摘要:
Provided is a method for producing polybutylene terephthalate resin particles, which includes (a) a step of heating a polybutyl terephthalate resin in an organic solvent to obtain a solution of a polybutylene terephthalate resin (dissolution step), and (b) a step of flash-cooling the solution to precipitate polybutylene terephthalate resin particles (precipitation step). The present invention provides a method for producing PBT resin particles by a simple operation that can be performed industrially. The present invention also provides extremely fine PBT resin particles of uniform particle size.
摘要:
Prevention or therapy of inflammatory diseases caused by invasion of leukocytes such as monocytes, lymphocytes and eosinophils, by providing a substance which inhibits cell adhesion via an adhesion molecule, especially adhesion molecule VLA-4, is disclosed. A group of carboxylic acid derivatives represented by, for example, and adhesion molecule inhibitors comprising the same as an effective ingredient were provided.
摘要:
2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives such as 16-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 17-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 15-phenyl-2,5,6,7,16,17,18,19,20-nonanor-4,8-inter-m-phenylene PGI2, 16-methyl-17-phenyl-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2, 16,16-dimethyl-17-phenyl-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2, 16-methyl-16-phenoxy-2,5,6,7,17,18,19,20-octanor-4,8-inter-m-phenylene PGI2, 16-methyl-16-phenoxy-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2 and its methyl ester and 3-decarboxy-3-hydroxymethyl-16-methyl-16-phenoxy-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2, useful as medicines, are disclosed. These derivatives are useful as, for example, antiulceric agents, hypotensives, and antithrombotic agents.
摘要:
The present invention provides a process to produce fine particles of polyamide-imide resin that can be carried out industrially by simple operations with a high reproducibility. It also provides very fine PAI resin particles with a uniform particle size. The invention provides a production process for fine PAI resin particles comprising a dissolution steps and a precipitation step as described below: [Dissolution step] A step selected from the undermentioned steps (a1) and (b1) (a1) PAI resin is dissolved in an organic solvent to prepare a PAI resin solution A1 having a PAI resin content of less than 5 mass%, (b1) PAI resin is dissolved in an organic solvent to prepare a PAI resin solution B1 having a PAI resin content of less than 10 mass%. [Precipitation step] (a2) The PAI resin solution A1 is added to a solvent that is virtually free from surface active agents and able to precipitate fine PAI resin particles, in order to cause the precipitation of fine PAI resin particles, (b2) The PAI resin solution B1 is subjected to flash crystallization to cause the precipitation of fine PAI resin particles.
摘要:
The present invention provides a process to produce fine particles of polyamide-imide resin that can be carried out industrially by simple operations with a high reproducibility. It also provides very fine PAI resin particles with a uniform particle size. The invention provides a production process for fine PAI resin particles comprising a dissolution steps and a precipitation step as described below: [Dissolution step] A step selected from the undermentioned steps (a1) and (b1) (a1) PAI resin is dissolved in an organic solvent to prepare a PAI resin solution A1 having a PAI resin content of less than 5 mass%, (b1) PAI resin is dissolved in an organic solvent to prepare a PAI resin solution B1 having a PAI resin content of less than 10 mass%.
[Precipitation step] (a2) The PAI resin solution A1 is added to a solvent that is virtually free from surface active agents and able to precipitate fine PAI resin particles, in order to cause the precipitation of fine PAI resin particles, (b2) The PAI resin solution B1 is subjected to flash crystallization to cause the precipitation of fine PAI resin particles.
摘要:
Novel triazolo derivatives represented by the following formula and pharmaceutically acceptable salts thereof, as well as chemokine inhibitors containing the same as an effective component. These are useful as therapeutic agents for allergic diseases such as bronchial asthma and atopic dermatitis; therapeutic agents for inflammatory diseases such as chronic rheumatoid arthritis; therapeutic agents for autoimmune diseases such as ulcerative colitis and nephritis; and as anti-AIDS drugs.
摘要:
Disclosed are novel spiro derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases. The spiro derivative according to the present invention has the chemical structure, for example, represented by the following Formula (31):
摘要:
Disclosed are novel urea derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases. The urea derivative according to the present invention has the chemical structure, for example, represented by the following Formula (35):
摘要:
This invention provides a process for producing fine PPS resin particles and a dispersion thereof by industrially applicable simple operation. This invention further provides very fine PPS resin particles, and furthermore provides fine PPS resin particles uniform in particle size. This invention is a process for producing fine polyphenylene sulfide resin particles comprising the following steps (a) and (b) : (a) A step of heating a polyphenylene sulfide resin in an organic solvent, for obtaining a solution with the polyphenylene sulfide resin dissolved therein (dissolution step) (b) A step of flush-cooling the aforementioned solution, for precipitating the fine particles of the polyphenylene sulfide resin (precipitation step).