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公开(公告)号：EP4036090A1
公开(公告)日：2022-08-03
申请号：EP20869854.8
申请日：2020-09-23
发明人： GU, Zheng , LI, Jianhao , DENG, Xinshan , LI, Zheng , CHEN, Daoqian , DENG, Jianchao , LV, Aizhen , LIU, Jianyu
IPC分类号： C07D403/10 , C07D253/075 , A61K31/53 , A61P5/16
摘要： Provided are a chemical compound as a thyroid hormone Beta receptor agonist and a use thereof, further comprising a pharmaceutical composition containing the chemical compound. The chemical compound or pharmaceutical composition can be used in the preparation of drugs for preventing, treating or mitigation of diseases mediated by agonistic thyroid hormone β receptor, particularly for the preparation of drugs for treating non-alcoholic fatty liver diseases.
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公开(公告)号：EP4215524A1
公开(公告)日：2023-07-26
申请号：EP21868667.3
申请日：2021-09-16
发明人： GU, Zheng , LI, Jianhao , DENG, Jianchao , LI, Yongxiang , QIN, Haoxiong , CHEN, Daoqian , ZHENG, Xiaomin , YU, Jianghong , ZHAO, Huantian
IPC分类号： C07D401/02 , C07D471/00 , A61K31/53 , A61K31/438 , A61P5/14 , A61P1/16 , A61P9/10 , A61P9/12 , A61P3/06 , A61P3/04 , A61P3/10 , A61P35/00
摘要： Provided are a compound serving as a thyroid hormone β receptor agonist and uses of the compound, also provided is a pharmaceutical composition comprising the compound. The compound or the pharmaceutical composition is applicable in preparing a medicament for preventing, treating, or alleviating thyroid hormone β receptor agonist-modulated diseases, and specifically applicable in preparing a medicament for treating nonalcoholic fatty liver disease.
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公开(公告)号：EP3997079A1
公开(公告)日：2022-05-18
申请号：EP20836913.2
申请日：2020-07-09
发明人： GU, Zheng , WU, Wuyong , KANG, Panpan , WANG, Weihua , LIU, Jianyu , DENG, Xinshan
IPC分类号： C07D309/10 , C07H7/04 , C07H9/04 , A61K31/35 , A61K31/351 , A61P3/10
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公开(公告)号：EP3371199A1
公开(公告)日：2018-09-12
申请号：EP16868062.7
申请日：2016-11-28
发明人： TANG, Pengcho , GU, Zheng , WU, Wuyong , ZHANG, Zongyuan , KANG, Panpan , QU, Tong
IPC分类号： C07H9/04 , C07H1/00 , C07D493/08 , C07D207/28 , A61K31/7048 , A61K31/357 , A61P3/10 , A61P3/06 , A61P3/04 , A61P9/10 , A61P9/12 , A61P13/12
CPC分类号： A61K31/357 , A61K31/401 , A61K31/7048 , A61K45/06 , A61K2300/00 , A61P5/48 , A61P9/10 , A61P13/12 , C07D207/28 , C07D493/08 , C07H1/00 , C07H9/04
摘要： This present invention relates to a complex of a glucopyranosyl derivative and L-pyroglutamic acid as a sodium dependent glucose cotransporter (SGLT) inhibitor, and preparation processes thereof, and a pharmaceutical composition containing the complex, and their uses in the manufacture of a medicament for treating diabetes and/or diabetes-related diseases.
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公开(公告)号：EP4178970A1
公开(公告)日：2023-05-17
申请号：EP21838814.8
申请日：2021-07-07
发明人： GU, Zheng , QU, Tong , WU, Wuyong , HUANG, Weiming , CHEN, Daoqian , ZHANG, Zongyuan , QIN, Haoxiong , LI, Zheng , YUAN, Weihui , NIU, Shijie , PENG, Fei , WU, Tianyun
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公开(公告)号：EP3995498A1
公开(公告)日：2022-05-11
申请号：EP19936158.5
申请日：2019-07-02
发明人： GU, Zheng , TANG, Wanjun , YANG, Xinye , WANG, Xuli , YUAN, Weihui , CUI, Yunzeng , YANG, Wen , LIU, Jianyu , ZHANG, Yingjun
IPC分类号： C07D495/04 , C07D519/00 , A61K31/519 , A61P35/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P3/00 , A61P1/16 , A61P5/50
摘要： Thienopyrimidine derivatives having stereo configurations and use thereof in medicine. Also comprised are pharmaceutical compositions of the compounds. The compounds or pharmaceutical compositions may be used to inhibit acetyl-CoA carboxylase (ACC). Also provided are a method for preparing the compounds and the pharmaceutical compositions, and use thereof in treatment or prevention of diseases associated with ACC regulation of mammals, in particular, humans.
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公开(公告)号：EP3571205A1
公开(公告)日：2019-11-27
申请号：EP18741820.7
申请日：2018-01-22
发明人： TANG, Wanjun , YANG, Xinye , GU, Zheng , LI, Chenlu , ZHANG, Zongyuan , WAN, Zhifu , WANG, Xiaojun , ZHANG, Yingjun
IPC分类号： C07D495/04 , C07D487/04 , A61K31/519 , A61K31/38 , A61P3/10 , A61P3/04 , A61P1/16 , A61P35/00
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8.发明授权HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF 有权HEXAHYDROPENTALENO衍生物，制备方法及其在其中的用途
公开(公告)号：EP2865666B1
公开(公告)日：2017-05-31
申请号：EP13809973.4
申请日：2013-06-25
发明人： GU, Zheng , QIU, Guanpeng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , LAN, Chengsheng , WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , YE, Kangzhi , SU, Guizhuan , TANG, PengCho
IPC分类号： C07D207/16 , C07D209/52 , C07D405/12 , A61K31/40 , A61K31/403 , A61K31/4025 , C07C213/02 , C07C217/52 , C07C215/44 , C07C255/47 , C07C253/30 , C07C219/24 , C07C211/41 , C07C209/62 , A61P3/10 , A61P9/10 , A61P25/00 , A61P13/12 , A61P5/50 , A61P3/04 , A61P3/06
CPC分类号： C07D207/16 , A61K31/40 , A61K31/4025 , A61K31/403 , A61K45/06 , C07C213/02 , C07C217/52 , C07C249/08 , C07C253/30 , C07C255/47 , C07C2601/02 , C07C2602/22 , C07C2603/94 , C07D209/52 , C07D405/12 , C07C251/34 , A61K2300/00
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公开(公告)号：EP3743412A1
公开(公告)日：2020-12-02
申请号：EP19744173.6
申请日：2019-01-22
发明人： GU, Zheng , WU, Wuyong , QU, Tong , KANG, Panpan , ZHANG, Zongyuan , HUANG, Weiming , LIU, Jianyu , ZHANG, Yingjun
IPC分类号： C07D309/10 , A61K31/351 , A61P3/10
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公开(公告)号：EP2895490B1
公开(公告)日：2016-10-19
申请号：EP14847239.2
申请日：2014-09-26
发明人： WEI, Yonggang , WEN, Jiaping , ZHU, Guozhi , LU, Yonghua , WANG, Heran , WANG, Yincai , YUAN, Mingyun , GU, Zheng , WU, Wuyong , KANG, Panpan , ZHANG, Zongyuan , CHEN, Gang , TANG, Pengcho
IPC分类号： C07D493/08 , C07H15/04 , C07H1/00 , A61K31/357 , A61K31/422 , A61P3/10 , A61P3/04 , A61P9/12 , A61P9/10 , A61P3/06 , A61P13/12 , A61P25/00
CPC分类号： C07H15/00 , A61K31/7034 , A61K31/7048 , A61K45/06 , C07H7/04 , C07H9/04 , C07H15/04 , A61K2300/00
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