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1.发明授权HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF 有权HEXAHYDROPENTALENO衍生物，制备方法及其在其中的用途
公开(公告)号：EP2865666B1
公开(公告)日：2017-05-31
申请号：EP13809973.4
申请日：2013-06-25
发明人： GU, Zheng , QIU, Guanpeng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , LAN, Chengsheng , WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , YE, Kangzhi , SU, Guizhuan , TANG, PengCho
IPC分类号： C07D207/16 , C07D209/52 , C07D405/12 , A61K31/40 , A61K31/403 , A61K31/4025 , C07C213/02 , C07C217/52 , C07C215/44 , C07C255/47 , C07C253/30 , C07C219/24 , C07C211/41 , C07C209/62 , A61P3/10 , A61P9/10 , A61P25/00 , A61P13/12 , A61P5/50 , A61P3/04 , A61P3/06
CPC分类号： C07D207/16 , A61K31/40 , A61K31/4025 , A61K31/403 , A61K45/06 , C07C213/02 , C07C217/52 , C07C249/08 , C07C253/30 , C07C255/47 , C07C2601/02 , C07C2602/22 , C07C2603/94 , C07D209/52 , C07D405/12 , C07C251/34 , A61K2300/00
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公开(公告)号：EP2895490B1
公开(公告)日：2016-10-19
申请号：EP14847239.2
申请日：2014-09-26
发明人： WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , GU, Zheng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , TANG, Pengcho
IPC分类号： C07D493/08 , C07H15/04 , C07H1/00 , A61K31/357 , A61K31/422 , A61P3/10 , A61P3/04 , A61P9/12 , A61P9/10 , A61P3/06 , A61P13/12 , A61P25/00
CPC分类号： C07H15/00 , A61K31/7034 , A61K31/7048 , A61K45/06 , C07H7/04 , C07H9/04 , C07H15/04 , A61K2300/00
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公开(公告)号：EP2895490A1
公开(公告)日：2015-07-22
申请号：EP14847239.2
申请日：2014-09-26
发明人： WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , GU, Zheng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , TANG, Pengcho
IPC分类号： C07D493/08 , C07H15/04 , C07H1/00 , A61K31/357 , A61K31/422 , A61P3/10 , A61P3/04 , A61P9/12 , A61P9/10 , A61P3/06 , A61P13/12 , A61P25/00
CPC分类号： C07H15/00 , A61K31/7034 , A61K31/7048 , A61K45/06 , C07H7/04 , C07H9/04 , C07H15/04 , A61K2300/00
摘要： Disclosed are glucopyranosyl derivatives used as sodium dependent glucose cotransporters (SGLTs) inhibitors, intermediates or preparation processes thereof, and pharmaceutical uses thereof, especially glucopyranosyl derivatives represented by Formula (I), or pharmaceutically acceptable salts or all stereoisomers thereof, pharmaceutical compositions containing these derivatives and their uses for treatment of diabetes and diabetes-related diseases.
摘要翻译： 公开了用作钠依赖性葡萄糖协同转运蛋白（SGLT）抑制剂，其中间体或其制备方法的吡喃葡萄糖基衍生物及其药物用途，特别是由式（I）表示的吡喃葡萄糖基衍生物或其药学上可接受的盐或所有立体异构体，含有这些衍生物 以及它们用于治疗糖尿病和糖尿病相关疾病的用途。
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4.发明公开HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF 有权HEXAHYDROPENTALENODERIVATE，方法和使用中医药
公开(公告)号：EP2865666A1
公开(公告)日：2015-04-29
申请号：EP13809973.4
申请日：2013-06-25
发明人： GU, Zheng , QIU, Guanpeng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , LAN, Chengsheng , WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , YE, Kangzhi , SU, Guizhuan , TANG, PengCho
IPC分类号： C07D207/16 , C07D209/52 , C07D405/12 , A61K31/40 , A61K31/403 , A61K31/4025 , C07C213/02 , C07C217/52 , C07C215/44 , C07C255/47 , C07C253/30 , C07C219/24 , C07C211/41 , C07C209/62 , A61P3/10 , A61P9/10 , A61P25/00 , A61P13/12 , A61P5/50 , A61P3/04 , A61P3/06
CPC分类号： C07D207/16 , A61K31/40 , A61K31/4025 , A61K31/403 , A61K45/06 , C07C213/02 , C07C217/52 , C07C249/08 , C07C253/30 , C07C255/47 , C07C2601/02 , C07C2602/22 , C07C2603/94 , C07D209/52 , C07D405/12 , C07C251/34 , A61K2300/00
摘要： The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
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