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1.发明公开
公开(公告)号：EP4053842A1
公开(公告)日：2022-09-07
申请号：EP22160175.0
申请日：2022-03-04
申请人： SYSMEX CORPORATION , OSAKA UNIVERSITY , National Institute Of Advanced Industrial Science and Technology
发明人： Okada, Masaya , Shimaoka, Yuki , Iwanaga, Shigeki , Bando, Kazuki , Fujita, Katsumasa , Nawa, Yasunori , Fujita, Satoshi
IPC分类号： G16C20/20
摘要： Disclosed is an analytical method for analyzing a test substance contained in a measurement sample, the method comprising: generating a data set based on a plurality of optical spectra acquired from a plurality of locations in the measurement sample; inputting the data set into a deep learning algorithm having a neural network structure; and outputting information on the test substance, on the basis of an analytical result from the deep learning algorithm.
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公开(公告)号：EP4053556A1
公开(公告)日：2022-09-07
申请号：EP22160173.5
申请日：2022-03-04
申请人： SYSMEX CORPORATION , OSAKA UNIVERSITY , National Institute Of Advanced Industrial Science and Technology
发明人： Shimaoka, Yuki , Okada, Masaya , Iwanaga, Shigeki , Bando, Kazuki , Fujita, Katsumasa , Nawa, Yasunori , Fujita, Satoshi
IPC分类号： G01N33/543
摘要： Disclosed is a preparation method for preparing a measurement sample comprising an aggregate of metal nanoparticles having an analyte bound thereto, the preparation method comprising: contacting the analyte with a linker to bind the analyte to the linker; and contacting the linker that has been bound to the analyte with the metal nanoparticles to bind the linker to the metal nanoparticles.
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公开(公告)号：EP3868838A3
公开(公告)日：2021-11-24
申请号：EP21154523.1
申请日：2021-02-01
发明人： Hara, Daiki , Motoki, Takafumi , Kazuta, Yuji , Norimine, Yoshihiko , Amino, Hiroyuki , Suganuma, Masatoshi , Fujiyama, Shingo , Yamashita, Kazuto , Okada, Masaya , Nishikawa, Yoichi , Iwanaga, Shigeki
摘要： Disclosed is: a fluorescent dye consisting of a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy. The fluorescent dye has formula (I):
wherein A represents an optionally substituted C4-C7 heterocyclic ring which contains an Si atom.-
公开(公告)号：EP3868838A2
公开(公告)日：2021-08-25
申请号：EP21154523.1
申请日：2021-02-01
发明人： Hara, Daiki , Motoki, Takafumi , Kazuta, Yuji , Norimine, Yoshihiko , Amino, Hiroyuki , Suganuma, Masatoshi , Fujiyama, Shingo , Yamashita, Kazuto , Okada, Masaya , Nishikawa, Yoichi , Iwanaga, Shigeki
摘要： Disclosed is: a fluorescent dye consisting of a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy. The fluorescent dye has formula (I):
wherein A represents an optionally substituted C4-C7 heterocyclic ring which contains an Si atom.-
5.发明公开
公开(公告)号：EP2182359A1
公开(公告)日：2010-05-05
申请号：EP09174417.7
申请日：2009-10-29
申请人： Sysmex Corporation
发明人： Iwanaga, Shigeki , Kirimura, Hiroya
IPC分类号： G01N33/543 , G01N27/00
CPC分类号： G01N33/54306 , G01N33/54366
摘要： A test chip for detecting an analyte modified with a modulator releasing electrons upon photoexcitation, comprising: a semiconductor electrode part including a metal layer formed on a semiconductor layer; a probe immobilized on the metal layer, the probe trapping the analyte; and a counter electrode part including a conductive layer. A detection apparatus and a method for detecting an analyte are also disclosed.
摘要翻译： 一种用于检测由光激发释放电子的调制剂修饰的分析物的测试芯片，包括：半导体电极部分，包括形成在半导体层上的金属层; 固定在金属层上的探针，探针捕获分析物; 以及包括导电层的对电极部。 还公开了检测装置和检测分析物的方法。
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公开(公告)号：EP3699574A1
公开(公告)日：2020-08-26
申请号：EP20157372.2
申请日：2020-02-14
申请人： SYSMEX CORPORATION
摘要： The present invention provides a method for determining a success or failure of a measurement of a target particle contained in a measurement sample. The method includes: detecting the target particle and other particle other than the target particle in the measurement sample; and determining the success or failure of the measurement of the target particle based on at least a detection result of the other particle.
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公开(公告)号：EP3217206A1
公开(公告)日：2017-09-13
申请号：EP17160079.4
申请日：2017-03-09
申请人： SYSMEX CORPORATION
发明人： Okada, Masaya , Iwanaga, Shigeki
IPC分类号： G02B21/00
CPC分类号： G02B27/0068 , G01N21/6458 , G02B21/0056 , G02B21/0064 , G02B21/0076
摘要： An optical device comprises a shared phase modulation mask configured to impart a first phase modulation to light of a first wavelength, and imparts a second phase modulation to light of a second wavelength, an irradiation optical system configured to cause the light of the first wavelength and the light of the second wavelength to enter the same incident region in the phase modulation mask, and a light collecting optical system configured to collect the light of the first phase-modulated first wavelength and the light of the second phase-modulated second wavelength to form an image corresponding to a point spread function.
摘要翻译： 一种光学器件，包括：共享相位调制掩模，被配置为对第一波长的光施加第一相位调制，并且对第二波长的光赋予第二相位调制;照射光学系统，被配置为引起第一波长的光;以及 第二波长的光进入相位调制掩模中的相同入射区域;以及光收集光学系统，配置为收集第一相位调制的第一波长的光和第二相位调制的第二波长的光以形成 对应于点扩散函数的图像。
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公开(公告)号：EP3699593A1
公开(公告)日：2020-08-26
申请号：EP20156118.0
申请日：2020-02-07
申请人： SYSMEX CORPORATION
IPC分类号： G01N33/543 , G01N33/58 , G01N33/68
摘要： PROBLEM TO BE SOLVED
The problem to be solved is to provide a measure to acquire information on the quantity or the structure of a polypeptide that is an analyte with high accuracy.
MEASURE TO SOLVE THE PROBLEM
The problem is solved by using, in an immune complex transfer method in which a capture substance that binds to the polypeptide that is an analyte, a first solid phase and a second solid phase, a capture substance binding to C-terminal region of the polypeptide as a capture substance binding to at least one of the fist solid phase and second solid phase.-
公开(公告)号：EP3640702A2
公开(公告)日：2020-04-22
申请号：EP19200083.4
申请日：2019-09-27
申请人： SYSMEX CORPORATION
发明人： Okada, Masaya , Iwanaga, Shigeki
摘要： A microscope apparatus is provided with: a sample setting unit in which a sample is set; an imaging unit configured to image the sample set in the sample setting unit; a housing unit on which the sample setting unit is arranged, and which is configured to internally accommodate the imaging unit; a first light source configured to irradiate light for fluorescence excitation on the sample in the sample setting unit; a first cover configured to be movable to a first position that covers the sample setting unit and a second position that opens the sample setting unit; and a second cover configured to be movable within the first cover so as to be in a closed state that covers the sample setting unit and an open state that opens the sample setting unit; and a second light source arranged in a space covered with the second cover and configured to irradiate light on the sample in the sample setting unit.
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公开(公告)号：EP2182359B1
公开(公告)日：2015-03-04
申请号：EP09174417.7
申请日：2009-10-29
申请人： Sysmex Corporation
发明人： Iwanaga, Shigeki , Kirimura, Hiroya
IPC分类号： G01N33/543 , G01N27/00
CPC分类号： G01N33/54306 , G01N33/54366
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