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公开(公告)号：EP2604602A4
公开(公告)日：2013-12-18
申请号：EP11816483
申请日：2011-08-11
申请人： TAISHO PHARMA CO LTD
发明人： NAKAMURA TOSHIO , SAKAGAMI KAZUNARI , KONISHI KAZUHIDE , YAMAMOTO KANAKO , MASUDA SEIJI , MATSUDA YOHEI , OKADA KUMIKO , SHIBATA TSUYOSHI , OHTA HIROSHI , YASUHARA AKITO , KAWAMOTO HIROSHI , AMADA HIDEAKI , URABE HIROKI , NISHIKAWA RIE , KASHIWA SHUHEI
IPC分类号： C07D403/04 , A61K31/4155 , A61K31/4245 , A61K31/4439 , A61P25/04 , A61P25/08 , A61P25/20 , A61P25/22 , A61P25/28 , A61P25/36 , C07D403/14 , C07D413/04 , C07D413/14
CPC分类号： C07D413/14 , C07D231/38 , C07D403/04 , C07D403/14 , C07D413/04
摘要： A compound represented by formula [I] and a pharmaceutically accepted salt of said compound are a novel compound and a phamaceutically accepted salt thereof which exert antagonistic activity against group II metabotropic glutamate (mGlu) receptors, and are effective as a novel preventive or therapeutic agent for disorders such as mood disorders (depressive disorder, bipolar disorder, etc.), anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, posttraumatic stress disorder, a specific phobic disorder, acute stress disorder, etc.), schizophrenia, Alzheimer's disease, cognitive impairment, dementia, drug dependence, convulsions, shivering, pain, sleep disorders, and the like.
摘要翻译： 由式[I]表示的化合物和所述化合物的药学上可接受的盐是对II类代谢型谷氨酸（mGlu）受体发挥拮抗活性的新化合物及其药学上可接受的盐，并且作为新型预防剂或治疗剂 （抑郁症，双相性精神障碍等），焦虑症（广泛性焦虑症，恐慌症，强迫症，社交焦虑症，创伤后应激障碍，特定的恐怖症，急性应激障碍等） ），精神分裂症，阿尔茨海默病，认知障碍，痴呆，药物依赖，惊厥，寒战，疼痛，睡眠障碍等。
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公开(公告)号：EP1985620A4
公开(公告)日：2012-08-15
申请号：EP07706316
申请日：2007-02-07
发明人： SUGIMOTO TOMOHIRO , YAMAMOTO KANAKO , MANAKA AKIRA , OGITA HARUHISA , KUROSAKA JUN , KAWAMURA MADOKA , KASHIMURA MASATO , SASAMOTO NAOKI , MIURA TOMOAKI , KANEMOTO KENICHI , OZAWA TOMOHIRO , CHIKAUCHI KEN , SHITARA EIKI , KUBOTA DAI
IPC分类号： C07H17/00 , A61K31/7052 , A61P31/04
CPC分类号： C07H17/00 , A61K31/7052
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公开(公告)号：EP2678349A4
公开(公告)日：2014-07-30
申请号：EP12749570
申请日：2012-02-20
发明人： SUGIMOTO TOMOHIRO , SASAMOTO NAOKI , KUROSAKA JUN , HAYASHI MASATO , YAMAMOTO KANAKO , KASHIMURA MASATO , USHIKI YASUNOBU , OGITA HARUHISA , MIURA TOMOAKI , KANEMOTO KENICHI , KUMURA KOU , YOSHIDA SATOSHI , TAMURA KEIJI , SHITARA EIKI
IPC分类号： C07H17/08 , A61K31/7048 , A61P31/04
CPC分类号： C07H17/08
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公开(公告)号：EP2599775A4
公开(公告)日：2014-04-30
申请号：EP11812613
申请日：2011-07-29
申请人： TAISHO PHARMA CO LTD
发明人： NAKAMURA TOSHIO , SAKAGAMI KAZUNARI , KONISHI KAZUHIDE , YAMAMOTO KANAKO , MASUDA SEIJI , MATSUDA YOHEI , OKADA KUMIKO , SHIBATA TSUYOSHI , OHTA HIROSHI , YASUHARA AKITO , KAWAMOTO HIROSHI
IPC分类号： C07D231/12 , A61K31/415 , A61K31/4155 , A61K31/417 , A61K31/4174 , A61K31/42 , A61K31/4245 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/506 , A61P25/04 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/28 , A61P25/30 , A61P43/00 , C07D231/14
CPC分类号： C07D231/12 , C07D231/14 , C07D231/20 , C07D231/38 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/06 , C07D413/04
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公开(公告)号：EP2287173A4
公开(公告)日：2013-06-19
申请号：EP09746388
申请日：2009-05-15
发明人： SUGIMOTO TOMOHIRO , YAMAMOTO KANAKO , KUROSAKA JUN , SASAMOTO NAOKI , KASHIMURA MASATO , MIURA TOMOAKI , KANEMOTO KENICHI , YOSHIDA SATOSHI , KUMURA KOU , AJITO KEIICHI
IPC分类号： C07H17/00 , A61K31/7052 , A61P31/04
CPC分类号： C07H17/00
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6.发明公开
公开(公告)号：EP2177526A4
公开(公告)日：2012-08-22
申请号：EP08790393
申请日：2008-08-06
发明人： SUGIMOTO TOMOHIRO , YAMAMOTO KANAKO , KUROSAKA JUN , SASAMOTO NAOKI , KASHIMURA MASATO , MIURA TOMOAKI , KANEMOTO KENICHI , OZAWA TOMOHIRO , CHIKAUCHI KEN , SHITARA EIKI
IPC分类号： C07H17/00 , A61K31/7052 , A61P31/04
CPC分类号： C07H17/00
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