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公开(公告)号:EP3765028A1
公开(公告)日:2021-01-20
申请号:EP19767654.7
申请日:2019-03-14
发明人: JU, Jingyue , LI, Xiaoxu , KUMAR, Shiv , CHEN, Xin , RUSSO, James, J. , CHIEN, Minchen , JOCKUSCH, Steffen , TAO, Chuanjuan , WANG, Xuanting , KALACHIKOV, Sergey , MOROZOVA, Irina , SHI, Shundi
IPC分类号: A61K31/70 , A61K31/7042 , A61K31/7052 , C07H19/04 , C07H21/00 , C07H21/04
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公开(公告)号:EP3600339A1
公开(公告)日:2020-02-05
申请号:EP18774642.5
申请日:2018-03-28
发明人: JU, Jingyue , LI, Xiaoxu , CHEN, Xin , KUMAR, Shiv , RUSSO, James , CHIEN, Minchen
IPC分类号: A61K31/7052 , C07C323/60 , C07D207/40 , C07D207/46
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公开(公告)号:EP3997101A1
公开(公告)日:2022-05-18
申请号:EP20836455.4
申请日:2020-07-09
发明人: JU, Jingyue , KUMAR, Shiv , RUSSO, James , LI, Xiaoxu , CHEN, Xin , CHIEN, Minchen , JOCKUSCH, Steffen , WANG, Xuanting , MOROZOVA, Irina , TAO, Chuanjuan , KALACHIKOV, Sergey , SHI, Shundi
IPC分类号: C07H21/00 , C12Q1/6823 , C12Q1/6869
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公开(公告)号:EP3274471B1
公开(公告)日:2020-05-06
申请号:EP16769553.5
申请日:2016-03-22
发明人: JU, Jingyue , CHO, Youngjin , KUMAR, Shiv , KALACHIKOV, Sergey , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J.
IPC分类号: C12Q1/6869 , C12Q1/6827 , G01N33/487 , G01N15/00
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公开(公告)号:EP3947659A1
公开(公告)日:2022-02-09
申请号:EP20784059.6
申请日:2020-04-02
发明人: JU, Jingyue , KUMAR, Shiv , RUSSO, James , LI, Xiaoxu , JOCKUSCH, Steffen , CHIEN, Minchen , TAO, Chuanjuan
IPC分类号: C12N9/12 , C12Q1/6818 , C12Q1/6869
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6.POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY 审中-公开
标题翻译: 用于单分子电子SNP测定的聚合物标记的核苷酸公开(公告)号:EP3274471A1
公开(公告)日:2018-01-31
申请号:EP16769553.5
申请日:2016-03-22
发明人: JU, Jingyue , CHO, Youngjin , KUMAR, Shiv , KALACHIKOV, Sergey , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J.
IPC分类号: C12Q1/68 , G01N15/00 , G01N33/487
摘要: This invention provides methods of using labeled nucleotide polyphosphate analogues to detect the identity or presence of a nucleotide at certain positions in nucleic acid sequences with single molecule sensitivity using nanopore detection, nucleotides and primer-conjugated nanopore proteins for use in such methods, and processes for producing such nucleotides and primer-conjugated nanopore proteins.
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7.METHOD OF PREPARATION OF NANOPORE AND USES THEREOF 审中-公开
标题翻译: VERFAHREN ZUR HERSTELLUNG VON NANOPOREN UND VERWENDUNGEN DAVON公开(公告)号:EP2836604A2
公开(公告)日:2015-02-18
申请号:EP13775787.8
申请日:2013-04-08
申请人: The Trustees of Columbia University in the City of New York , Government of The United States of America, As Represented by The Secretary of Commerce
发明人: JU, Jingyue , KUMAR, Shiv , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James J. , KASIANOVICZ, John J. , ROBERTSON, Joseph W.F.
IPC分类号: C12Q1/42
CPC分类号: C12Q1/6883 , B82Y5/00 , C07H19/06 , C07H19/16 , C12Q1/42 , C12Q1/48 , C12Q1/6869 , C12Q2600/158 , G01N33/48721 , G01N2333/9125 , C12Q2521/525 , C12Q2521/543 , C12Q2535/107 , C12Q2565/631
摘要: This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to composition, method, and system for sequencing a nucleic acid using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.
摘要翻译: 本公开提供了使用核苷酸类似物对核酸进行测序的系统和方法,以及通过纳米孔从掺入的核苷酸类似物转移标签。 在一些方面,本公开涉及使用标签分子对核酸测序的组合物,方法和系统,以及通过从分子掺入释放的标记的纳米孔的易位检测。
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8.DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION 有权
标题翻译: DNA合成测序使用修饰的核苷酸和纳米多孔PROOF公开(公告)号:EP2652153A2
公开(公告)日:2013-10-23
申请号:EP11848220.7
申请日:2011-12-16
发明人: JU, Jingyue , KUMAR, Shiv , LI, Zengmin , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J. , KALACHIKOV, Sergey , SHEPARD, Ken , ROSENSTEIN, Jacob, Karl
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C07H19/10 , C07H21/00 , G01N33/48721 , C12Q2525/113 , C12Q2525/117 , C12Q2565/518 , C12Q2565/631
摘要: This disclosure is related to a method of sequencing a single- stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.
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公开(公告)号:EP3105354B1
公开(公告)日:2020-05-06
申请号:EP15749646.4
申请日:2015-02-12
发明人: TAO, Chuanjuan , KUMAR, Shiv , CHIEN, Minchen , JU, Jingyue
IPC分类号: C12Q1/6858
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公开(公告)号:EP3463381A1
公开(公告)日:2019-04-10
申请号:EP17803398.1
申请日:2017-05-23
发明人: JU, Jingyue , CHEN, Xin , LI, Xiaoxu , LI, Zengmin , HSIEH, Min-Kang , CHIEN, Minchen , SHI, Shundi , REN, Jianyi , GUO, Cheng , KUMAR, Shiv , RUSSO, James, J. , TAO, Chuanjuan , JOCKUSCH, Steffen , KALACHIKOV, Sergey
IPC分类号: A61K31/70 , A61K31/7042 , A61K31/7052 , C07H19/04 , C07H21/00 , C07H21/04
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