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公开(公告)号：EP4346616A1
公开(公告)日：2024-04-10
申请号：EP22730934.1
申请日：2022-06-03
申请人： SORBONNE UNIVERSITE , Centre National de la Recherche Scientifique , INSERM (Institut National de la Santé et de la Recherche Médicale)
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公开(公告)号：EP4011299A1
公开(公告)日：2022-06-15
申请号：EP20306553.7
申请日：2020-12-11
申请人： Sorbonne Université , Centre National de la Recherche Scientifique , INSERM (Institut National de la Santé et de la Recherche Médicale)
摘要： Device tracking system for monitoring a target body structure and localizing a device inside said target body structure, it comprising:
a control unit,
a device comprising one steering element (17) to be handled outside the target body structure, one steerable element (16) to be introduced inside the target body structure.
one probe (22) to be removably secured to the patient,
one tracker to be secured to the steerable element (16).
The control unit stores one ultrasound image of the target body structure. The probe (22) and the tracker communicate, and the control unit is able to localize, in real time, the steerable element (16). The control unit displays, the stored ultrasound image and displays, in real time, the localisation of the at steerable element (16) on said at least one ultrasound image.-
公开(公告)号：EP2652517B1
公开(公告)日：2014-10-08
申请号：EP11799794.0
申请日：2011-11-29
申请人： Centre National de la Recherche Scientifique (CNRS) , INSERM - Institut National de la Santé et de la Recherche Médicale , Université Paris Diderot - Paris 7
发明人： COUTURE, Olivier , TANTER, Mickael , FINK, Mathias
IPC分类号： G01S7/52
CPC分类号： G01S7/52 , G01S7/52041 , G01S7/52046
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公开(公告)号：EP2652517A1
公开(公告)日：2013-10-23
申请号：EP11799794.0
申请日：2011-11-29
申请人： Centre National de la Recherche Scientifique CNRS , INSERM - Institut National de la Santé et de la Recherche Médicale , Université Paris Diderot - Paris 7
发明人： COUTURE, Olivier , TANTER, Mickael , FINK, Mathias
IPC分类号： G01S7/52
CPC分类号： G01S7/52 , G01S7/52041 , G01S7/52046
摘要： Method of high-resolution ultrasound imaging, in which transducers (T
1 -T
n ) are made to emit ultrasound waves in a field of observations containing micro bubbles, by making the micro bubbles burst one by one in tandem with the emissions of ultrasound waves. At each shot j of an ultrasound wave, raw reverberated signals S
j (i,t) picked up by each transducer i are recorded, and then differential signals V
j (i,t) representative of variations between successive raw signals are determined, a parabolic function P
j (x) is fitted to the differential signals corresponding to each shot j, and then a crest A
j (x
0 ,y
0 ) of this function P
j , corresponding to the position of the micro bubble destroyed between shots j-1 and j, is determined.-
公开(公告)号：EP4258999A1
公开(公告)日：2023-10-18
申请号：EP21819529.5
申请日：2021-12-10
申请人： Robeaute , SORBONNE UNIVERSITE , Centre National de la Recherche Scientifique , Institut National de la Santé et de la Recherche Médicale (INSERM)
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6.发明公开
公开(公告)号：EP3899442A1
公开(公告)日：2021-10-27
申请号：EP19786639.5
申请日：2019-10-18
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7.发明公开EMULSION ACTIVABLE PAR ULTRASONS ET SON PROCEDE DE FABRICATION 审中-公开MITTELS ULTRASCHALL AKTIVIERBARE EMULSION UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2453875A1
公开(公告)日：2012-05-23
申请号：EP10742223.0
申请日：2010-07-07
CPC分类号： A61K9/0019 , A61B8/0833 , A61B8/481 , A61J3/00 , A61K9/0009 , A61K9/1075 , A61K41/0028
摘要： The invention relates to an emulsion that can be activated by ultrasounds, comprising, in an emulsion in an aqueous solution, microparticles (1) having a diameter (D) of less than 10 µm and containing an active agent and a gaseous precursor (3) in a liquid form, encapsulated by a first emulsifier (4). The microparticles contain nanoparticles (5) smaller than 1 µm, in an emulsion in the gaseous precursor, each nanoparticle comprising an inner liquid (6) that contains the active agent and is encapsulated by second emulsifier (7).
摘要翻译： 本发明涉及一种能够被超声波激活的乳液，其在水溶液中的乳液中包含直径小于10μm的微粒，并含有液体形式的活性剂和气体前体，其被第一 乳化剂。 微粒含有小于1μm的纳米颗粒，在气态前体中的乳液中，每个纳米颗粒包含含有活性剂并由第二乳化剂包封的内部液体。
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公开(公告)号：EP3377204B1
公开(公告)日：2019-12-25
申请号：EP16806262.8
申请日：2016-11-08
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公开(公告)号：EP3377204A1
公开(公告)日：2018-09-26
申请号：EP16806262.8
申请日：2016-11-08
申请人： Centre National de la Recherche Scientifique , Institut National de la Santé et de la Recherche Médicale , Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris
摘要： Method for producing an emulsion comprising droplets (1) in an external solution (2), the droplets containing a fluid (3). The fluid is circulated along a first main pipe (11), some of the fluid circulating in the first main pipe is bled off by a plurality of micro pipes (13) arranged in parallel between the first main pipe and a second main pipe (12) filled with external solution, the droplets are formed by hydrodynamic focusing as the fluid passes from each micro pipe into the second main pipe.
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10.发明公开PROCÉDÉ POUR ACTIVER UNE RÉACTION CHIMIQUE, SOLUTION ACTIVABLE PAR CE PROCÉDÉ ET DISPOSITIF POUR LA MISE EN OEUVRE DE CE PROCÉDÉ 审中-公开方法激活的化学反应，由实施过程中此过程活化溶液和设备
公开(公告)号：EP2943274A1
公开(公告)日：2015-11-18
申请号：EP14701806.3
申请日：2014-01-03
申请人： THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , Ecole Supérieure de Physique et Chimie Industrielles de la Ville de Paris , Institut National de la Santé et de la Recherche Médicale (INSERM)
CPC分类号： A61K9/0009 , A61K41/0028 , B01F13/0059 , B01F13/0071 , B01F15/0205 , B01J19/10 , B01J2219/00932 , B01J2219/0875 , B01J2219/0877
摘要： The invention relates to a method which comprises emitting ultrasound into a liquid mixture containing first and second reagents (A, B) in separate phases initially separated by a liquid precursor-gas barrier (3), the ultrasound having a high enough energy level to vaporise the precursor gas, such as to contact the reagents and thus to activate a chemical reaction therebetween.
摘要翻译： 本发明涉及方法，其包括超声发射到液体混合物包含在由液体前体的气体阻隔INITIALLY分离分开的相的第一和第二试剂，其具有足够高的能量水平的超声汽化的前体气体，检查，以接触 试剂，从而激活的化学反应在它们之间。
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