or other osteogenic factor are described which enable increased osteoinductive activity while retaining a reliable scaffold for the formation of new bone at the implant site. Methods for making and methods for therapeutic use of the compositions are also disclosed.

公开(公告)号：EP1673044A1

公开(公告)日：2006-06-28

申请号：EP04778972.2

申请日：2004-07-22

申请人： SDGI Holdings, Inc.

发明人： TRIEU, Hai, H. ,  MCKAY, William, F. ,  SERBOUSEK, Jon ,  SHERMAN, Michael, C.

IPC分类号： A61F2/44 ,  A61L27/36

CPC分类号： A61L27/3683 ,  A61F2/08 ,  A61F2/442 ,  A61F2002/30075 ,  A61F2002/30214 ,  A61F2002/30224 ,  A61F2002/30293 ,  A61F2002/30448 ,  A61F2002/30459 ,  A61F2002/30461 ,  A61F2002/30677 ,  A61F2002/30971 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/445 ,  A61F2210/0061 ,  A61F2220/005 ,  A61F2220/0066 ,  A61F2220/0075 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0091 ,  A61L27/3604 ,  A61L27/3612 ,  A61L27/3658 ,  A61L2430/38 ,  Y10S623/908 ,  Y10S623/919 ,  Y10S623/923

摘要： Allogenic or xenogenic materials are used to provide intervertebral disc nucleus implants and/or annular plugs. The allogenic or xenogenic materials comprise natural disc annulus material, which may have a portion of the anterior longitudinal ligament attached. The tissue may be used 'as is' without an additional core or covering, or it may be used in combination with other materials. The material may be rolled, folded, layered and/or sutured, stapled, or glued to provide a solid plug of natural biological material. The implant may be provided as a dehydrated, substantially rod-shaped segment having a diameter less than the diameter of the hydrated material, and may have one or more ends of the dehydrated rod terminate with a further reduced diameter portion, preferably a point.

公开(公告)号：EP1633291A1

公开(公告)日：2006-03-15

申请号：EP04754510.8

申请日：2004-06-04

申请人： SDGI Holdings, Inc.

发明人： RAY, Eddie, F. III ,  MCKAY, William, F. ,  REEVES, Cary, R. ,  SIMONTON, Thomas, A. ,  BIDSEIL, James, J.

IPC分类号： A61F2/44

CPC分类号： A61F2/4455 ,  A61F2/28 ,  A61F2/2846 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30057 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30235 ,  A61F2002/30245 ,  A61F2002/30261 ,  A61F2002/30293 ,  A61F2002/30448 ,  A61F2002/30451 ,  A61F2002/30461 ,  A61F2002/30464 ,  A61F2002/30472 ,  A61F2002/30588 ,  A61F2002/30604 ,  A61F2002/30622 ,  A61F2002/30772 ,  A61F2002/30971 ,  A61F2002/4495 ,  A61F2002/4649 ,  A61F2210/0004 ,  A61F2220/0041 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2230/0071 ,  A61F2230/0082 ,  A61F2230/0091 ,  A61F2310/00011 ,  A61F2310/00161 ,  A61F2310/00179 ,  A61F2310/00359

摘要： The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises at least one structural member (14) combined with at least one flexible planar (member16) to retain the at least one structural member to form the implant.

公开(公告)号：EP0836454B1

公开(公告)日：2005-04-20

申请号：EP96916786.5

申请日：1996-05-30

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61F2/44

CPC分类号： A61L27/42 ,  A61F2/44 ,  A61F2/442 ,  A61F2/4465 ,  A61F2002/30113 ,  A61F2002/30133 ,  A61F2002/30235 ,  A61F2002/30777 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30879 ,  A61F2002/30904 ,  A61F2002/4475 ,  A61F2230/0006 ,  A61F2230/0015 ,  A61F2230/0069 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00095 ,  A61F2310/00125 ,  A61F2310/00131 ,  A61F2310/00137 ,  A61F2310/00293 ,  A61F2310/00365 ,  A61L27/025 ,  A61L27/04 ,  A61L27/10 ,  A61L27/12 ,  A61L27/22 ,  A61L27/24 ,  A61L27/306 ,  A61L27/44 ,  A61L27/56 ,  A61L2430/38 ,  C08L89/00 ,  C08L89/06

摘要： One embodiment of a spinal implant 10 includes a body 11 sized and configured for engagement between adjacent vertebrae V. The body 11 includes two opposite faces 12, 14 and an outer surface 13 between the two faces 12, 14. The body 11 includes a porous biocompatible material for permitting tissue ingrowth therethrough. A sleeve 15 is disposed around the outer surface 13 of the body 11. The sleeve 15 is composed of a second material which is relatively stronger under compressive loads than the biocompatible material of the body 11. Also provided is a plurality of apertures 16 through the sleeve 15 in communication with the outer surface 13 of the body 11 for bone ingrowth. Means for attaching the sleeve to the endplates of adjoining vertebral bodies are also provided.

公开(公告)号：EP0988070B1

公开(公告)日：2004-09-15

申请号：EP98926323.1

申请日：1998-06-11

申请人： SDGI Holdings, Inc.

发明人： MCKAY, William, F.

IPC分类号： A61L27/00

CPC分类号： A61L27/3695 ,  A61L27/3608 ,  A61L27/365 ,  A61L2430/02 ,  Y10S530/84 ,  Y10S606/907 ,  Y10S606/908 ,  Y10S606/909 ,  Y10S606/912

摘要： A bone graft substitute including a composition of natural selectively deactivated bone material which has been processed to remove associated non-collagenous bone proteins, said bone material containing native collagen materials and naturally associated bone minerals and substantially free from native non-collagenous protein, and a therapeutically effective amount to stimulate bone growth of a bone growth factor in synergistic combination with said bone material. Spacers composed of the bone graft substitute composition and methods for using the spacers are also provided.