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公开(公告)号：EP1385870B1
公开(公告)日：2010-03-17
申请号：EP01954764.5
申请日：2001-07-19
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHAN, Viyyoor, Moopil , LOVEY, Raymond, G. , JAO, Edwin, E. , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , CHAN, Tin-Yau , LIU, Yi-Tsung , ZHU, Zhaoning , NJOROGE, F., George , ARASAPPAN, Ashok , PAREKH, Tejal, N. , GANGULY, Ashit, K. , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , VACCARO, Henry, A. , PINTO, Patrick A. , SANTHANAM, Bama , WU, Wanli , HENDRATA, Siska , HUANG, Yuhua , KEMP, Scott Jeffrey , LEVY, Odile Esther , LIM-WILBY, Marguerita , TAMURA, Susan Y.
IPC分类号： C07K1/00
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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公开(公告)号：EP1385870A2
公开(公告)日：2004-02-04
申请号：EP01954764.5
申请日：2001-07-19
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHAN, Viyyoor, Moopil , LOVEY, Raymond, G. , JAO, Edwin, E. , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , CHAN, Tin-Yau , LIU, Yi-Tsung , ZHU, Zhaoning , NJOROGE, F., George , ARASAPPAN, Ashok , PAREKH, Tejal, N. , GANGULY, Ashit, K. , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , VACCARO, Henry, A. , PINTO, Patrick A. , SANTHANAM, Bama , WU, Wanli , HENDRATA, Siska , HUANG, Yuhua , KEMP, Scott Jeffrey , LEVY, ODILE ESTHER , LIM-WILBY, Marguetita , TAMURA, Susan Y.
IPC分类号： C07K1/00
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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3.发明公开
公开(公告)号：EP1301528A2
公开(公告)日：2003-04-16
申请号：EP01959046.2
申请日：2001-07-19
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHAN, Viyyoor, Moopil , LOVEY, Raymond, G. , JAO, Edwin, E. , BENNETT, Frank , MCCORMICK, Jinping , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , LIU, Yi-Tsung , ARASAPPAN, Ashok , PAREKH, Tejal , PINTO, Patrick, A. , NJOROGE, F., George , GANGULY, Ashit, K. , BRUNCK, Terence, K. , KEMP, Scott, Jeffrey , LEVY, Odile, Esther , LIM-WILBY, Marguerita
摘要： The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.
摘要翻译： 本发明公开了具有HCV蛋白酶抑制活性的新型肽化合物以及制备该化合物的方法。 在另一个实施方案中，本发明公开了包含此类肽的药物组合物以及使用它们治疗与HCV蛋白酶相关的病症的方法。
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4.发明公开NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS 审中-公开NEW肽NS3蛋白酶抑制剂SERIN丙型肝炎病毒的
公开(公告)号：EP1303487A1
公开(公告)日：2003-04-23
申请号：EP01959041.3
申请日：2001-07-19
发明人： SAKESENA, Anil K. , GIRIJAVALLABHAN, Viyyoor, Moopil , BOGEN, Stephane, L. , LOVEY, Raymond, G. , JAO, Edwin, E. , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , LIU, Yi-Tsung , CHAN, Tin-Yau , ZHU, Zhaoning , ARASAPPAN, Ashok , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , PAREKH, Tejal, N. , PINTO, Patrick, A. , SANTHANAM, Bama , NJOROGE, F., George , GANGULY, Ashit K. , VACCARO, Henry A. , KEMP, Scott Jeffrey , LEVY, Odile Esther , LIM-WILBY, Marguerita , TAMURA, Susan Y.
IPC分类号： C07D209/02 , C07D211/04 , C07D233/56 , C07D317/10 , C07D319/04 , C07D339/02 , C07D339/08 , C07C229/00 , C07C233/05 , C07C271/08 , C07C271/32 , A61K31/16 , A61K31/27 , A61K31/195 , A61K31/357 , A61K31/385 , A61K31/403 , A61K31/445 , A61K31/4164
CPC分类号： C07K7/06 , A61K31/16 , A61K31/195 , A61K31/27 , A61K31/357 , A61K31/385 , A61K31/403 , A61K31/4164 , A61K31/445 , A61K38/05 , C07C205/51 , C07K5/101 , C07K7/02 , A61K2300/00
摘要： The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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